Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   SPB_RS10500 Genome accession   NZ_AEUT02000001
Coordinates   2079511..2081955 (+) Length   814 a.a.
NCBI ID   WP_003102418.1    Uniprot ID   A0A1S1ZRW2
Organism   Streptococcus parauberis NCFD 2020     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 2074511..2086955
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPB_RS10475 (SPB_2161) - 2074940..2075899 (-) 960 WP_003104770.1 VOC family protein -
  SPB_RS10480 (SPB_2162) - 2076001..2078073 (-) 2073 WP_003103075.1 sodium:proton antiporter -
  SPB_RS10485 (SPB_2163) - 2078075..2078344 (-) 270 WP_003105467.1 hypothetical protein -
  SPB_RS10490 (SPB_2164) - 2078673..2078873 (+) 201 WP_003104168.1 cold-shock protein -
  SPB_RS10495 (SPB_2165) - 2079051..2079518 (+) 468 WP_003103836.1 CtsR family transcriptional regulator -
  SPB_RS10500 (SPB_2166) clpC 2079511..2081955 (+) 2445 WP_003102418.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  SPB_RS10505 (SPB_2167) groES 2082150..2082434 (+) 285 WP_003105909.1 co-chaperone GroES -
  SPB_RS10510 (SPB_2168) groL 2082472..2084100 (+) 1629 WP_003104684.1 chaperonin GroEL -
  SPB_RS11555 - 2084250..2084315 (+) 66 WP_142380692.1 YSIRK-type signal peptide-containing protein -
  SPB_RS11560 (SPB_2169) - 2084325..2085041 (+) 717 WP_003105434.1 hypothetical protein -
  SPB_RS11565 (SPB_2170) - 2085126..2085461 (+) 336 WP_003103479.1 hypothetical protein -

Sequence

Protein


Download         Length: 814 a.a.        Molecular weight: 90227.56 Da        Isoelectric Point: 6.0116

>NTDB_id=64577 SPB_RS10500 WP_003102418.1 2079511..2081955(+) (clpC) [Streptococcus parauberis NCFD 2020]
MIDYSIKMQEIFKQAQYQAARFGSSHLETWHILLAMVKEEGSLAGLVFSEFNNKISEEEYEAAAILAVGKSPQDDIKEVH
FLGQSKTLTNILKFSEMISLVTNASEVGSEHVLFAILLNPDIMAARLLEMAGFKIKDDGQGQPKLADLRKAIEIQAAYSK
ETIKAIHELRKPKKAKGAGSFSDMMKPASTAGDLSDFTRDLTEMANQGLLEPVIGRDKEITRMIQVLSRKTKNNPVLVGD
AGVGKTALAYGLAQRIANGSIPYELQDMRVLELDMMSVVAGTRFRGDFEERMNQIIDDIETDGQIILFVDELHTIMGSGS
GIDSTLDAANILKPALSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKVLIEEPNLEDAYQILLGLKGSYERFHNVSISD
QAVKTAVKVAHRYLTSKNLPDSAIDLLDEASATVQGLVKKEKASILTPIDQAILEKDFKTVSKLLKAQVNNKSAKPTLVT
EDNIMSTLSKLSGIPVEKLTQADSKKYLNLEKELHKRVIGQEDAVSAISRAIRRNQSGIRTGRRPIGSFMFLGPTGVGKT
ELAKALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQ
VLDDGMLTDSRGRRVDFSNTIIIMTSNLGATALRDDKTVGFGAKDISQDHQAMEKRILEELKKSYRPEFINRIDEKVVFH
SLSQEDMKEVVMIMVKPLVTNLAEKGVSLKIQPSALNYLSEEGYDVEMGARPLRRTIQTHIEDKLSELILSGDLSSGHQL
KIGMSHGKLKFDIE

