Detailed information NTG0645491

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: OG888_RS21515
• Genome accession: NZ_CP107749
• Coordinates: 4761701..4762825 (+)
• Length: 374 a.a.
• NCBI ID: WP_266711290.1
• Uniprot ID: -
• Organism: Streptomyces sp. NBC_00622
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 4756701..4767825

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OG888_RS21500 (OG888_21525)	-	4757327..4758208 (+)	882	WP_327662853.1	hypothetical protein	-
OG888_RS21505 (OG888_21530)	-	4758239..4759951 (-)	1713	WP_327670762.1	BACON domain-containing protein	-
OG888_RS21510 (OG888_21535)	radA/sms	4760202..4761608 (+)	1407	WP_266711289.1	DNA repair protein RadA	Machinery gene
OG888_RS21515 (OG888_21540)	disA	4761701..4762825 (+)	1125	WP_266711290.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
OG888_RS21520 (OG888_21545)	-	4762902..4763735 (-)	834	WP_327670763.1	hypothetical protein	-
OG888_RS21525 (OG888_21550)	-	4763922..4764587 (+)	666	WP_327662850.1	phosphatase PAP2 family protein	-
OG888_RS21530 (OG888_21555)	-	4764666..4765349 (-)	684	WP_327662849.1	response regulator transcription factor	-
OG888_RS21535 (OG888_21560)	-	4765337..4766929 (-)	1593	WP_327670764.1	histidine kinase	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40051.83 Da
• Isoelectric Point: 4.9989

>NTDB_id=645491 OG888_RS21515 WP_266711290.1 4761701..4762825(+) (disA) [Streptomyces sp. NBC_00622]
MAANDRAATPGKSGGSSGADSLMRAALSAVAPGTALRDGLERILRGNTGGLIVLGSDKTVESMCTGGFILDVEFTATRLR
ELCKLDGGIVVSSNLDKILRAGVQLVPDPTIPTEETGTRHRTADRVSKQVGYTVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIA
GVEPERELVARDYVPEPTAKRSRTVPEALVELDALSHAELLELPIVARALGYTGSPEALDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=645491 OG888_RS21515 WP_266711290.1 4761701..4762825(+) (disA) [Streptomyces sp. NBC_00622]
GTGGCAGCCAATGACCGGGCGGCAACTCCCGGCAAGTCCGGCGGAAGCTCCGGTGCGGACAGTCTGATGCGCGCCGCGCT
GAGTGCCGTCGCGCCCGGAACCGCCCTGCGCGACGGCCTGGAGCGCATCCTCCGCGGCAACACCGGAGGACTCATCGTCC
TCGGCTCCGACAAGACGGTCGAGTCGATGTGCACGGGCGGCTTCATCCTCGACGTGGAGTTCACGGCCACGCGCCTGCGC
GAGCTGTGCAAACTCGACGGCGGCATCGTGGTCTCCTCGAACCTCGACAAGATCCTGCGGGCCGGCGTCCAGTTGGTGCC
GGACCCCACGATCCCCACCGAGGAGACCGGCACCCGGCACCGCACGGCGGACCGGGTCTCCAAGCAGGTCGGCTACACCG
TCGTCTCGGTCTCCCAGTCGATGCGCCTGATCGCGCTGTACGTGGACGGGCAGCGCCGCGTCCTGGAGGACTCGGCGGCG
ATCCTGTCCCGGGCCAACCAGGCCCTCGCGACCCTGGAGCGCTACAAGCTGCGCCTCGACGAGGTGGCGGGCACGCTCTC
CGCCCTGGAGATCGAGGACCTGGTCACGGTCCGGGACGTCTCGGCGGTCGCGCAGCGCCTGGAGATGGTGCGGCGCATCG
CCACGGAGATCGCCGAGTACGTCGTCGAGTTGGGCACGGACGGCCGGCTTCTGGCGCTGCAGCTCGACGAGTTGATCGCG
GGCGTCGAGCCGGAGCGCGAACTGGTCGCGCGGGACTACGTGCCCGAGCCCACCGCCAAGCGTTCCCGCACGGTCCCGGA
GGCGCTGGTCGAGCTGGACGCGCTCAGCCACGCGGAACTGCTCGAACTGCCGATAGTGGCACGGGCACTGGGCTACACCG
GCTCCCCCGAGGCACTCGACTCGGCGGTGTCCCCGCGCGGCTTCCGTCTCCTGGCCAAGGTGCCGCGCCTCCCTGGCGCC
ATCATCGACCGCCTCGTGGAGCACTTCGGCGGCCTGCAGAAGTTGCTGGCCGCGAGCGTGGACGACCTTCAGACGGTCGA
CGGGGTCGGAGAGGCGCGGGCGCGGAGCGTCCGGGAGGGCCTGTCGCGGTTGGCGGAGTCGTCGATCCTCGAGCGGTACG
TATAG

Domains

Predicted by InterProScan.

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	45.856	96.791	0.444