Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   L1A11_RS00345 Genome accession   NZ_CP090881
Coordinates   55772..56596 (+) Length   274 a.a.
NCBI ID   WP_001036786.1    Uniprot ID   A0A0B7LDF1
Organism   Streptococcus pneumoniae strain BR1268     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 50772..61596
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L1A11_RS00310 (L1A11_00310) asnA 50862..51854 (+) 993 WP_000747993.1 aspartate--ammonia ligase -
  L1A11_RS00315 (L1A11_00315) rsmD 51919..52458 (+) 540 WP_000706951.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  L1A11_RS00320 (L1A11_00320) coaD 52448..52936 (+) 489 WP_001280736.1 pantetheine-phosphate adenylyltransferase -
  L1A11_RS00325 (L1A11_00325) sepM 52920..53957 (+) 1038 WP_000727279.1 SepM family pheromone-processing serine protease Regulator
  L1A11_RS00330 (L1A11_00330) - 54015..54245 (+) 231 WP_001809307.1 DUF1146 family protein -
  L1A11_RS00335 (L1A11_00335) murA 54269..55552 (+) 1284 WP_000358034.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  L1A11_RS00340 (L1A11_00340) - 55545..55733 (+) 189 WP_001036519.1 DNA-directed RNA polymerase subunit beta -
  L1A11_RS00345 (L1A11_00345) endA 55772..56596 (+) 825 WP_001036786.1 DNA-entry nuclease EndA Machinery gene
  L1A11_RS00350 (L1A11_00350) - 56887..58218 (+) 1332 WP_000390039.1 hemolysin family protein -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29921.59 Da        Isoelectric Point: 10.1197

>NTDB_id=645503 L1A11_RS00345 WP_001036786.1 55772..56596(+) (endA) [Streptococcus pneumoniae strain BR1268]
MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTNLSQKKQASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide


Download         Length: 825 bp        

>NTDB_id=645503 L1A11_RS00345 WP_001036786.1 55772..56596(+) (endA) [Streptococcus pneumoniae strain BR1268]
ATGAACAAAAAAACAAGACAGACACTAATCGGACTGCTAGTGTTATTGCTTTTGTCTACAGGGAGCTATTATATCAAGCA
GATGCAGTCGGCACCTAATAGTCCCAAAACCAATCTTAGTCAGAAAAAACAAGCGTCTGAAGCTCCTAGTCAAGCATTGG
CAGAGAGTGTCTTAACAGACGCAGTCAAGAGTCAAATAAAGGGGAGTCTGGAGTGGAATGGCTCAGGTGCTTTTATCGTC
AATGGTAATAAAACAAATCTAGATGCCAAGGTTTCAAGTAAGCCCTACGCTGACAATAAAACAAAGACAGTGGGCAAGGA
AACTGTTCCAACCGTAGCTAATGCCCTCTTGTCTAAGGCCACTCGTCAGTACAAGAATCGTAAAGAAACTGGGAATGGTT
CAACTTCTTGGACTCCTCCAGGTTGGCATCAGGTCAAGAATCTAAAGGGCTCTTATACCCATGCAGTCGATAGAGGTCAT
TTGTTAGGCTATGCCTTAATCGGTGGTTTGGATGGTTTTGATGCCTCAACAAGCAATCCTAAAAACATTGCTGTTCAGAC
AGCCTGGGCAAATCAGGCACAAGCCGAGTATTCGACTGGTCAAAACTACTATGAAAGCAAGGTGCGTAAAGCCTTGGACC
AAAACAAGCGTGTCCGTTACCGTGTAACCCTTTACTACGCTTCAAACGAGGATTTAGTTCCCTCAGCTTCACAGATTGAA
GCCAAGTCTTCGGATGGAGAATTGGAATTCAATGTTCTAGTTCCCAATGTTCAAAAGGGACTTCAACTGGATTACCGAAC
TGGAGAAGTAACTGTAACTCAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(75-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7LDF1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

99.635

100

0.996
  endA Streptococcus pneumoniae D39

99.635

100

0.996
  endA Streptococcus pneumoniae R6

99.635

100

0.996
  endA Streptococcus pneumoniae TIGR4

99.635

100

0.996