Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG250_RS34675 Genome accession   NZ_CP107877
Coordinates   8017927..8018568 (+) Length   213 a.a.
NCBI ID   WP_327730378.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00487     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 8012927..8023568
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG250_RS34655 (OG250_34705) - 8013784..8014455 (-) 672 WP_327730375.1 transglycosylase SLT domain-containing protein -
  OG250_RS34660 (OG250_34710) - 8014753..8015853 (-) 1101 WP_327730376.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
  OG250_RS34665 (OG250_34715) - 8015850..8016545 (-) 696 WP_327730377.1 SDR family NAD(P)-dependent oxidoreductase -
  OG250_RS34670 (OG250_34720) - 8016789..8017934 (+) 1146 WP_326583788.1 GAF domain-containing sensor histidine kinase -
  OG250_RS34675 (OG250_34725) vraR 8017927..8018568 (+) 642 WP_327730378.1 response regulator transcription factor Regulator
  OG250_RS34680 (OG250_34730) chpE 8018726..8018974 (+) 249 WP_033529228.1 chaplin ChpE -
  OG250_RS34685 (OG250_34735) - 8019200..8019985 (-) 786 WP_327730379.1 hypothetical protein -
  OG250_RS34690 (OG250_34740) - 8020136..8020927 (+) 792 WP_326583791.1 ABC transporter ATP-binding protein -
  OG250_RS34695 (OG250_34745) - 8021073..8021504 (+) 432 WP_327730380.1 NfeD family protein -
  OG250_RS34700 (OG250_34750) - 8021664..8022611 (+) 948 WP_326583793.1 SPFH domain-containing protein -
  OG250_RS34705 (OG250_34755) - 8022739..8023245 (-) 507 WP_216590898.1 HNH endonuclease -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 22901.12 Da        Isoelectric Point: 4.9871

>NTDB_id=647673 OG250_RS34675 WP_327730378.1 8017927..8018568(+) (vraR) [Streptomyces sp. NBC_00487]
MADAIKVLLVDDHQVVRRGLRTFLEVQDDIEVVGEAADGAEGVARAEELRPDVVLMDVKMPGMDGVDALRKLRELDNPAR
VLIVTSFTEQRTVVPALRAGAAGYVYKDVDPDALAGAIRSVHAGHVLLQPEVADALLSQEQANSGQGRGGSLTEREREVL
GLIADGRSNREIARALVLSEKTVKTHVSNILMKLDLADRTQAALWAVRNGVAG

Nucleotide


Download         Length: 642 bp        

>NTDB_id=647673 OG250_RS34675 WP_327730378.1 8017927..8018568(+) (vraR) [Streptomyces sp. NBC_00487]
GTGGCTGACGCAATCAAGGTGCTCCTGGTCGACGACCACCAGGTGGTCCGGCGCGGCCTGCGCACCTTCCTGGAGGTGCA
GGACGACATCGAGGTCGTGGGGGAGGCCGCCGACGGCGCCGAGGGAGTCGCCCGCGCCGAGGAGCTCCGGCCCGACGTCG
TCCTCATGGACGTCAAGATGCCGGGCATGGACGGCGTCGACGCGCTGCGCAAGCTCCGCGAACTCGACAACCCCGCGCGT
GTGCTCATCGTCACCAGCTTCACCGAGCAGCGCACGGTCGTCCCGGCCCTGCGCGCCGGCGCCGCCGGATACGTCTACAA
GGACGTGGACCCCGACGCCCTGGCCGGCGCCATCCGCTCGGTGCACGCCGGGCACGTCCTCCTCCAGCCGGAGGTCGCCG
ACGCGCTCCTGTCCCAGGAGCAGGCCAACTCCGGCCAGGGGAGAGGAGGTTCACTCACCGAGCGGGAGCGCGAGGTGCTC
GGTCTGATAGCCGACGGCCGCTCCAACCGCGAGATCGCCCGCGCGCTGGTCCTCTCCGAGAAGACGGTGAAGACCCACGT
CTCGAACATCCTGATGAAGCTCGACCTGGCGGACCGTACACAGGCCGCGCTGTGGGCGGTACGCAACGGTGTGGCCGGAT
GA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-118)

Bacterial regulatory proteins, luxR family (GerE)

(151-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

46.226

99.531

0.46
  degU Bacillus subtilis subsp. subtilis str. 168

38.914

100

0.404