Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHS33_RS19895 Genome accession   NZ_CP107819
Coordinates   4518875..4519531 (-) Length   218 a.a.
NCBI ID   WP_330331753.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00536     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4513875..4524531
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHS33_RS19870 (OHS33_19870) - 4514133..4515070 (+) 938 Protein_3902 aminoglycoside phosphotransferase family protein -
  OHS33_RS19875 (OHS33_19875) - 4515151..4515654 (+) 504 WP_330331749.1 GNAT family N-acetyltransferase -
  OHS33_RS19880 (OHS33_19880) - 4515684..4516343 (+) 660 WP_330331750.1 pentapeptide repeat-containing protein -
  OHS33_RS19885 (OHS33_19885) - 4516374..4516877 (-) 504 WP_330331751.1 hypothetical protein -
  OHS33_RS19890 (OHS33_19890) - 4516980..4518512 (-) 1533 WP_330331752.1 M4 family metallopeptidase -
  OHS33_RS19895 (OHS33_19895) vraR 4518875..4519531 (-) 657 WP_330331753.1 response regulator transcription factor Regulator
  OHS33_RS19900 (OHS33_19900) - 4519528..4520799 (-) 1272 WP_330331754.1 sensor histidine kinase -
  OHS33_RS19905 (OHS33_19905) - 4521192..4521722 (+) 531 WP_330331755.1 heme-binding protein -
  OHS33_RS19910 (OHS33_19910) - 4521776..4523245 (+) 1470 WP_330331756.1 M1 family metallopeptidase -
  OHS33_RS19915 (OHS33_19915) - 4523229..4523762 (-) 534 WP_330331757.1 GNAT family N-acetyltransferase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 22884.34 Da        Isoelectric Point: 5.3124

>NTDB_id=646596 OHS33_RS19895 WP_330331753.1 4518875..4519531(-) (vraR) [Streptomyces sp. NBC_00536]
MTPPTPTPPTTILLCDDHLVVRAGLLALLGSEPDIEVVGEAGSGEEAVALAAALRPDVVLMDLQLGEGIDGIEATRRIAA
LPGPPAPPHVLVLTTYDTDADITRAIGAGATGYLLKAERPEELFAAIHSAAQGRTTLSPPVASRVMAHMRGTKPTLTERE
LDILGQLARGLGNRDIARALFISEATVKTHLGRIYDKLGVDTRTGAVSVAKEQRLLPS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=646596 OHS33_RS19895 WP_330331753.1 4518875..4519531(-) (vraR) [Streptomyces sp. NBC_00536]
ATGACCCCGCCGACCCCCACCCCTCCCACCACGATCCTGCTCTGCGACGACCACCTGGTCGTCCGGGCCGGCCTGCTCGC
CCTCCTCGGCAGCGAGCCGGACATCGAGGTGGTCGGCGAGGCGGGCAGCGGCGAGGAAGCGGTGGCCCTGGCGGCCGCGC
TGCGGCCCGACGTCGTCCTGATGGACCTCCAGCTCGGCGAGGGCATCGACGGGATCGAGGCCACCCGCCGCATCGCCGCG
CTCCCGGGGCCACCCGCCCCGCCGCACGTCCTGGTGCTGACGACGTACGACACGGACGCCGACATCACGCGCGCCATCGG
CGCGGGCGCCACCGGGTACCTGCTGAAGGCGGAGCGGCCCGAGGAACTCTTCGCCGCCATCCACTCCGCCGCCCAGGGCC
GCACCACGCTCTCCCCGCCGGTGGCCAGCCGGGTGATGGCCCACATGCGCGGTACGAAGCCCACCCTGACGGAGCGTGAA
CTGGACATCCTGGGTCAGCTCGCCCGTGGCCTGGGCAACCGGGACATCGCCCGCGCCCTGTTCATCAGCGAGGCCACCGT
CAAGACCCACCTGGGCCGGATCTACGACAAGCTCGGCGTCGACACGCGCACGGGCGCCGTCTCGGTGGCCAAGGAGCAGC
GCCTCCTGCCGTCCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(12-127)

Bacterial regulatory proteins, luxR family (GerE)

(155-210)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40

96.33

0.385