Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   L1A12_RS09065 Genome accession   NZ_CP090882
Coordinates   1778462..1779286 (-) Length   274 a.a.
NCBI ID   WP_001036787.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain CH2241     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1773462..1784286
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L1A12_RS09060 (L1A12_09060) - 1776840..1778171 (-) 1332 WP_000390039.1 hemolysin family protein -
  L1A12_RS09065 (L1A12_09065) endA 1778462..1779286 (-) 825 WP_001036787.1 DNA-entry nuclease EndA Machinery gene
  L1A12_RS09070 (L1A12_09070) - 1779325..1779513 (-) 189 WP_001813390.1 DNA-directed RNA polymerase subunit beta -
  L1A12_RS09075 (L1A12_09075) murA 1779506..1780789 (-) 1284 WP_000358028.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  L1A12_RS09080 (L1A12_09080) - 1780813..1781043 (-) 231 WP_000250384.1 DUF1146 family protein -
  L1A12_RS09085 (L1A12_09085) sepM 1781101..1782138 (-) 1038 WP_000727277.1 SepM family pheromone-processing serine protease Regulator
  L1A12_RS09090 (L1A12_09090) coaD 1782122..1782610 (-) 489 WP_001280769.1 pantetheine-phosphate adenylyltransferase -
  L1A12_RS09095 (L1A12_09095) rsmD 1782600..1783139 (-) 540 WP_000706963.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  L1A12_RS09100 (L1A12_09100) asnA 1783204..1784196 (-) 993 WP_000747993.1 aspartate--ammonia ligase -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29917.60 Da        Isoelectric Point: 10.1197

>NTDB_id=645624 L1A12_RS09065 WP_001036787.1 1778462..1779286(-) (endA) [Streptococcus pneumoniae strain CH2241]
MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTNLSQKKQGPEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide


Download         Length: 825 bp        

>NTDB_id=645624 L1A12_RS09065 WP_001036787.1 1778462..1779286(-) (endA) [Streptococcus pneumoniae strain CH2241]
ATGAACAAAAAAACAAGACAGACACTAATCGGACTGCTAGTGTTATTGCTTTTGTCTACAGGGAGCTATTATATCAAGCA
GATGCAGTCGGCACCTAATAGTCCCAAAACCAATCTTAGTCAGAAAAAACAAGGGCCTGAAGCTCCTAGTCAAGCATTGG
CAGAGAGTGTCTTAACAGACGCAGTCAAGAGTCAAATAAAGGGGAGTCTGGAGTGGAATGGCTCAGGTGCTTTTATCGTC
AATGGTAATAAAACAAATCTAGATGCCAAGGTTTCAAGTAAGCCCTACGCTGACAATAAAACAAAGACAGTGGGCAAGGA
AACTGTTCCAACCGTAGCTAATGCCCTCTTGTCTAAGGCCACTCGTCAGTACAAGAATCGTAAAGAAACTGGGAATGGTT
CAACTTCTTGGACTCCTCCAGGTTGGCATCAGGTCAAGAATCTAAAGGGCTCTTATACCCATGCAGTCGATAGAGGTCAT
TTGTTAGGCTATGCCTTAATCGGTGGTTTGGATGGTTTTGATGCCTCAACAAGCAATCCTAAAAACATTGCTGTTCAGAC
AGCCTGGGCAAATCAGGCACAAGCCGAGTATTCGACTGGTCAAAACTACTATGAAAGCAAGGTGCGTAAAGCCTTGGACC
AAAACAAGCGTGTCCGTTACCGTGTAACCCTTTACTACGCTTCAAACGAGGATTTAGTTCCCTCAGCTTCACAGATTGAA
GCCAAGTCTTCGGATGGAGAATTGGAATTCAATGTTCTAGTTCCCAATGTTCAAAAGGGACTTCAACTGGATTACCGAAC
TGGAGAAGTAACTGTAACTCAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(75-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

98.905

100

0.989
  endA Streptococcus pneumoniae D39

98.905

100

0.989
  endA Streptococcus pneumoniae R6

98.905

100

0.989
  endA Streptococcus pneumoniae TIGR4

98.905

100

0.989