Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHN73_RS12770 Genome accession   NZ_CP107839
Coordinates   2741357..2742040 (-) Length   227 a.a.
NCBI ID   WP_266522512.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00519     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2736357..2747040
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHN73_RS12745 (OHN73_12650) - 2736704..2737582 (-) 879 WP_266522523.1 ABC transporter permease -
  OHN73_RS12750 (OHN73_12655) - 2737572..2738387 (-) 816 WP_328549980.1 ABC transporter ATP-binding protein -
  OHN73_RS12755 (OHN73_12660) - 2738549..2739057 (+) 509 Protein_2545 response regulator -
  OHN73_RS12760 (OHN73_12665) - 2739132..2740724 (-) 1593 WP_266522517.1 cation acetate symporter -
  OHN73_RS12765 (OHN73_12670) - 2740721..2741287 (-) 567 WP_328549981.1 DUF485 domain-containing protein -
  OHN73_RS12770 (OHN73_12675) vraR 2741357..2742040 (-) 684 WP_266522512.1 response regulator transcription factor Regulator
  OHN73_RS12775 (OHN73_12680) - 2742037..2743188 (-) 1152 WP_328549982.1 histidine kinase -
  OHN73_RS12780 (OHN73_12685) - 2743185..2743709 (-) 525 WP_266522508.1 CcdC protein domain-containing protein -
  OHN73_RS12785 (OHN73_12690) - 2744229..2746349 (-) 2121 WP_266522506.1 type IIA DNA topoisomerase subunit B -
  OHN73_RS12790 (OHN73_12695) - 2746792..2747022 (+) 231 WP_266522504.1 hypothetical protein -

Sequence

Protein


Download         Length: 227 a.a.        Molecular weight: 24147.64 Da        Isoelectric Point: 4.8577

>NTDB_id=646800 OHN73_RS12770 WP_266522512.1 2741357..2742040(-) (vraR) [Streptomyces sp. NBC_00519]
MTEGAETRPARVVVADDQTVVREGIVMLLGLLPGIEVVGAAGDGDEAVQLVAELAPDVVLMDLRMPRCDGVEATRRIRAE
HPGTQVVVLTTYADDESLFPALRAGARGYLTKDAGGDEIVRAVQSVLSGDAGLSPSIQRRLLERLSDPEPPPATIMEAPD
GLTARETEVLLLIAEGLSNQEIARKLHVSTATVKTHINNLFAKTGLKDRAQAVRYAYAKGLARPPVG

Nucleotide


Download         Length: 684 bp        

>NTDB_id=646800 OHN73_RS12770 WP_266522512.1 2741357..2742040(-) (vraR) [Streptomyces sp. NBC_00519]
ATGACGGAAGGGGCGGAGACGCGGCCCGCGCGCGTGGTCGTCGCGGACGACCAGACCGTCGTGCGTGAGGGCATCGTGAT
GCTGCTGGGCCTGCTGCCCGGGATCGAGGTGGTCGGCGCCGCGGGCGACGGGGACGAGGCGGTGCAGCTTGTCGCCGAGC
TCGCCCCGGACGTGGTGCTGATGGACCTGCGTATGCCCCGCTGTGACGGTGTGGAGGCGACCCGGCGCATTCGTGCCGAG
CACCCCGGGACGCAAGTCGTGGTGCTCACGACGTACGCGGACGACGAGTCCTTGTTCCCGGCGTTGCGGGCGGGGGCACG
GGGTTATCTCACCAAGGACGCGGGAGGGGACGAGATCGTACGGGCCGTGCAGAGTGTGCTGTCCGGGGACGCGGGGCTGT
CGCCCAGCATCCAACGGCGGTTGCTGGAGCGGCTGTCCGATCCGGAGCCGCCGCCGGCGACCATCATGGAGGCGCCGGAC
GGGCTCACAGCACGGGAGACGGAGGTGCTGCTGCTGATCGCCGAAGGCCTCAGTAACCAGGAAATCGCCCGGAAGCTGCA
TGTCTCCACCGCGACCGTGAAGACCCACATCAACAACCTCTTCGCCAAGACCGGGCTCAAGGATCGCGCCCAGGCGGTGC
GTTACGCGTATGCGAAGGGGCTTGCGCGGCCGCCGGTGGGGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(12-123)

Bacterial regulatory proteins, luxR family (GerE)

(161-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.336

92.952

0.366