Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG870_RS36660 Genome accession   NZ_CP107902
Coordinates   7910413..7911093 (+) Length   226 a.a.
NCBI ID   WP_327691919.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00461     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 7905413..7916093
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG870_RS36630 (OG870_36610) - 7905721..7906467 (-) 747 WP_266524950.1 3-oxoacyl-ACP reductase family protein -
  OG870_RS36635 (OG870_36615) - 7906581..7907393 (+) 813 WP_266524952.1 AIM24 family protein -
  OG870_RS36640 (OG870_36620) - 7907483..7908109 (+) 627 WP_327691918.1 dihydrofolate reductase family protein -
  OG870_RS36645 (OG870_36625) - 7908242..7908637 (+) 396 WP_266524956.1 ribonuclease domain-containing protein -
  OG870_RS36650 (OG870_36630) - 7908730..7908930 (-) 201 WP_266926970.1 hypothetical protein -
  OG870_RS36655 (OG870_36635) - 7909100..7910365 (+) 1266 WP_266524961.1 sensor histidine kinase -
  OG870_RS36660 (OG870_36640) vraR 7910413..7911093 (+) 681 WP_327691919.1 response regulator transcription factor Regulator
  OG870_RS36665 (OG870_36645) - 7911164..7911378 (+) 215 Protein_7243 cytochrome P450 -
  OG870_RS36670 (OG870_36650) - 7911470..7912492 (-) 1023 WP_266524965.1 Gfo/Idh/MocA family oxidoreductase -
  OG870_RS36675 (OG870_36655) - 7912622..7913359 (+) 738 WP_266525817.1 GntR family transcriptional regulator -
  OG870_RS36680 (OG870_36660) - 7913535..7914683 (+) 1149 WP_266525819.1 ROK family glucokinase -
  OG870_RS36685 (OG870_36665) - 7914680..7915264 (+) 585 WP_266524967.1 sugar kinase -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 24047.55 Da        Isoelectric Point: 4.9825

>NTDB_id=648448 OG870_RS36660 WP_327691919.1 7910413..7911093(+) (vraR) [Streptomyces sp. NBC_00461]
MTAIRLLLVDDDPLVRAGLSLMMGGADDIEIVGEAADGSEVEALVDRTRPDVVLMDIRMPSVDGLTATERLRGRKDAPQV
VVLTTFHADEQVLRALRAGAAGFVLKDTPPAEIVDAVRRVAVGDPVLSPTVTRQLMEHAVGGGADTRRTHARVRIAALND
REREAAVAVGRGLSNAEIAAALFMSVATVKTHVSRILAKLDLNNRVQIALLAYDAGLLEEPDGDGH

Nucleotide


Download         Length: 681 bp        

>NTDB_id=648448 OG870_RS36660 WP_327691919.1 7910413..7911093(+) (vraR) [Streptomyces sp. NBC_00461]
ATGACTGCGATCAGACTGCTCCTCGTCGACGACGACCCCCTGGTACGGGCCGGCCTGTCCCTGATGATGGGCGGCGCCGA
CGACATCGAGATCGTCGGCGAGGCCGCCGACGGCTCCGAGGTCGAGGCGCTCGTCGATCGCACCCGCCCGGACGTGGTCC
TCATGGACATCCGGATGCCGTCGGTGGACGGCCTCACGGCCACCGAACGGCTGCGCGGCCGCAAGGACGCCCCGCAGGTC
GTCGTCCTCACCACCTTCCACGCCGACGAACAGGTGCTGCGCGCCCTGCGCGCGGGTGCCGCCGGATTCGTCCTCAAGGA
CACCCCGCCCGCCGAGATCGTCGACGCGGTGCGTCGGGTCGCGGTCGGTGACCCCGTGCTGTCGCCCACCGTCACACGGC
AGTTGATGGAGCACGCCGTCGGCGGCGGCGCCGACACCCGGCGCACGCACGCGCGCGTGCGCATCGCCGCCCTCAACGAC
CGCGAACGCGAGGCCGCCGTGGCGGTCGGCCGCGGTCTGTCCAACGCCGAGATCGCCGCCGCCCTGTTCATGAGCGTCGC
CACCGTCAAGACCCATGTGTCCCGGATCCTGGCCAAGCTCGACCTCAACAACCGTGTGCAGATCGCCTTGTTGGCGTACG
ACGCGGGACTGCTGGAGGAACCGGACGGCGACGGGCACTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-118)

Bacterial regulatory proteins, luxR family (GerE)

(157-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.356

96.903

0.372