Detailed information NTG0645710

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: L1A14_RS09240
• Genome accession: NZ_CP090883
• Coordinates: 1784660..1785697 (-)
• Length: 345 a.a.
• NCBI ID: WP_000727279.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain LE4448
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1779660..1790697

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
L1A14_RS09215 (L1A14_09215)	-	1780399..1781730 (-)	1332	WP_000390039.1	hemolysin family protein	-
L1A14_RS09220 (L1A14_09220)	endA	1782021..1782845 (-)	825	WP_001036786.1	DNA-entry nuclease EndA	Machinery gene
L1A14_RS09225 (L1A14_09225)	-	1782884..1783072 (-)	189	WP_001036519.1	DNA-directed RNA polymerase subunit beta	-
L1A14_RS09230 (L1A14_09230)	murA	1783065..1784348 (-)	1284	WP_000358034.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
L1A14_RS09235 (L1A14_09235)	-	1784372..1784602 (-)	231	WP_001809307.1	DUF1146 family protein	-
L1A14_RS09240 (L1A14_09240)	sepM	1784660..1785697 (-)	1038	WP_000727279.1	SepM family pheromone-processing serine protease	Regulator
L1A14_RS09245 (L1A14_09245)	coaD	1785681..1786169 (-)	489	WP_001280736.1	pantetheine-phosphate adenylyltransferase	-
L1A14_RS09250 (L1A14_09250)	rsmD	1786159..1786698 (-)	540	WP_000706951.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
L1A14_RS09255 (L1A14_09255)	asnA	1786763..1787755 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
L1A14_RS09260 (L1A14_09260)	-	1787867..1788550 (-)	684	WP_001016917.1	Bax inhibitor-1/YccA family protein	-
L1A14_RS09265 (L1A14_09265)	-	1788606..1789346 (-)	741	WP_000152680.1	RNA methyltransferase	-
L1A14_RS09270 (L1A14_09270)	-	1789380..1789658 (+)	279	WP_001174613.1	acylphosphatase	-
L1A14_RS09275 (L1A14_09275)	yidC	1789736..1790662 (+)	927	WP_000835949.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37565.63 Da
• Isoelectric Point: 5.0724

>NTDB_id=645710 L1A14_RS09240 WP_000727279.1 1784660..1785697(-) (sepM) [Streptococcus pneumoniae strain LE4448]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHPDVKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=645710 L1A14_RS09240 WP_000727279.1 1784660..1785697(-) (sepM) [Streptococcus pneumoniae strain LE4448]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCACAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACGGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGACTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAGATTATCACCTTGGAAAATGGAAAAAATGGGATTGGAATCGGCTTGATTGATCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGCCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGTGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (231-298)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.357	99.13	0.588