Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHO27_RS07680 Genome accession   NZ_CP107917
Coordinates   1700077..1700757 (-) Length   226 a.a.
NCBI ID   WP_328421576.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00443     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1695077..1705757
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHO27_RS07660 (OHO27_07670) - 1695639..1696787 (-) 1149 WP_328421569.1 ROK family glucokinase -
  OHO27_RS07665 (OHO27_07675) - 1696927..1697664 (-) 738 WP_328430376.1 GntR family transcriptional regulator -
  OHO27_RS07670 (OHO27_07680) - 1697794..1698816 (+) 1023 WP_328421572.1 Gfo/Idh/MocA family oxidoreductase -
  OHO27_RS07675 (OHO27_07685) - 1698855..1700033 (-) 1179 WP_328421574.1 cytochrome P450 -
  OHO27_RS07680 (OHO27_07690) vraR 1700077..1700757 (-) 681 WP_328421576.1 response regulator transcription factor Regulator
  OHO27_RS07685 (OHO27_07695) - 1700851..1702095 (-) 1245 WP_328421578.1 histidine kinase -
  OHO27_RS07690 (OHO27_07700) - 1702274..1702474 (+) 201 Protein_1533 hypothetical protein -
  OHO27_RS07695 (OHO27_07705) - 1702536..1702922 (-) 387 WP_328421580.1 ribonuclease domain-containing protein -
  OHO27_RS07700 (OHO27_07710) - 1703077..1703703 (-) 627 WP_328421582.1 dihydrofolate reductase family protein -
  OHO27_RS07705 (OHO27_07715) - 1703887..1704654 (+) 768 WP_328421585.1 3-oxoacyl-ACP reductase family protein -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 24215.60 Da        Isoelectric Point: 4.7693

>NTDB_id=649134 OHO27_RS07680 WP_328421576.1 1700077..1700757(-) (vraR) [Streptomyces sp. NBC_00443]
MTAIRLLLVDDDPLVRAGLSFMLGGADDIEIVGEAADGSEVEALVDRSRPDVVLMDIRMPSVDGLTATERLRSRKDAPQV
VLLTTFHADDQVLRALRAGAAGFVLKDTPPAEIVDAVRRVAAGDPVLSPTVTRQLMAHAAGTAADTRRSHARERLTALND
REREVAVAVGRGLSNADIAAELFMSVATVKTHVSRVLAKLDLNNRVQIALLAYDAGLLEELEDDGH

Nucleotide


Download         Length: 681 bp        

>NTDB_id=649134 OHO27_RS07680 WP_328421576.1 1700077..1700757(-) (vraR) [Streptomyces sp. NBC_00443]
ATGACTGCGATCAGACTCCTCCTCGTCGACGACGACCCGTTGGTCAGGGCCGGGCTGTCCTTCATGCTGGGCGGCGCCGA
CGACATCGAGATCGTCGGTGAGGCGGCCGACGGCTCCGAGGTCGAGGCACTGGTCGACCGCTCTCGGCCGGACGTGGTCC
TGATGGACATCCGGATGCCGTCGGTCGACGGACTCACCGCCACGGAGCGGCTGCGCAGCAGGAAGGACGCGCCGCAGGTC
GTGCTGCTGACCACGTTCCATGCCGACGATCAGGTGCTGCGCGCCCTGCGCGCGGGCGCCGCCGGTTTCGTGCTCAAGGA
CACGCCGCCCGCCGAGATCGTCGACGCGGTGCGCCGGGTCGCGGCCGGCGATCCGGTCCTGTCGCCCACCGTCACACGCC
AGTTGATGGCCCACGCGGCCGGCACCGCCGCCGACACCCGCCGCTCACACGCGCGGGAGCGGCTCACCGCCCTCAACGAC
CGCGAGCGCGAGGTCGCCGTCGCGGTGGGCCGGGGGCTGTCCAACGCTGACATCGCCGCGGAGCTCTTCATGAGCGTCGC
CACCGTCAAGACCCATGTCTCCCGCGTCCTGGCCAAGCTGGACCTCAACAACCGTGTGCAGATCGCCCTGTTGGCTTACG
ACGCGGGACTTCTGGAGGAACTGGAGGACGACGGGCACTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(158-212)

Response regulator receiver domain (Response_reg)

(7-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.073

96.46

0.367