Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHS17_RS18185 Genome accession   NZ_CP107836
Coordinates   4017983..4018648 (-) Length   221 a.a.
NCBI ID   WP_330313011.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00523     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4012983..4023648
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHS17_RS18155 (OHS17_18180) - 4013384..4014091 (-) 708 WP_330315287.1 rhomboid-like protein -
  OHS17_RS18160 (OHS17_18185) - 4014125..4015069 (+) 945 WP_330313007.1 aminoglycoside phosphotransferase family protein -
  OHS17_RS18165 (OHS17_18190) - 4015101..4015577 (+) 477 WP_073862380.1 GNAT family N-acetyltransferase -
  OHS17_RS18170 (OHS17_18195) - 4015608..4016597 (-) 990 WP_330313008.1 zinc-binding dehydrogenase -
  OHS17_RS18175 (OHS17_18200) - 4016711..4017391 (+) 681 WP_330313009.1 pentapeptide repeat-containing protein -
  OHS17_RS18180 (OHS17_18205) - 4017452..4017949 (-) 498 WP_330313010.1 hypothetical protein -
  OHS17_RS18185 (OHS17_18210) vraR 4017983..4018648 (-) 666 WP_330313011.1 response regulator transcription factor Regulator
  OHS17_RS18190 (OHS17_18215) - 4018645..4019880 (-) 1236 WP_330313012.1 sensor histidine kinase -
  OHS17_RS18195 (OHS17_18220) - 4020108..4020665 (+) 558 WP_330313013.1 heme-binding protein -
  OHS17_RS18200 (OHS17_18225) - 4020697..4021311 (+) 615 WP_330313014.1 ankyrin repeat domain-containing protein -
  OHS17_RS18205 (OHS17_18230) - 4021365..4022462 (+) 1098 WP_330315288.1 hypothetical protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 23364.70 Da        Isoelectric Point: 5.7145

>NTDB_id=646749 OHS17_RS18185 WP_330313011.1 4017983..4018648(-) (vraR) [Streptomyces sp. NBC_00523]
MSADPTADVTAGPTADRIRILLCDDHAVVRAGLLALLGSEPDIEVIGEAGSGEEAVALATRLTPDVVLMDLQLGSGIDGV
EATRRIAAGPGTHVLVLTTYDTDADITRAIEAGATGYLLKAERPEELFAAIRSAAQGRTTLSPPVASRVMARMRAPRHTL
TDRERDILGQLSRGLGNREIARALFISEATVKTHLGRIYDKLGVDTRAGAVAVAKEQRLLP

Nucleotide


Download         Length: 666 bp        

>NTDB_id=646749 OHS17_RS18185 WP_330313011.1 4017983..4018648(-) (vraR) [Streptomyces sp. NBC_00523]
ATGAGCGCCGACCCGACCGCCGACGTCACCGCGGGCCCGACCGCGGACCGCATCCGCATCCTGCTCTGCGACGACCACGC
CGTCGTACGCGCCGGGCTCCTCGCCCTCCTCGGCAGCGAGCCCGACATCGAGGTCATCGGCGAGGCGGGCAGCGGCGAGG
AGGCCGTCGCGCTCGCCACCCGGCTCACCCCGGACGTCGTCCTGATGGACCTCCAGCTGGGCAGCGGCATCGACGGCGTC
GAAGCTACCCGTCGCATCGCGGCCGGGCCCGGCACCCACGTCCTCGTCCTCACCACGTACGACACCGACGCCGACATCAC
GCGCGCCATCGAGGCGGGCGCCACCGGCTACCTGCTCAAGGCCGAACGCCCCGAGGAGCTGTTCGCCGCGATCCGCTCCG
CCGCCCAGGGCCGCACCACGCTCTCCCCGCCCGTCGCCAGCCGCGTGATGGCCCGCATGCGCGCACCCCGCCACACCCTC
ACCGACCGCGAACGCGACATCCTCGGCCAGCTCTCCCGGGGCCTCGGCAACCGCGAGATCGCCCGCGCCCTGTTCATCAG
CGAGGCCACGGTCAAGACGCACCTGGGGCGCATCTACGACAAGCTCGGCGTCGACACCCGCGCGGGCGCCGTCGCCGTCG
CCAAGGAGCAGCGGCTGCTGCCGTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(20-132)

Bacterial regulatory proteins, luxR family (GerE)

(159-214)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40.097

93.665

0.376