Detailed information NTG0650169

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: OHS71_RS18440
• Genome accession: NZ_CP107958
• Coordinates: 4102579..4105104 (-)
• Length: 841 a.a.
• NCBI ID: WP_328480468.1
• Uniprot ID: -
• Organism: Streptomyces sp. NBC_00377
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 4097579..4110104

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OHS71_RS18425 (OHS71_18410)	-	4099068..4099655 (+)	588	WP_328480465.1	TetR/AcrR family transcriptional regulator	-
OHS71_RS18430 (OHS71_18415)	-	4099697..4100281 (-)	585	WP_328480466.1	M23 family metallopeptidase	-
OHS71_RS18435 (OHS71_18420)	-	4100800..4101447 (+)	648	WP_328480467.1	HAD family acid phosphatase	-
OHS71_RS18440 (OHS71_18425)	clpC	4102579..4105104 (-)	2526	WP_328480468.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
OHS71_RS18445 (OHS71_18430)	-	4105535..4106194 (+)	660	WP_328480469.1	SCO3374 family protein	-
OHS71_RS18450 (OHS71_18435)	-	4106173..4106508 (-)	336	WP_328480470.1	Lsr2 family protein	-
OHS71_RS18455 (OHS71_18440)	-	4106734..4107282 (-)	549	WP_328480471.1	amino-acid N-acetyltransferase	-
OHS71_RS18460 (OHS71_18445)	-	4107292..4107732 (-)	441	WP_328480472.1	BlaI/MecI/CopY family transcriptional regulator	-
OHS71_RS18465 (OHS71_18450)	-	4107879..4108058 (-)	180	WP_328480473.1	hypothetical protein	-
OHS71_RS18470 (OHS71_18455)	-	4108110..4108799 (-)	690	WP_328484556.1	hypothetical protein	-
OHS71_RS18475 (OHS71_18460)	-	4109048..4109845 (-)	798	WP_328480474.1	type III pantothenate kinase	-

Sequence

Protein

• Length: 841 a.a.
• Molecular weight: 92985.21 Da
• Isoelectric Point: 5.9363

>NTDB_id=650169 OHS71_RS18440 WP_328480468.1 4102579..4105104(-) (clpC) [Streptomyces sp. NBC_00377]
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKALESLGISLEAVRQQVEEIIGQGQQAPSGHIPF
TPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGADLNRVRQQVIQLLSGYQGKETATAGGPAEGT
PSTSLVLDQFGRNLTQAARESKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVKGEVPETLKD
KHLYTLDLGALVAGSRYRGDFEERLKKVLKEIRTRGDIILFIDELHTLVGAGAAEGAIDAASILKPMLARGELQTIGATT
LDEYRKHLEKDAALERRFQPIQVAEPSLPHTIEILKGLRDRYEAHHRVSITDEALVQAATLADRYISDRFLPDKAIDLID
EAGSRMRIRRMTAPPDLREFDEKIAGVRRDKESAIDSQDFEKAASLRDKEKQLLAAKAKREKEWKAGDMDVVAEVDGELI
AEVLATATGIPVFKLTEEESSRLLRMEDELHKRVIGQVDAVKALSKAIRRTRAGLKDPKRPGGSFIFAGPSGVGKTELSK
ALAEFLFGDEDALISLDMSEFSEKHTVSRLFGSPPGYVGYEEGGQLTEKVRRKPFSVVLFDEVEKAHPDIFNSLLQILED
GRLTDSQGRVVDFKNTVIIMTTNLGTRDISKGFNLGFAASGDKKSNYERMKNKVSDELKQHFRPEFLNRVDDVVVFPQLT
QEDILQIVDLMIGKVDERLKDRDMGIELSQAAKELLSKKGYDPVLGARPLRRTIQREIEDTLSEKILFGELRPGHIVVVD
TEGEGETKTFTFRGEEKSALPDVPPIEQAAGGAGPNLSKDA

