Detailed information NTG0650167

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: OHS71_RS18385
• Genome accession: NZ_CP107958
• Coordinates: 4089992..4091116 (+)
• Length: 374 a.a.
• NCBI ID: WP_328480458.1
• Uniprot ID: -
• Organism: Streptomyces sp. NBC_00377
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 4084992..4096116

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OHS71_RS18370 (OHS71_18355)	-	4085642..4086421 (+)	780	WP_328484555.1	hypothetical protein	-
OHS71_RS18375 (OHS71_18360)	-	4086474..4088225 (-)	1752	WP_328480456.1	hypothetical protein	-
OHS71_RS18380 (OHS71_18365)	radA/sms	4088502..4089911 (+)	1410	WP_328480457.1	DNA repair protein RadA	Machinery gene
OHS71_RS18385 (OHS71_18370)	disA	4089992..4091116 (+)	1125	WP_328480458.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
OHS71_RS18390 (OHS71_18375)	-	4091287..4092153 (-)	867	WP_328480459.1	hypothetical protein	-
OHS71_RS18395 (OHS71_18380)	-	4092415..4093347 (+)	933	WP_328480460.1	A/G-specific adenine glycosylase	-
OHS71_RS18400 (OHS71_18385)	-	4093648..4094190 (+)	543	WP_190149519.1	SigE family RNA polymerase sigma factor	-
OHS71_RS18405 (OHS71_18390)	-	4094175..4094834 (+)	660	WP_328480461.1	hypothetical protein	-
OHS71_RS18410 (OHS71_18395)	cseB	4095107..4095808 (+)	702	WP_328480462.1	two-component system response regulator CseB	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40015.82 Da
• Isoelectric Point: 5.0025

>NTDB_id=650167 OHS71_RS18385 WP_328480458.1 4089992..4091116(+) (disA) [Streptomyces sp. NBC_00377]
MAANDRAAAPGKSGGSSGAEGLMRAALSAVAPGTALRDGLERILRGNTGGLIVLGSDKTVEAMCTGGFVLNVEFAATRLR
ELCKLDGGIVVSSDLSKILRAGVQLVPDPMIPTEETGTRHRTADRVSKQVGFPVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVDEALYELDALSHAELLELSTVARALGYTGSPEALDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=650167 OHS71_RS18385 WP_328480458.1 4089992..4091116(+) (disA) [Streptomyces sp. NBC_00377]
GTGGCAGCCAACGACCGGGCGGCAGCTCCCGGAAAGTCCGGTGGGAGTTCCGGTGCCGAGGGCCTGATGCGCGCCGCGCT
GAGCGCGGTGGCTCCCGGCACGGCCCTGCGTGACGGACTGGAACGGATCCTCCGCGGCAACACCGGCGGGCTCATCGTGC
TGGGCTCCGACAAGACGGTCGAGGCGATGTGTACGGGCGGGTTCGTCCTGAACGTGGAGTTCGCGGCCACGCGCCTGCGC
GAGCTGTGCAAGCTCGACGGCGGCATCGTGGTCTCCTCGGACCTGTCGAAGATCCTGCGGGCCGGCGTCCAGCTGGTACC
GGACCCCATGATCCCCACGGAGGAGACGGGCACCCGGCACCGCACCGCGGACCGGGTCAGCAAGCAGGTCGGCTTCCCCG
TGGTCTCGGTCTCCCAGTCCATGCGGCTGATCGCCCTCTACGTCGACGGGCAGCGCCGCGTCCTGGAGGATTCCGCGGCG
ATCCTGTCCCGTGCGAACCAGGCACTGGCGACCCTCGAGCGGTACAAGCTCCGCCTGGACGAGGTCGCGGGAACGTTGTC
AGCGCTGGAGATCGAGGACCTGGTCACGGTCCGGGACGTCTCCGCGGTGGCCCAGCGCCTGGAGATGGTGCGCCGCATCG
CCACCGAAATCGCCGAATACGTGGTCGAACTGGGCACGGACGGCCGTCTGCTCGCCCTTCAGCTCGACGAGTTGATCGCG
GGCGTGGAGCCGGAGCGCGAGCTGGTGGTCCGGGACTACGTGCCGGAACCCACGGCGAAGCGGTCCCGCACGGTCGACGA
GGCGCTGTACGAGCTGGACGCGCTCAGCCACGCCGAACTGCTCGAACTCTCCACGGTGGCCCGCGCGTTGGGTTACACCG
GCTCCCCCGAGGCACTGGACTCGGCGGTCTCGCCCCGCGGCTTCCGGCTGCTGGCGAAGGTGCCGCGCCTGCCGGGTGCC
ATCATCGACCGGCTCGTCGAGCACTTCGGCGGACTCCAGAAGCTCCTCGCCGCGAGTGTCGACGACCTCCAGACGGTGGA
CGGCGTGGGCGAGGCAAGGGCCCGCAGCGTCCGCGAGGGCCTGTCAAGGCTGGCCGAGTCGTCGATCCTGGAGCGGTACG
TCTAG

Domains

Predicted by InterProScan.

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	46.286	93.583	0.433