Nucleotide


Download         Length: 2445 bp        

>NTDB_id=64577 SPB_RS10500 WP_003102418.1 2079511..2081955(+) (clpC) [Streptococcus parauberis NCFD 2020]
ATGATTGATTACTCAATAAAGATGCAAGAGATATTTAAACAGGCCCAGTACCAAGCAGCTCGCTTTGGCAGTTCGCATTT
GGAGACCTGGCATATTCTCTTAGCAATGGTGAAAGAAGAAGGTTCCCTAGCAGGATTAGTTTTTAGTGAATTTAATAATA
AAATTTCAGAAGAAGAATATGAAGCAGCTGCAATTTTGGCCGTGGGAAAAAGTCCTCAAGATGATATTAAAGAAGTACAT
TTCTTAGGTCAGTCCAAGACTTTAACCAATATTCTTAAGTTTTCTGAAATGATAAGTTTGGTTACAAATGCTTCTGAAGT
AGGTTCAGAGCATGTTCTTTTTGCAATTTTGTTAAATCCAGATATTATGGCTGCCCGACTCTTAGAGATGGCTGGCTTCA
AAATTAAGGATGATGGACAAGGACAACCAAAGCTTGCTGATCTCAGAAAAGCTATTGAAATACAGGCGGCATATAGTAAA
GAAACAATTAAAGCTATTCATGAGTTACGAAAACCTAAAAAAGCCAAAGGTGCTGGATCTTTTTCTGACATGATGAAGCC
GGCTAGTACAGCTGGAGACTTGTCAGATTTCACCAGAGACCTAACGGAAATGGCCAACCAAGGATTATTAGAACCAGTTA
TCGGCAGAGATAAAGAAATCACACGGATGATTCAGGTTCTCAGTCGTAAAACCAAGAACAATCCTGTACTAGTTGGAGAT
GCTGGTGTTGGTAAGACAGCCTTAGCTTATGGACTAGCTCAACGGATTGCCAATGGATCAATTCCTTATGAATTGCAAGA
TATGCGGGTCTTGGAATTAGATATGATGAGTGTTGTTGCGGGTACACGTTTCCGTGGGGACTTCGAAGAAAGAATGAATC
AAATCATCGACGATATTGAGACGGATGGTCAGATTATTCTTTTTGTTGATGAACTACATACAATCATGGGTTCTGGTAGT
GGGATTGACAGTACTTTAGATGCAGCAAATATTTTAAAACCTGCTTTATCACGTGGAACGCTCCATATGGTAGGTGCGAC
AACACAAGAAGAGTATCAAAAACATATTGAAAAAGATGCAGCTTTATCTCGTCGTTTTGCGAAAGTGCTTATCGAAGAAC
CAAATTTGGAAGATGCTTATCAAATTTTGTTAGGACTAAAAGGATCTTATGAACGTTTCCATAATGTTTCAATTTCAGAC
CAAGCGGTCAAGACGGCTGTTAAGGTAGCTCATCGCTATTTAACCAGTAAAAATCTTCCTGATTCAGCCATTGACTTATT
AGATGAAGCAAGTGCAACGGTTCAAGGGTTAGTCAAAAAAGAAAAAGCTTCCATCTTAACACCAATTGATCAAGCTATTC
TAGAGAAGGATTTCAAAACAGTTTCAAAACTATTGAAAGCTCAAGTTAATAACAAATCTGCAAAGCCTACACTAGTGACT
GAAGATAATATCATGTCTACACTAAGCAAGTTATCAGGAATTCCTGTTGAAAAACTAACCCAAGCAGATAGCAAAAAATA
TCTTAACTTGGAAAAAGAATTGCATAAGCGTGTGATTGGTCAAGAAGATGCTGTATCAGCAATATCACGGGCAATTCGTC
GCAATCAGTCAGGAATTAGAACAGGCAGACGACCTATTGGTTCATTCATGTTCTTAGGGCCAACGGGAGTTGGTAAAACA
GAATTAGCAAAAGCTTTAGCAGAAGTTCTCTTTGATGATGAGTCAGCACTAATTCGATTCGATATGTCCGAGTATATGGA
AAAATTTGCAGCTAGTCGATTAAATGGGGCACCTCCAGGCTATGTCGGCTATGAAGAAGGTGGCGAACTGACAGAAAAGG
TTAGAAATAAACCTTATTCTGTTCTACTATTTGATGAAGTTGAAAAAGCCCATCCGGATATCTTTAATGTCCTATTGCAA
GTTCTAGATGATGGGATGTTAACAGACAGTCGCGGGCGTCGCGTTGATTTCTCAAACACCATTATTATTATGACTAGTAA
CTTGGGCGCGACGGCCTTACGTGATGATAAAACAGTTGGTTTTGGTGCCAAAGATATTTCTCAAGACCACCAAGCCATGG
AAAAACGAATTTTGGAAGAATTGAAGAAATCCTACAGACCAGAATTCATTAACAGGATAGATGAGAAGGTAGTCTTCCAT
AGCCTCAGTCAAGAGGATATGAAAGAAGTAGTGATGATTATGGTTAAACCATTAGTTACTAATTTGGCGGAAAAAGGCGT
TAGTCTGAAAATTCAACCATCGGCCCTCAACTATCTCTCAGAGGAAGGCTATGATGTGGAGATGGGGGCAAGACCACTCC
GAAGAACGATACAAACGCATATTGAAGATAAACTGTCAGAATTGATTCTTTCTGGCGACTTATCTAGTGGACACCAGTTG
AAAATAGGAATGTCCCATGGCAAATTAAAATTTGACATAGAATAA

Domains

Predicted by InterproScan.

ATPase family associated with various cellular activities (AAA) (AAA)

(236-368)

AAA lid domain (AAA_lid_9)

(376-453)

AAA domain (Cdc48 subfamily) (AAA_2)

(544-715)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(18-51)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(105-136)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(722-801)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1S1ZRW2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Streptococcus mutans UA159

74.17

99.877

0.741
  clpC Streptococcus thermophilus LMD-9

71.516

100

0.719
  clpC Streptococcus thermophilus LMG 18311

71.516

100

0.719
  clpC Streptococcus pneumoniae Rx1

66.748

100

0.668
  clpC Streptococcus pneumoniae D39

66.748

100

0.668
  clpC Streptococcus pneumoniae TIGR4

66.626

100

0.667
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

48.019

100

0.491
  clpC Bacillus subtilis subsp. subtilis str. 168

45.042

100

0.463

Multiple sequence alignment