Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   L1A04_RS09185 Genome accession   NZ_CP090879
Coordinates   1871148..1871864 (-) Length   238 a.a.
NCBI ID   WP_234877943.1    Uniprot ID   -
Organism   Staphylococcus aureus strain SAUR_BFS2     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1866148..1876864
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L1A04_RS09170 (L1A04_09170) - 1867235..1868185 (+) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -
  L1A04_RS09175 (L1A04_09175) - 1868334..1869818 (+) 1485 WP_001791588.1 sucrose-6-phosphate hydrolase -
  L1A04_RS09180 (L1A04_09180) - 1869815..1870774 (+) 960 WP_234877942.1 carbohydrate kinase family protein -
  L1A04_RS09185 (L1A04_09185) agrA 1871148..1871864 (-) 717 WP_234877943.1 quorum-sensing response regulator AgrA Regulator
  L1A04_RS09190 (L1A04_09190) agrC 1871883..1873175 (-) 1293 WP_000387809.1 quorum-sensing sensor histidine kinase AgrC -
  L1A04_RS09195 (L1A04_09195) agrD 1873200..1873340 (-) 141 WP_000735197.1 cyclic lactone autoinducer peptide AgrD -
  L1A04_RS09200 (L1A04_09200) - 1873344..1873907 (-) 564 WP_001105709.1 accessory gene regulator AgrB -
  L1A04_RS09205 (L1A04_09205) hld 1874197..1874277 (+) 81 WP_000046022.1 delta-hemolysin -
  L1A04_RS09210 (L1A04_09210) - 1874880..1875665 (-) 786 WP_000867948.1 carbon-nitrogen family hydrolase -
  L1A04_RS09215 (L1A04_09215) - 1876026..1876652 (-) 627 WP_000522388.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27954.97 Da        Isoelectric Point: 6.0926

>NTDB_id=645476 L1A04_RS09185 WP_234877943.1 1871148..1871864(-) (agrA) [Staphylococcus aureus strain SAUR_BFS2]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDIYGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=645476 L1A04_RS09185 WP_234877943.1 1871148..1871864(-) (agrA) [Staphylococcus aureus strain SAUR_BFS2]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATCAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTTATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAAAGATAATAGCGTTGAAACGATTGAGTTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTCAGATGTCATAATAGCTTTGTCGTCAATCGTCATAATATCGAATCTATTG
ATTCGAAAGAGCGTATTGTTTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996