Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   L3C11_RS12475 Genome accession   NZ_CP091288
Coordinates   2457469..2458113 (+) Length   214 a.a.
NCBI ID   WP_003152052.1    Uniprot ID   A3KLB8
Organism   Bacillus velezensis strain JJ47     
Function   promoting transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 2452469..2463113
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L3C11_RS12450 (L3C11_12450) - 2452917..2453258 (-) 342 WP_032876795.1 hypothetical protein -
  L3C11_RS12455 (L3C11_12455) degQ 2453724..2453864 (+) 141 WP_003152043.1 degradation enzyme regulation protein DegQ Regulator
  L3C11_RS12460 (L3C11_12460) - 2454072..2454932 (+) 861 WP_142925231.1 polyprenyl synthetase family protein -
  L3C11_RS12465 (L3C11_12465) comX 2454901..2455074 (+) 174 WP_012118314.1 competence pheromone ComX -
  L3C11_RS12470 (L3C11_12470) comP 2455088..2457388 (+) 2301 WP_032876801.1 histidine kinase Regulator
  L3C11_RS12475 (L3C11_12475) comA 2457469..2458113 (+) 645 WP_003152052.1 response regulator transcription factor Regulator
  L3C11_RS12480 (L3C11_12480) - 2458135..2458518 (+) 384 WP_007613430.1 hotdog fold thioesterase -
  L3C11_RS12485 (L3C11_12485) mnhG 2458558..2458932 (-) 375 WP_007613429.1 monovalent cation/H(+) antiporter subunit G -
  L3C11_RS12490 (L3C11_12490) - 2458916..2459200 (-) 285 WP_017419420.1 Na(+)/H(+) antiporter subunit F1 -
  L3C11_RS12495 (L3C11_12495) - 2459200..2459676 (-) 477 WP_007613428.1 Na+/H+ antiporter subunit E -
  L3C11_RS12500 (L3C11_12500) - 2459682..2461163 (-) 1482 WP_032876804.1 Na+/H+ antiporter subunit D -
  L3C11_RS12505 (L3C11_12505) - 2461156..2461497 (-) 342 WP_032876807.1 Na(+)/H(+) antiporter subunit C -
  L3C11_RS12510 (L3C11_12510) - 2461497..2461928 (-) 432 WP_007613424.1 Na(+)/H(+) antiporter subunit B -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24271.68 Da        Isoelectric Point: 4.9953

>NTDB_id=648910 L3C11_RS12475 WP_003152052.1 2457469..2458113(+) (comA) [Bacillus velezensis strain JJ47]
MKKILVIDDHPAVMEGTKTILETDTNLSVDCLSPDASEQFVLRHDFSAYDLILMDLNLGDDISGIELSKKILKENPLCKI
IVYTGYEVEDYFEESIRAGLHGAISKTESKEKIMQYIYHVLNGQILVDFSYFKQLMTQQKTKTSSSPQSEQDRLTPRERH
ILQEVEKGLTNQEIADALHLSKRSIEYSLTSIFNKLNVGSRTEAVLIAKSDNVL

Nucleotide


Download         Length: 645 bp        

>NTDB_id=648910 L3C11_RS12475 WP_003152052.1 2457469..2458113(+) (comA) [Bacillus velezensis strain JJ47]
ATGAAAAAGATACTAGTGATTGATGATCATCCGGCTGTCATGGAGGGCACCAAGACGATTCTGGAAACGGACACGAATCT
TTCTGTCGATTGCCTCAGTCCTGATGCCAGTGAACAATTTGTTCTCCGGCATGATTTTTCAGCTTACGATCTCATATTAA
TGGATTTAAATCTGGGTGATGACATCAGCGGCATAGAGCTTTCCAAGAAAATCTTAAAAGAGAATCCTCTCTGTAAAATC
ATTGTCTACACAGGCTATGAGGTTGAAGATTATTTTGAAGAATCCATCCGCGCGGGCCTGCATGGCGCCATCAGCAAAAC
CGAATCTAAAGAGAAAATCATGCAATACATATATCACGTGCTCAACGGACAGATTTTAGTTGATTTCTCCTATTTCAAAC
AGCTGATGACCCAGCAAAAAACAAAAACGTCTTCTTCCCCTCAAAGTGAGCAGGATCGGTTAACCCCGAGAGAGCGCCAT
ATTCTCCAAGAGGTCGAAAAAGGTTTGACCAATCAGGAAATCGCAGATGCGCTTCACTTAAGCAAGCGGTCGATTGAATA
CAGTCTGACATCCATTTTTAATAAGCTGAATGTCGGCTCCCGCACTGAAGCGGTGCTGATCGCCAAGTCAGATAACGTAC
TATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-117)

Bacterial regulatory proteins, luxR family (GerE)

(153-208)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A3KLB8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Bacillus subtilis subsp. subtilis str. 168

86.449

100

0.864