Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHA71_RS11725 Genome accession   NZ_CP107916
Coordinates   2554673..2555353 (-) Length   226 a.a.
NCBI ID   WP_328437699.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00444     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2549673..2560353
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHA71_RS11705 (OHA71_11705) - 2549814..2550998 (-) 1185 WP_210571822.1 ROK family glucokinase -
  OHA71_RS11710 (OHA71_11710) - 2551140..2551877 (-) 738 WP_210572238.1 GntR family transcriptional regulator -
  OHA71_RS11715 (OHA71_11715) - 2552008..2553030 (+) 1023 WP_328353261.1 Gfo/Idh/MocA family oxidoreductase -
  OHA71_RS11720 (OHA71_11720) - 2553397..2554575 (-) 1179 WP_328437698.1 cytochrome P450 -
  OHA71_RS11725 (OHA71_11725) vraR 2554673..2555353 (-) 681 WP_328437699.1 response regulator transcription factor Regulator
  OHA71_RS11730 (OHA71_11730) - 2555401..2556651 (-) 1251 WP_328437700.1 histidine kinase -
  OHA71_RS11735 (OHA71_11735) - 2556832..2557032 (+) 201 WP_328353273.1 hypothetical protein -
  OHA71_RS11740 (OHA71_11740) - 2557036..2557173 (-) 138 Protein_2343 ribonuclease domain-containing protein -
  OHA71_RS11745 (OHA71_11745) - 2557681..2559087 (+) 1407 WP_328437701.1 transcriptional regulator -
  OHA71_RS11750 (OHA71_11750) - 2559069..2559653 (+) 585 WP_328437702.1 helix-turn-helix domain containing protein -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 24238.72 Da        Isoelectric Point: 4.8999

>NTDB_id=649031 OHA71_RS11725 WP_328437699.1 2554673..2555353(-) (vraR) [Streptomyces sp. NBC_00444]
MTAIRVLLVDDDPLVRAGLSFMMGGAEDIEIVGEAADGREVEALVDRTSPDVVLMDIRMPSMDGLTATERLRGRKDAPQV
VVLTTFHADEQVLRALRAGAAGFVLKDTPPAEIVDAVRRVAAGDPVLSPSVTRRLMEHAAGGAADTRRARARARIEALND
REREVAVAVGRGLSNAEIAATLFMSVATVKTHVSRILAKLDLNNRVQIALLAYDAGLLEESEEDGH

Nucleotide


Download         Length: 681 bp        

>NTDB_id=649031 OHA71_RS11725 WP_328437699.1 2554673..2555353(-) (vraR) [Streptomyces sp. NBC_00444]
ATGACTGCGATCAGAGTGCTCCTCGTCGACGACGACCCCCTCGTACGGGCCGGGCTGTCCTTCATGATGGGCGGGGCCGA
GGACATCGAGATCGTCGGGGAGGCGGCCGACGGCCGTGAGGTCGAGGCACTCGTCGACCGCACCAGCCCGGACGTCGTCC
TGATGGACATCCGGATGCCGTCGATGGACGGGCTGACGGCCACCGAGCGGCTGCGCGGCCGTAAGGACGCCCCGCAGGTC
GTGGTCCTGACCACCTTCCACGCCGACGAGCAGGTGCTGCGGGCGCTGCGCGCCGGTGCCGCCGGATTCGTCCTGAAGGA
CACCCCGCCCGCCGAGATCGTCGACGCGGTGCGCCGGGTCGCGGCCGGCGACCCCGTCCTGTCGCCCTCCGTCACCCGCC
GGCTGATGGAGCACGCGGCCGGTGGCGCGGCCGACACCCGGCGGGCACGCGCGCGTGCCCGCATCGAGGCCCTCAACGAC
CGTGAACGCGAGGTCGCCGTCGCGGTCGGCCGGGGGCTGTCCAACGCCGAGATCGCCGCCACCCTCTTCATGAGCGTGGC
CACCGTCAAGACCCATGTCTCCCGCATCCTGGCCAAGCTCGACCTCAACAACCGTGTGCAGATCGCCCTGTTGGCATACG
ACGCGGGACTTCTGGAGGAATCCGAGGAGGACGGGCACTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(6-118)

Bacterial regulatory proteins, luxR family (GerE)

(157-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.545

97.345

0.385