Nucleotide

• Length: 2526 bp

>NTDB_id=650169 OHS71_RS18440 WP_328480468.1 4102579..4105104(-) (clpC) [Streptomyces sp. NBC_00377]
ATGTTCGAGAGGTTCACCGACCGCGCGCGGCGGGTTGTCGTCCTGGCTCAGGAAGAAGCCCGGATGCTCAACCACAACTA
CATCGGCACCGAGCACATCCTCCTGGGCCTGATCCACGAGGGTGAGGGTGTCGCCGCCAAGGCCCTTGAGAGCCTCGGGA
TTTCGCTCGAGGCGGTCCGCCAGCAGGTGGAGGAGATCATCGGTCAGGGCCAGCAGGCCCCGTCCGGCCACATCCCCTTC
ACCCCCCGTGCCAAGAAGGTCCTGGAGCTGTCGCTCCGCGAGGCCCTTCAGCTGGGTCACAACTACATCGGCACGGAGCA
CATCCTGCTCGGCCTGATCCGCGAGGGCGAGGGCGTCGCCGCCCAGGTCCTCGTCAAGCTGGGCGCAGATCTGAACCGGG
TGCGGCAGCAGGTCATCCAGCTGCTCTCCGGCTACCAGGGCAAGGAGACCGCCACCGCCGGCGGCCCTGCCGAGGGCACG
CCCTCGACGTCTCTGGTCCTCGACCAGTTCGGCCGGAACCTCACCCAGGCCGCTCGTGAGTCCAAGCTCGACCCGGTCAT
CGGGCGCGAGAAGGAGATCGAGCGGGTCATGCAGGTGCTGTCCCGCCGTACCAAGAACAACCCGGTCCTGATCGGTGAGC
CCGGCGTCGGCAAGACCGCCGTCGTCGAAGGCCTCGCCCAGGCCATCGTCAAGGGCGAGGTGCCCGAGACCCTCAAGGAC
AAGCACCTCTACACCCTGGACCTCGGCGCCCTGGTCGCCGGCTCCCGCTACCGCGGTGACTTCGAGGAGCGCCTGAAGAA
GGTCCTCAAGGAGATCCGCACCCGCGGCGACATCATCCTGTTCATCGACGAGCTGCACACGCTGGTCGGTGCGGGTGCCG
CCGAGGGCGCCATCGACGCCGCTTCGATCCTGAAGCCGATGCTGGCCCGTGGTGAGCTCCAGACCATCGGTGCGACCACG
CTGGACGAGTACCGCAAGCACCTGGAGAAGGACGCGGCCCTCGAGCGCCGCTTCCAGCCCATCCAGGTCGCGGAGCCGTC
CCTGCCGCACACGATCGAGATCCTCAAGGGTCTGCGTGACCGGTACGAGGCGCACCACCGTGTCTCGATCACCGACGAGG
CGCTGGTCCAGGCCGCCACCCTGGCCGACCGGTACATCTCGGACCGCTTCCTGCCGGACAAGGCGATCGACCTGATCGAC
GAGGCCGGTTCCCGGATGCGCATCCGCCGGATGACCGCGCCGCCGGACCTGCGCGAGTTCGACGAGAAGATCGCCGGCGT
CCGCCGCGACAAGGAGTCCGCGATCGACTCGCAGGACTTCGAGAAGGCCGCCTCCCTCCGCGACAAGGAGAAGCAGCTCC
TGGCCGCCAAGGCCAAGCGGGAGAAGGAGTGGAAGGCCGGCGACATGGACGTCGTCGCCGAGGTCGACGGCGAGCTCATC
GCCGAGGTCCTCGCCACGGCCACCGGCATCCCGGTCTTCAAGCTGACCGAGGAGGAGTCCTCGCGTCTGCTGCGCATGGA
GGACGAGCTCCACAAGCGGGTCATCGGCCAGGTCGACGCCGTCAAGGCGCTGTCGAAGGCGATCCGGCGTACGCGTGCGG
GCCTCAAGGACCCGAAGCGTCCGGGTGGTTCGTTCATCTTCGCCGGCCCCTCCGGTGTCGGTAAGACCGAGCTGTCCAAG
GCGCTCGCCGAGTTCCTCTTCGGTGACGAGGACGCGCTGATCTCCCTCGACATGTCGGAGTTCAGCGAGAAGCACACGGT
GTCGCGTCTCTTCGGTTCGCCCCCCGGATACGTGGGCTACGAAGAGGGCGGCCAGCTGACCGAGAAGGTCCGTCGCAAGC
CGTTCTCCGTCGTCCTCTTCGACGAGGTCGAGAAGGCCCACCCGGACATTTTCAACTCGCTGCTCCAGATCCTGGAGGAC
GGTCGTCTGACCGACTCCCAGGGCCGGGTCGTGGACTTCAAGAACACGGTCATCATCATGACGACCAACCTCGGCACCCG
GGACATCTCCAAGGGCTTCAACCTGGGCTTCGCGGCCTCGGGCGACAAGAAGTCCAACTACGAGCGCATGAAGAACAAGG
TCTCGGACGAGCTCAAGCAGCACTTCCGCCCCGAGTTCCTCAACCGTGTCGACGACGTGGTCGTCTTCCCGCAGCTGACG
CAGGAGGACATCCTGCAGATCGTCGACCTGATGATCGGCAAGGTCGACGAGCGCCTCAAGGACCGGGACATGGGCATCGA
GCTCTCCCAGGCCGCGAAGGAGCTGCTGTCGAAGAAGGGCTACGACCCGGTGCTGGGTGCGCGTCCGCTGCGTCGCACCA
TCCAGCGCGAGATCGAGGACACGCTCTCGGAGAAGATCCTCTTCGGTGAGCTGCGCCCCGGTCACATCGTGGTCGTGGAC
ACGGAGGGCGAGGGTGAGACCAAGACCTTCACCTTCCGCGGCGAGGAGAAGTCGGCTCTGCCGGACGTCCCGCCGATCGA
GCAGGCGGCCGGCGGCGCCGGACCGAACCTGAGCAAGGACGCCTGA

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (541-712)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (93-142)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (16-68)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (719-799)

• AAA lid domain (AAA_lid_9) (349-449)

• ATPase family associated with various cellular activities (AAA) (AAA) (209-329)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	61.481	96.314	0.592
clpC	Streptococcus mutans UA159	44.217	98.692	0.436
clpC	Streptococcus thermophilus LMD-9	43.011	99.524	0.428
clpC	Streptococcus thermophilus LMG 18311	42.84	99.643	0.427
clpC	Streptococcus pneumoniae Rx1	44.085	95.482	0.421
clpC	Streptococcus pneumoniae D39	44.085	95.482	0.421
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	43.704	96.314	0.421
clpC	Streptococcus pneumoniae TIGR4	44.11	94.887	0.419
clpE	Streptococcus mutans UA159	54.313	74.435	0.404
clpE	Streptococcus pneumoniae TIGR4	52.97	74.078	0.392
clpC	Lactococcus lactis subsp. cremoris KW2	53.226	73.722	0.392
clpE	Streptococcus pneumoniae R6	52.809	74.078	0.391
clpE	Streptococcus pneumoniae D39	52.809	74.078	0.391
clpE	Streptococcus pneumoniae Rx1	52.809	74.078	0.391