Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG800_RS10835 Genome accession   NZ_CP107914
Coordinates   2358649..2359329 (-) Length   226 a.a.
NCBI ID   WP_328353267.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00445     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2353649..2364329
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG800_RS10815 (OG800_10810) - 2353813..2354997 (-) 1185 WP_210571822.1 ROK family glucokinase -
  OG800_RS10820 (OG800_10815) - 2355139..2355876 (-) 738 WP_210572238.1 GntR family transcriptional regulator -
  OG800_RS10825 (OG800_10820) - 2356007..2357029 (+) 1023 WP_328353261.1 Gfo/Idh/MocA family oxidoreductase -
  OG800_RS10830 (OG800_10825) - 2357387..2358565 (-) 1179 WP_328353264.1 cytochrome P450 -
  OG800_RS10835 (OG800_10830) vraR 2358649..2359329 (-) 681 WP_328353267.1 response regulator transcription factor Regulator
  OG800_RS10840 (OG800_10835) - 2359377..2360627 (-) 1251 WP_328353270.1 histidine kinase -
  OG800_RS10845 (OG800_10840) - 2360808..2361008 (+) 201 WP_328353273.1 hypothetical protein -
  OG800_RS10850 (OG800_10845) - 2361012..2361161 (-) 150 WP_328353276.1 ribonuclease domain-containing protein -
  OG800_RS10855 (OG800_10850) - 2361560..2363065 (+) 1506 WP_328353279.1 helix-turn-helix domain-containing protein -
  OG800_RS10860 (OG800_10855) - 2363047..2363631 (+) 585 WP_328353282.1 helix-turn-helix domain-containing protein -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 24222.72 Da        Isoelectric Point: 4.8999

>NTDB_id=648919 OG800_RS10835 WP_328353267.1 2358649..2359329(-) (vraR) [Streptomyces sp. NBC_00445]
MTAIRVLLVDDDPLVRAGLSFMMGGAEDIEIVGEAADGREVEALVDRTSPDVVLMDIRMPSMDGLTATERLRGRKDAPQV
VVLTTFHADEQVLRALRAGAAGFVLKDTPPAEIVDAVRRVAAGDPVLSPSVTRRLMEHAAGAAADTRRARARARIEALND
REREVAVAVGRGLSNAEIAAALFMSVATVKTHVSRILAKLDLNNRVQIALLAYDAGLLEESEEDGH

Nucleotide


Download         Length: 681 bp        

>NTDB_id=648919 OG800_RS10835 WP_328353267.1 2358649..2359329(-) (vraR) [Streptomyces sp. NBC_00445]
ATGACTGCGATCAGAGTGCTCCTCGTCGACGACGACCCCCTCGTACGGGCCGGGCTGTCCTTCATGATGGGCGGGGCCGA
GGACATCGAGATCGTCGGGGAGGCGGCCGACGGCCGTGAGGTCGAGGCACTCGTCGACCGCACCAGCCCGGACGTCGTCC
TGATGGACATCCGGATGCCGTCGATGGACGGGCTGACGGCCACCGAGCGGCTGCGCGGCCGTAAGGACGCCCCGCAGGTC
GTGGTCCTGACCACCTTCCACGCCGACGAGCAGGTGCTGCGGGCGCTGCGCGCCGGTGCCGCCGGATTCGTCCTGAAGGA
CACCCCGCCCGCCGAGATCGTCGACGCGGTGCGCCGGGTCGCGGCCGGCGACCCCGTCCTGTCTCCCTCCGTCACCCGCC
GGCTGATGGAGCACGCGGCCGGTGCCGCGGCCGACACCCGGCGGGCACGCGCGCGTGCCCGCATCGAGGCCCTCAACGAC
CGTGAACGCGAGGTCGCCGTCGCGGTCGGCCGGGGCCTGTCCAACGCCGAGATCGCCGCCGCCCTCTTCATGAGCGTGGC
CACCGTCAAGACCCATGTCTCCCGCATCCTGGCCAAGCTCGACCTCAACAACCGTGTGCAGATCGCCCTGTTGGCATACG
ACGCGGGACTTCTGGAGGAATCCGAGGAGGACGGGCACTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(6-118)

Bacterial regulatory proteins, luxR family (GerE)

(157-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40

97.345

0.389