Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHA33_RS22130 Genome accession   NZ_CP107791
Coordinates   4915866..4916492 (-) Length   208 a.a.
NCBI ID   WP_326628428.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00562     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4910866..4921492
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHA33_RS22100 (OHA33_22155) - 4911492..4911632 (+) 141 Protein_4348 hydroxyurea phosphotransferase -
  OHA33_RS22105 (OHA33_22160) - 4911688..4912161 (+) 474 WP_330245687.1 GNAT family N-acetyltransferase -
  OHA33_RS22110 (OHA33_22165) - 4912179..4913180 (-) 1002 WP_330245688.1 zinc-binding dehydrogenase -
  OHA33_RS22115 (OHA33_22170) - 4913227..4914426 (-) 1200 WP_330245689.1 NAD(P)-binding protein -
  OHA33_RS22120 (OHA33_22175) - 4914526..4915227 (+) 702 WP_330245690.1 pentapeptide repeat-containing protein -
  OHA33_RS22125 (OHA33_22180) - 4915255..4915752 (-) 498 WP_267003488.1 hypothetical protein -
  OHA33_RS22130 (OHA33_22185) vraR 4915866..4916492 (-) 627 WP_326628428.1 response regulator transcription factor Regulator
  OHA33_RS22135 (OHA33_22190) - 4916489..4917748 (-) 1260 WP_330245691.1 sensor histidine kinase -
  OHA33_RS22140 (OHA33_22195) - 4918000..4918557 (+) 558 WP_330245692.1 heme-binding protein -
  OHA33_RS22145 (OHA33_22200) - 4918590..4919192 (+) 603 WP_330245693.1 ankyrin repeat domain-containing protein -
  OHA33_RS22150 (OHA33_22205) - 4919240..4920640 (+) 1401 WP_330245694.1 M1 family metallopeptidase -

Sequence

Protein


Download         Length: 208 a.a.        Molecular weight: 22082.40 Da        Isoelectric Point: 5.1096

>NTDB_id=646277 OHA33_RS22130 WP_326628428.1 4915866..4916492(-) (vraR) [Streptomyces sp. NBC_00562]
MTPPAVRILLCDDHAVVRAGLLALLGSEPDIEVVGEAGSGEEAVALAARLTPDVVLMDLQLGEGIDGVEATRRIAVTGVH
VLVLTTYDTDADITRAIEAGATGYLLKAERPEELFAAIRSAAQGRTTLSPPVASRVMARMRSPLPTLTDRERDILGQLSQ
GLGNREIARALFISEATVKTHLGRIYDKLGVDTRAGAVSVAKEQRLLP

Nucleotide


Download         Length: 627 bp        

>NTDB_id=646277 OHA33_RS22130 WP_326628428.1 4915866..4916492(-) (vraR) [Streptomyces sp. NBC_00562]
ATGACCCCGCCCGCCGTACGGATCCTGCTCTGCGACGACCACGCCGTCGTACGCGCCGGACTGCTCGCCCTCCTGGGCAG
CGAACCGGACATCGAGGTCGTCGGCGAGGCGGGCAGCGGCGAGGAGGCCGTCGCCCTGGCCGCCCGGCTGACCCCGGACG
TCGTCCTGATGGACCTCCAGCTGGGCGAAGGAATCGACGGCGTCGAAGCCACCCGCCGCATCGCGGTCACCGGCGTCCAT
GTCCTCGTCCTCACGACGTACGACACGGACGCCGACATCACCCGCGCCATCGAAGCGGGCGCCACCGGCTACCTGCTGAA
GGCGGAACGCCCGGAGGAACTGTTCGCCGCGATCCGCTCGGCGGCCCAGGGCCGCACCACGCTCTCCCCGCCGGTTGCCA
GCCGTGTCATGGCCCGCATGCGCAGCCCCCTGCCGACGCTCACGGACCGCGAACGCGACATCCTGGGCCAGCTGTCCCAG
GGCCTGGGCAACCGGGAGATCGCCCGGGCCCTGTTCATCAGCGAGGCCACGGTCAAGACGCACCTGGGCCGCATCTACGA
CAAACTCGGCGTCGACACCCGCGCGGGCGCCGTGTCCGTGGCGAAGGAGCAGCGGCTGCTGCCGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(8-119)

Bacterial regulatory proteins, luxR family (GerE)

(146-201)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40.097

99.519

0.399
  degU Bacillus subtilis subsp. subtilis str. 168

35.78

100

0.375