Detailed information NTG0645699

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: L1A14_RS08780
• Genome accession: NZ_CP090883
• Coordinates: 1709110..1710177 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159555.1
• Uniprot ID: A0A0I8P776
• Organism: Streptococcus pneumoniae strain LE4448
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1704110..1715177

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
L1A14_RS08765 (L1A14_08765)	treR	1705898..1706608 (+)	711	WP_000760673.1	trehalose operon repressor	Regulator
L1A14_RS08770 (L1A14_08770)	-	1706763..1708098 (+)	1336	Protein_1742	ISL3 family transposase	-
L1A14_RS08775 (L1A14_08775)	amiF	1708173..1709099 (-)	927	WP_001291293.1	ATP-binding cassette domain-containing protein	Regulator
L1A14_RS08780 (L1A14_08780)	amiE	1709110..1710177 (-)	1068	WP_000159555.1	ABC transporter ATP-binding protein	Regulator
L1A14_RS08785 (L1A14_08785)	amiD	1710186..1711112 (-)	927	WP_000103700.1	oligopeptide ABC transporter permease OppC	Regulator
L1A14_RS08790 (L1A14_08790)	amiC	1711112..1712608 (-)	1497	WP_000759902.1	ABC transporter permease	Regulator
L1A14_RS08795 (L1A14_08795)	amiA3	1712675..1714654 (-)	1980	WP_000742234.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39489.14 Da
• Isoelectric Point: 5.0389

>NTDB_id=645699 L1A14_RS08780 WP_000159555.1 1709110..1710177(-) (amiE) [Streptococcus pneumoniae strain LE4448]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSKTHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=645699 L1A14_RS08780 WP_000159555.1 1709110..1710177(-) (amiE) [Streptococcus pneumoniae strain LE4448]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTCGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGTATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCTT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAAAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

• ABC transporter (ABC_tran) (29-187)

3D structure

• AlphaFold DB: A0A0I8P776

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	88.169	100	0.882
amiE	Streptococcus thermophilus LMG 18311	86.479	100	0.865
amiE	Streptococcus thermophilus LMD-9	86.479	100	0.865
oppD	Streptococcus mutans UA159	54.545	99.155	0.541