Detailed information NTG0645825

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: L1A16_RS04165
• Genome accession: NZ_CP090885
• Coordinates: 831018..833258 (+)
• Length: 746 a.a.
• NCBI ID: WP_000942395.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain ND6401
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 826018..838258

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
L1A16_RS04135 (L1A16_04135)	-	826168..827136 (+)	969	WP_000658183.1	PhoH family protein	-
L1A16_RS04140 (L1A16_04140)	-	827329..827829 (+)	501	WP_000566988.1	GNAT family N-acetyltransferase	-
L1A16_RS04145 (L1A16_04145)	-	827832..828158 (+)	327	Protein_827	TfoX/Sxy family protein	-
L1A16_RS04150 (L1A16_04150)	ald	828459..829570 (-)	1112	Protein_828	alanine dehydrogenase	-
L1A16_RS04155 (L1A16_04155)	-	829747..830316 (+)	570	WP_000443747.1	GNAT family N-acetyltransferase	-
L1A16_RS04160 (L1A16_04160)	comEA/celA/cilE	830384..831034 (+)	651	WP_000387330.1	ComEA family DNA-binding protein	Machinery gene
L1A16_RS04165 (L1A16_04165)	comEC/celB	831018..833258 (+)	2241	WP_000942395.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
L1A16_RS04170 (L1A16_04170)	-	833437..833625 (+)	189	WP_001809102.1	hypothetical protein	-
L1A16_RS04175 (L1A16_04175)	-	833657..834244 (+)	588	WP_000933542.1	ABC transporter ATP-binding protein	-
L1A16_RS04180 (L1A16_04180)	-	834248..835429 (+)	1182	WP_000655956.1	hypothetical protein	-
L1A16_RS04185 (L1A16_04185)	infC	835736..836266 (+)	531	WP_000848180.1	translation initiation factor IF-3	-
L1A16_RS04190 (L1A16_04190)	rpmI	836299..836499 (+)	201	WP_001125943.1	50S ribosomal protein L35	-
L1A16_RS04195 (L1A16_04195)	rplT	836551..836910 (+)	360	WP_000124836.1	50S ribosomal protein L20	-
L1A16_RS04200 (L1A16_04200)	-	836968..837348 (+)	381	WP_000157154.1	VOC family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84600.12 Da
• Isoelectric Point: 9.3408

>NTDB_id=645825 L1A16_RS04165 WP_000942395.1 831018..833258(+) (comEC/celB) [Streptococcus pneumoniae strain ND6401]
MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCLFIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQASQN
LADSVERVRILPDTIKVNGDSLSFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLLGHLDTDFEEMNELYSSLGIIHL
FALSGMQVGFFMNGFKKLLLQLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIV
MPNFFLTAGGVLSCAYAFILTMTSKEGEGLKAVASESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDLTFLPLLSI
LFVLSFLYPVIQLNFIFEWLEGIIRLVSQVTSRPLVFGQPNAWFLILLLISLALVYDLRKNIKKLTVLCLLITGLFLLTK
HPLENEITMLDVGQGESIFLRDVTGKTILIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVVKIDQLILTNTDK
EHVGDLSEVTKAFHVGEILVSKDSLKQKEFVAELQVTQTKVRSMTVGEYLPIFGSQLEVLSPREIGYGGHEDSLVLYGKL
LNNHFLFIGNLEEKGEKDLLKYYPDLKVNVLKASQHGNKKSSSPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGIN
SKVYRTDQQGAIRFKGLDSWKIESVR

