Detailed information NTG0064611

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: SPYOHK_RS01055
• Genome accession: NZ_AFRY01000001
• Coordinates: 1664706..1665776 (-)
• Length: 356 a.a.
• NCBI ID: WP_002986002.1
• Uniprot ID: Q1JNF7
• Organism: Streptococcus pyogenes HKU QMH11M0907901
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1659706..1670776

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPYOHK_RS01065 (SPYOHK_08220)	-	1663462..1663641 (+)	180	WP_100215900.1	transposase	-
SPYOHK_RS10340	-	1663668..1663805 (+)	138	Protein_1600	IS3 family transposase	-
SPYOHK_RS01060 (SPYOHK_08225)	amiF	1663790..1664713 (-)	924	WP_002986000.1	ABC transporter ATP-binding protein	Regulator
SPYOHK_RS01055 (SPYOHK_08230)	amiE	1664706..1665776 (-)	1071	WP_002986002.1	ABC transporter ATP-binding protein	Regulator
SPYOHK_RS01050 (SPYOHK_08235)	amiD	1665785..1666711 (-)	927	WP_002986004.1	oligopeptide ABC transporter permease OppC	Regulator
SPYOHK_RS01045 (SPYOHK_08240)	amiC	1666711..1668213 (-)	1503	WP_002991105.1	ABC transporter permease	Regulator
SPYOHK_RS01040 (SPYOHK_08245)	amiA	1668278..1670248 (-)	1971	WP_024623426.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 356 a.a.
• Molecular weight: 39749.85 Da
• Isoelectric Point: 5.7015

>NTDB_id=64611 SPYOHK_RS01055 WP_002986002.1 1664706..1665776(-) (amiE) [Streptococcus pyogenes HKU QMH11M0907901]
MTKENNVILTAKDVVVEFDVRDRVLTAIRNVSLELVEGEVLAFVGESGSGKSVLTKTFTGMLESNGRIANGSIVYRGQEL
TDLKTNKEWAKIRGSKIATIFQDPMTSLSPIKTIGRQITEVIIKHQKVSNAKAKEMALDYMNKVGIPNAKKRFEDYPFEY
SGGMRQRIVIAIALACRPDILICDEPTTALDVTIQAQIVELLKSLQREYHFTIIFITHDLGVVASIADKVAVMYAGEIVE
FGTVEEIFYDPRHPYTWSLLSSLPQLADESGELYAIPGTPPSLYSPIIGDAFALRSEYAMVLDFEKAPPAINVSETHWAK
TWLLHPEAPKVQKPEVIQDLHQKILRKMSQQEEGNV

Nucleotide

• Length: 1071 bp

>NTDB_id=64611 SPYOHK_RS01055 WP_002986002.1 1664706..1665776(-) (amiE) [Streptococcus pyogenes HKU QMH11M0907901]
ATGACAAAAGAAAATAATGTAATCTTAACTGCCAAAGATGTGGTGGTAGAATTTGATGTGCGTGATCGTGTTTTAACAGC
TATCCGTAACGTCTCACTGGAACTTGTTGAAGGAGAAGTCCTTGCTTTTGTAGGGGAATCAGGCTCAGGTAAATCTGTTT
TAACAAAGACCTTTACAGGGATGTTGGAGTCTAATGGACGCATTGCTAATGGTTCAATTGTCTATCGTGGGCAAGAATTG
ACAGATTTAAAAACAAATAAAGAGTGGGCAAAGATTCGCGGCTCAAAAATCGCAACGATTTTCCAAGACCCAATGACCAG
TCTTAGTCCCATTAAAACTATCGGTAGACAAATCACAGAAGTGATTATTAAGCACCAAAAAGTAAGTAATGCCAAAGCTA
AAGAAATGGCCCTTGATTACATGAATAAAGTGGGTATCCCAAATGCCAAAAAACGCTTTGAAGATTACCCATTTGAGTAT
TCAGGAGGAATGCGTCAACGTATTGTTATCGCTATTGCTTTAGCTTGTCGCCCAGATATTCTTATCTGTGATGAGCCAAC
AACAGCCCTTGATGTGACTATTCAAGCTCAAATCGTTGAGTTATTGAAGTCGCTTCAACGAGAATATCATTTCACCATTA
TCTTTATTACGCACGATTTAGGTGTTGTGGCAAGCATTGCAGATAAAGTGGCTGTCATGTATGCAGGAGAAATTGTTGAA
TTTGGAACAGTCGAAGAGATTTTCTATGATCCAAGACACCCCTATACATGGAGTTTGCTGTCTAGCTTACCGCAGTTGGC
AGATGAATCTGGTGAACTTTACGCTATTCCAGGAACGCCTCCATCACTTTATTCACCAATTATCGGAGATGCCTTTGCAC
TTCGCTCAGAATATGCTATGGTTTTAGACTTTGAAAAAGCACCTCCGGCGATTAACGTATCTGAGACTCATTGGGCCAAA
ACATGGCTTTTACACCCAGAGGCTCCAAAAGTTCAAAAACCAGAAGTCATTCAAGATTTGCATCAAAAAATCTTAAGGAA
AATGTCACAACAGGAGGAAGGAAATGTCTGA

Domains

Predicted by InterproScan.

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-299)

• ABC transporter (ABC_tran) (29-187)

3D structure

• AlphaFold DB: Q1JNF7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	76.389	100	0.772
amiE	Streptococcus thermophilus LMG 18311	75.278	100	0.761
amiE	Streptococcus thermophilus LMD-9	75.278	100	0.761
oppD	Streptococcus mutans UA159	56.677	94.663	0.537