Detailed information NTG0645502

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: L1A11_RS00325
• Genome accession: NZ_CP090881
• Coordinates: 52920..53957 (+)
• Length: 345 a.a.
• NCBI ID: WP_000727279.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain BR1268
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 47920..58957

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
L1A11_RS00290 (L1A11_00290)	yidC	47955..48881 (-)	927	WP_000835949.1	membrane protein insertase YidC	-
L1A11_RS00295 (L1A11_00295)	-	48959..49237 (-)	279	WP_001174613.1	acylphosphatase	-
L1A11_RS00300 (L1A11_00300)	-	49271..50011 (+)	741	WP_000152680.1	RNA methyltransferase	-
L1A11_RS00305 (L1A11_00305)	-	50067..50750 (+)	684	WP_001016917.1	Bax inhibitor-1/YccA family protein	-
L1A11_RS00310 (L1A11_00310)	asnA	50862..51854 (+)	993	WP_000747993.1	aspartate--ammonia ligase	-
L1A11_RS00315 (L1A11_00315)	rsmD	51919..52458 (+)	540	WP_000706951.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
L1A11_RS00320 (L1A11_00320)	coaD	52448..52936 (+)	489	WP_001280736.1	pantetheine-phosphate adenylyltransferase	-
L1A11_RS00325 (L1A11_00325)	sepM	52920..53957 (+)	1038	WP_000727279.1	SepM family pheromone-processing serine protease	Regulator
L1A11_RS00330 (L1A11_00330)	-	54015..54245 (+)	231	WP_001809307.1	DUF1146 family protein	-
L1A11_RS00335 (L1A11_00335)	murA	54269..55552 (+)	1284	WP_000358034.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
L1A11_RS00340 (L1A11_00340)	-	55545..55733 (+)	189	WP_001036519.1	DNA-directed RNA polymerase subunit beta	-
L1A11_RS00345 (L1A11_00345)	endA	55772..56596 (+)	825	WP_001036786.1	DNA-entry nuclease EndA	Machinery gene
L1A11_RS00350 (L1A11_00350)	-	56887..58218 (+)	1332	WP_000390039.1	hemolysin family protein	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37565.63 Da
• Isoelectric Point: 5.0724

>NTDB_id=645502 L1A11_RS00325 WP_000727279.1 52920..53957(+) (sepM) [Streptococcus pneumoniae strain BR1268]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHPDVKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=645502 L1A11_RS00325 WP_000727279.1 52920..53957(+) (sepM) [Streptococcus pneumoniae strain BR1268]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCACAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACGGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGACTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAGATTATCACCTTGGAAAATGGAAAAAATGGGATTGGAATCGGCTTGATTGATCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGCCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGTGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (231-298)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.357	99.13	0.588