Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHA33_RS21670 Genome accession   NZ_CP107791
Coordinates   4812986..4813648 (+) Length   220 a.a.
NCBI ID   WP_330245634.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00562     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4807986..4818648
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHA33_RS21650 (OHA33_21705) - 4808474..4809322 (+) 849 WP_326604967.1 tryptophan 2,3-dioxygenase family protein -
  OHA33_RS21655 (OHA33_21710) kynU 4809315..4810553 (+) 1239 WP_330245632.1 kynureninase -
  OHA33_RS21660 (OHA33_21715) - 4810663..4811538 (+) 876 WP_326814762.1 alpha/beta hydrolase -
  OHA33_RS21665 (OHA33_21720) - 4811670..4812989 (+) 1320 WP_330245633.1 histidine kinase -
  OHA33_RS21670 (OHA33_21725) vraR 4812986..4813648 (+) 663 WP_330245634.1 response regulator transcription factor Regulator
  OHA33_RS21675 (OHA33_21730) - 4813686..4814915 (+) 1230 WP_330245635.1 cytochrome P450 -
  OHA33_RS21680 (OHA33_21735) - 4815056..4816657 (-) 1602 WP_330245636.1 ABC transporter permease -
  OHA33_RS21685 (OHA33_21740) - 4816654..4817577 (-) 924 WP_330245637.1 ABC transporter ATP-binding protein -
  OHA33_RS21690 (OHA33_21745) - 4817803..4818225 (+) 423 WP_330248921.1 MarR family transcriptional regulator -
  OHA33_RS21695 (OHA33_21750) - 4818270..4818542 (-) 273 WP_267003640.1 DUF1876 domain-containing protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23533.37 Da        Isoelectric Point: 4.9350

>NTDB_id=646274 OHA33_RS21670 WP_330245634.1 4812986..4813648(+) (vraR) [Streptomyces sp. NBC_00562]
MNDIRVLIVDDQMMVREGFSVLLGAMPGIEVVGEAVDGRQAIAQAAALRPDVVLMDIRMPELNGIEATREIVANDAAAKV
LVLTTFDLDEYVYQALRAGASGFLLKDASARQLADGVRVVAAGEALLAPIVTKRLITEFSRLAGAPRPPALARIGDLTER
ETEVLVLIAQGLSNAEIASHLVVAESTIKTHVSRILVKLGLRDRTQAAVFAYEARLVTPA

Nucleotide


Download         Length: 663 bp        

>NTDB_id=646274 OHA33_RS21670 WP_330245634.1 4812986..4813648(+) (vraR) [Streptomyces sp. NBC_00562]
ATGAACGACATCCGTGTCCTGATCGTCGACGACCAGATGATGGTCCGCGAGGGCTTCTCGGTGCTCCTGGGGGCGATGCC
GGGCATCGAGGTCGTCGGCGAGGCCGTCGACGGCCGGCAGGCCATCGCCCAGGCGGCCGCGCTGCGGCCCGACGTGGTGC
TGATGGACATCCGGATGCCGGAGCTCAACGGCATCGAGGCGACCCGTGAGATCGTCGCGAACGACGCGGCCGCCAAGGTG
CTCGTGCTGACCACGTTCGACCTCGACGAGTACGTGTACCAGGCGCTGCGCGCCGGGGCGTCCGGGTTTCTGCTGAAGGA
CGCCTCCGCCCGCCAGCTCGCCGACGGGGTACGGGTGGTGGCGGCCGGGGAGGCGCTGCTGGCGCCGATCGTCACGAAGC
GGCTGATCACCGAGTTCTCCCGGCTCGCGGGGGCCCCGCGGCCGCCCGCGCTCGCCCGGATCGGCGATCTGACGGAGCGC
GAGACGGAGGTGCTCGTACTCATCGCGCAGGGCCTGTCGAACGCGGAGATCGCCTCGCACCTGGTGGTCGCCGAGTCCAC
CATCAAGACGCATGTGAGCCGCATCCTGGTGAAGCTGGGGCTGCGGGACCGTACGCAGGCGGCGGTGTTCGCGTACGAGG
CGCGGCTGGTCACCCCGGCCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(6-115)

Bacterial regulatory proteins, luxR family (GerE)

(157-211)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.86

97.273

0.436
  degU Bacillus subtilis subsp. subtilis str. 168

42.727

100

0.427