Detailed information NTG0064543

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: SPB_RS04945
• Genome accession: NZ_AEUT02000001
• Coordinates: 987934..988971 (-)
• Length: 345 a.a.
• NCBI ID: WP_003106043.1
• Uniprot ID: A0A0E2UF26
• Organism: Streptococcus parauberis NCFD 2020
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 982934..993971

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPB_RS04920 (SPB_1016)	rbsC	982984..983934 (-)	951	WP_003105746.1	ribose ABC transporter permease	-
SPB_RS04925 (SPB_1017)	-	983936..985414 (-)	1479	WP_003102471.1	sugar ABC transporter ATP-binding protein	-
SPB_RS04930 (SPB_1018)	rbsD	985426..985824 (-)	399	WP_003102489.1	D-ribose pyranase	-
SPB_RS04935 (SPB_1019)	rbsK	985799..986710 (-)	912	WP_003103508.1	ribokinase	-
SPB_RS04940 (SPB_1020)	-	986712..987686 (-)	975	WP_003105284.1	LacI family DNA-binding transcriptional regulator	-
SPB_RS04945 (SPB_1021)	sepM	987934..988971 (-)	1038	WP_003106043.1	SepM family pheromone-processing serine protease	Regulator
SPB_RS04950 (SPB_1022)	coaD	988958..989449 (-)	492	WP_003103109.1	pantetheine-phosphate adenylyltransferase	-
SPB_RS04955 (SPB_1023)	rsmD	989439..989978 (-)	540	WP_037621167.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
SPB_RS04960 (SPB_1024)	asnA	990065..991057 (-)	993	WP_003105278.1	aspartate--ammonia ligase	-
SPB_RS04965 (SPB_1025)	arcC	991225..992175 (-)	951	WP_003103897.1	carbamate kinase	-
SPB_RS04970 (SPB_1026)	-	992199..993530 (-)	1332	WP_003105780.1	dipeptidase	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37520.30 Da
• Isoelectric Point: 9.9732

>NTDB_id=64543 SPB_RS04945 WP_003106043.1 987934..988971(-) (sepM) [Streptococcus parauberis NCFD 2020]
MKKNNKLKIWLLGIIAVIAIGFSLFYPLPYYIEMPGGAYDIRSVLKVNEQKDKEKGSYNFVAVSISHATFAQILYAWATP
FTEISSAEATTGGYSDADYMRINQFYMETSQNGAVYQALKKAGKPVSLDYLGVYVLDVSKNSSLKGVLNIADTVTSVNQK
HFKSSADLIKFVSAMKLGDKVSVQYTSNGKDKSANGKIIKLKNGKNGIGISLTDHTKVHTKEKIDFTTEGVGGPSAGLMF
TLDILDQINKEDLRKGRNIAGTGTIDQEGKVGDIGGAGLKVVAAAKEGAEIFFVPNNPVDPRVKKVDPKAITNYKEALEA
AKQLKTKMKIVPVKTVDDAISYLKK

Nucleotide

• Length: 1038 bp

>NTDB_id=64543 SPB_RS04945 WP_003106043.1 987934..988971(-) (sepM) [Streptococcus parauberis NCFD 2020]
ATGAAGAAAAATAATAAATTAAAAATTTGGTTATTGGGCATTATTGCTGTCATTGCAATTGGCTTTTCACTATTTTATCC
TCTACCTTATTATATTGAAATGCCTGGTGGTGCCTATGATATCCGTAGTGTCCTTAAGGTAAATGAACAAAAAGACAAGG
AAAAAGGGTCTTATAATTTTGTTGCTGTAAGTATTAGTCATGCGACATTTGCACAAATTCTCTATGCTTGGGCAACACCA
TTTACAGAGATTTCATCAGCAGAAGCAACTACTGGTGGCTATAGTGATGCAGACTACATGAGAATTAATCAATTCTATAT
GGAAACTTCACAAAATGGTGCTGTTTATCAAGCTCTCAAAAAAGCTGGTAAACCTGTTTCCCTTGACTACTTAGGTGTTT
ATGTTCTTGATGTCAGTAAGAATTCTTCTCTTAAAGGGGTTTTGAATATTGCTGATACAGTTACAAGTGTTAATCAAAAA
CACTTTAAGAGTTCAGCTGATTTGATTAAGTTTGTGTCTGCCATGAAGTTGGGGGATAAAGTCAGTGTTCAATATACCAG
TAATGGTAAAGATAAATCAGCCAATGGTAAAATTATTAAGTTGAAAAATGGTAAAAATGGGATTGGAATCAGCTTAACTG
ACCATACCAAAGTACACACTAAAGAAAAAATTGATTTTACAACTGAAGGCGTTGGTGGTCCAAGTGCTGGTTTGATGTTC
ACCCTTGATATTCTTGACCAAATCAATAAAGAAGATTTACGTAAGGGGCGTAATATTGCTGGTACTGGTACAATTGACCA
AGAAGGTAAAGTTGGTGATATTGGTGGTGCAGGCTTAAAAGTAGTTGCGGCTGCTAAAGAAGGGGCAGAGATTTTCTTCG
TTCCTAATAATCCAGTTGATCCGCGTGTCAAAAAAGTTGATCCAAAAGCAATAACTAATTATAAAGAAGCCTTAGAAGCT
GCTAAGCAATTAAAAACAAAAATGAAGATTGTTCCAGTCAAGACAGTCGATGACGCAATCAGTTATCTGAAAAAGTAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-339)

• PDZ domain (PDZ_2) (131-195)

3D structure

• AlphaFold DB: A0A0E2UF26

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	68.986	100	0.69