Detailed information NTG0647462

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: L1O91_RS12975
• Genome accession: NZ_CP091066
• Coordinates: 2635342..2636229 (-)
• Length: 295 a.a.
• NCBI ID: WP_054189713.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain UMCG579
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2630342..2641229

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
L1O91_RS12945 (L1O91_12945)	-	2630349..2630441 (+)	93	WP_054189707.1	hypothetical protein	-
L1O91_RS12950 (L1O91_12950)	-	2630549..2631046 (-)	498	WP_054189708.1	glutathione peroxidase	-
L1O91_RS12955 (L1O91_12955)	-	2631056..2631316 (-)	261	WP_077446674.1	hypothetical protein	-
L1O91_RS12960 (L1O91_12960)	-	2631740..2631823 (-)	84	Protein_2512	hypothetical protein	-
L1O91_RS12965 (L1O91_12965)	-	2632481..2634481 (-)	2001	WP_054189711.1	ABC transporter permease	-
L1O91_RS12970 (L1O91_12970)	-	2634478..2635233 (-)	756	WP_054189712.1	ABC transporter ATP-binding protein	-
L1O91_RS12975 (L1O91_12975)	braS	2635342..2636229 (-)	888	WP_054189713.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
L1O91_RS12980 (L1O91_12980)	braR	2636240..2636905 (-)	666	WP_054189714.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
L1O91_RS12985 (L1O91_12985)	-	2636931..2637131 (-)	201	WP_054189715.1	hypothetical protein	-
L1O91_RS12990 (L1O91_12990)	-	2637329..2638753 (+)	1425	WP_054189717.1	alkaline phosphatase	-
L1O91_RS13480	-	2638813..2638914 (-)	102	WP_070016594.1	SE2200 family small protein	-
L1O91_RS13000 (L1O91_13000)	-	2639035..2639490 (-)	456	WP_054189718.1	MarR family winged helix-turn-helix transcriptional regulator	-
L1O91_RS13005 (L1O91_13005)	-	2639735..2640496 (-)	762	WP_054189719.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34080.47 Da
• Isoelectric Point: 6.7607

>NTDB_id=647462 L1O91_RS12975 WP_054189713.1 2635342..2636229(-) (braS) [Staphylococcus aureus strain UMCG579]
MTFLKSIIQEIAIVIVIFALFGLMFYLYRLPLEAYLLALGVISLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFNEQSNQLYIKDNGMGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDK

Nucleotide

• Length: 888 bp

>NTDB_id=647462 L1O91_RS12975 WP_054189713.1 2635342..2636229(-) (braS) [Staphylococcus aureus strain UMCG579]
ATGACCTTTCTTAAAAGTATTATTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCGTTTGCCATTAGAAGCGTATTTACTAGCACTTGGCGTTATTTCATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAACCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAATTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAACTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTAATGAACAATCTAATCAATTATATATAAAAGATAATGGTATGGGTATTAGTGAAGCAGACTTGCCTAAA
ATATTTGATAAAGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCATACAAACCATCCTGTTTCAGTCGTGTCTAAACAAAATGAGGGTACAACTTTTACGATTCAATTTCCAG
ATAAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	96.949	100	0.969