Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHN74_RS34825 Genome accession   NZ_CP107903
Coordinates   7904404..7905084 (+) Length   226 a.a.
NCBI ID   WP_327698540.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00459     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 7899404..7910084
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHN74_RS34800 (OHN74_34790) - 7900417..7900587 (+) 171 WP_327698535.1 hydrophobic protein -
  OHN74_RS34805 (OHN74_34795) - 7900928..7901323 (-) 396 WP_327698536.1 ribonuclease domain-containing protein -
  OHN74_RS34810 (OHN74_34800) - 7901510..7901710 (-) 201 WP_327698537.1 hypothetical protein -
  OHN74_RS34815 (OHN74_34805) - 7901888..7903237 (+) 1350 WP_327698538.1 histidine kinase -
  OHN74_RS34820 (OHN74_34810) - 7903274..7904308 (-) 1035 WP_327698539.1 aldo/keto reductase -
  OHN74_RS34825 (OHN74_34815) vraR 7904404..7905084 (+) 681 WP_327698540.1 response regulator transcription factor Regulator
  OHN74_RS34830 (OHN74_34820) - 7905270..7906283 (-) 1014 WP_327698541.1 Gfo/Idh/MocA family oxidoreductase -
  OHN74_RS34835 (OHN74_34825) - 7906402..7907151 (+) 750 WP_327700380.1 GntR family transcriptional regulator -
  OHN74_RS34840 (OHN74_34830) - 7907291..7908481 (+) 1191 WP_327698542.1 ROK family glucokinase -
  OHN74_RS34845 (OHN74_34835) - 7908478..7909080 (+) 603 WP_327698543.1 sugar kinase -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 23744.25 Da        Isoelectric Point: 4.9455

>NTDB_id=648543 OHN74_RS34825 WP_327698540.1 7904404..7905084(+) (vraR) [Streptomyces sp. NBC_00459]
MTVIRLLLVDDDPLVRAGLSFMMGGADDIEIVGEAADGSEVEALVGRTGPDVVLMDIRMPTVDGLAATERLRALKDAPQV
VVLTTFHADDQVLRALRAGAAGFVLKDTPPAEILAAVRRVAAGDPVLSPAVTRQLMAHAAGGTADTRRAGARERMGALND
REREVAVAVGQGRANAEIAAALFMSVATVKTHVSRILAKLDLNNRVQIALLAYDAGLLEENGQDGH

Nucleotide


Download         Length: 681 bp        

>NTDB_id=648543 OHN74_RS34825 WP_327698540.1 7904404..7905084(+) (vraR) [Streptomyces sp. NBC_00459]
ATGACCGTGATCAGACTGCTCCTCGTCGATGACGACCCCCTGGTACGGGCGGGTCTGTCCTTCATGATGGGCGGCGCCGA
CGACATCGAGATCGTCGGCGAGGCCGCCGACGGCAGCGAGGTCGAGGCGCTCGTCGGCCGTACCGGCCCGGACGTCGTGC
TCATGGACATCCGGATGCCGACGGTGGACGGCCTCGCCGCCACCGAACGTCTGCGGGCCCTCAAGGACGCCCCGCAGGTC
GTGGTCCTCACCACCTTCCACGCCGACGACCAGGTACTGCGCGCCCTGCGCGCGGGTGCCGCCGGCTTCGTCCTCAAGGA
CACCCCGCCCGCCGAGATCCTCGCCGCGGTACGCCGTGTCGCGGCCGGCGACCCCGTCCTGTCGCCCGCCGTGACCCGCC
AGTTGATGGCCCACGCGGCGGGCGGCACCGCCGACACCCGGCGGGCAGGTGCCCGGGAGCGGATGGGTGCGCTGAACGAC
CGGGAACGCGAGGTCGCGGTCGCCGTCGGCCAGGGCAGGGCGAACGCCGAGATCGCCGCCGCCCTGTTCATGAGCGTCGC
CACCGTCAAGACGCACGTCTCCCGCATCCTCGCCAAGCTGGACCTCAACAACCGAGTACAGATCGCCCTGTTGGCGTACG
ACGCAGGACTCCTGGAAGAGAACGGGCAGGACGGGCACTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-118)

Bacterial regulatory proteins, luxR family (GerE)

(158-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

37.615

96.46

0.363