Nucleotide

• Length: 2241 bp

>NTDB_id=645825 L1A16_RS04165 WP_000942395.1 831018..833258(+) (comEC/celB) [Streptococcus pneumoniae strain ND6401]
ATGTTACAGTGGATTAAGAATTTCTCTATTCCCCTAATTTACCTGAGTTTTCTATTACTTTGGCTTTATTACGCTATTTT
CTCAGCATCTTATCTTGCTTTGTTGGGCTTTGTTTTTCTGCTAGTCTGTCTCTTTATCCAATTTCCGTGGAAATCTGCTG
GTAAAGTTCTAATAATTTGCGGAATCTTTGGATTTTGGTTTGTTTTTCAAAATTGGCAACAGAGTCAAGCGAGTCAAAAT
CTGGCGGATTCTGTTGAAAGGGTACGGATTTTGCCTGATACTATTAAGGTTAATGGTGATAGTCTATCCTTTCGTGGCAA
GTCTAACGGTCGTGCTTTCCAAGTCTATTATAAACTCCAGTCCGAGGAGGAGAAAGAAGCCTTTCAAGCTTTAACCGACC
TGCATGAGATAGGACTAGAAGGGAAGCTTTCGGAGCCAGAAGGGCAGAGAAATTTTGGTGGCTTTAATTACCAAGCCTAT
CTGAAGACTCAGGGAATTTACCAGACTCTCAATATCAAAACAATCCAGTCACTTCAAAAGATTGGCAGTTGGGATATAGG
AGAAAACTTGTCCAGTTTACGTCGAAAGGCTGTGGTTTGGATTAAGACGCACTTTCCAGACCCTATGCGCAATTACATGA
CAGGACTCTTGCTGGGACATCTGGACACCGACTTTGAGGAGATGAATGAGCTTTATTCCAGTCTAGGAATTATCCACCTC
TTTGCCCTATCTGGCATGCAGGTAGGTTTTTTCATGAATGGATTTAAGAAACTTCTCTTGCAATTGGGCTTGACCCAAGA
AAAGTTGAAATGGCTGACTTATCCCTTTTCCCTTATCTATGCGGGACTAACTGGATTTTCAGCATCGGTTATTCGCAGTC
TCTTGCAAAAGCTACTGGCTCAACATGGGGTTAAGGGCTTGGATAATTTTGCCTTGACGGTGCTTGTCCTCTTTATTGTC
ATGCCAAACTTTTTCTTGACAGCAGGAGGAGTCTTGTCCTGCGCTTATGCTTTTATCCTGACCATGACCAGCAAAGAAGG
GGAGGGGCTCAAGGCTGTTGCTAGTGAAAGTCTAGTCATCTCCTTGGGCATATTGCCCATTCTATCCTTCTATTTTGCGG
AATTTCAACCTTGGTCTATCCTTTTGACCTTTGTCTTTTCCTTTCTATTTGACTTGACCTTCTTACCGCTCTTGTCTATT
TTATTTGTCCTTTCCTTTCTCTATCCAGTCATTCAGCTGAACTTTATCTTTGAATGGTTGGAGGGCATTATTCGCTTGGT
GTCACAGGTGACAAGTAGACCTCTGGTCTTTGGACAACCCAATGCATGGTTTTTAATCCTATTGTTAATTTCCTTGGCTT
TGGTCTATGATTTGAGAAAAAACATTAAAAAGCTAACGGTATTGTGCTTATTGATTACAGGGCTCTTTCTCCTGACCAAG
CATCCACTGGAAAATGAAATCACCATGCTGGATGTGGGGCAAGGAGAAAGTATTTTCCTACGGGATGTAACTGGGAAAAC
CATTCTCATAGATGTAGGTGGTAAGGCAGAATCTTATAAGAAAATCGAAAAATGGCAAGAAAAGATGACGACCAGCAATG
CCCAGCGAACCTTGATTCCCTATCTCAAAAGTCGAGGAGTAGTTAAGATTGACCAGCTAATTTTGACTAACACGGACAAG
GAGCATGTTGGAGATTTGTCAGAGGTGACTAAGGCTTTCCATGTAGGGGAGATTCTAGTATCAAAAGACAGTCTGAAACA
GAAGGAATTTGTGGCAGAACTACAGGTGACTCAAACAAAGGTGCGTAGTATGACAGTAGGGGAGTACTTGCCCATTTTCG
GAAGTCAGTTAGAAGTCCTATCTCCAAGGGAAATTGGATATGGAGGTCATGAAGATTCCCTGGTTCTTTATGGGAAACTC
TTGAATAATCACTTTCTCTTCATAGGAAATTTGGAGGAGAAAGGAGAGAAGGACTTGCTGAAGTATTATCCAGACTTGAA
AGTAAATGTTTTGAAAGCTAGCCAACATGGCAATAAAAAATCATCAAGTCCAGCCTTTCTAGAAAAACTCAAACCAGAGC
TTACTCTTATCTCAGTTGGAAAGAGCAATCGAATGAAACTCCCCCATCAGGAAACATTGACACGACTGGAAGGTATCAAT
AGCAAAGTTTATCGAACTGACCAGCAAGGAGCTATACGTTTTAAGGGGTTGGATAGTTGGAAAATCGAAAGTGTTCGATA
G

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (30-176)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-632)

• Competence protein (Competence) (216-458)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus pneumoniae TIGR4	96.247	100	0.962
comEC/celB	Streptococcus pneumoniae D39	96.247	100	0.962
comEC/celB	Streptococcus pneumoniae R6	96.247	100	0.962
comEC/celB	Streptococcus pneumoniae Rx1	96.247	100	0.962
comEC/celB	Streptococcus mitis NCTC 12261	91.544	99.866	0.914
comEC/celB	Streptococcus mitis SK321	91.287	100	0.913
comEC	Lactococcus lactis subsp. cremoris KW2	43.86	99.33	0.436