Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   L0998_RS00935 Genome accession   NZ_CP090876
Coordinates   199170..199886 (-) Length   238 a.a.
NCBI ID   WP_054189591.1    Uniprot ID   -
Organism   Staphylococcus aureus strain SAUR_BFS12     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 194170..204886
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L0998_RS00915 (L0998_00915) - 195254..196204 (+) 951 WP_054189588.1 LacI family DNA-binding transcriptional regulator -
  L0998_RS00920 (L0998_00920) - 196353..197837 (+) 1485 WP_054189589.1 sucrose-6-phosphate hydrolase -
  L0998_RS00925 (L0998_00925) - 197834..198793 (+) 960 WP_054189590.1 carbohydrate kinase family protein -
  L0998_RS00930 (L0998_00930) - 198990..199098 (-) 109 Protein_172 hypothetical protein -
  L0998_RS00935 (L0998_00935) agrA 199170..199886 (-) 717 WP_054189591.1 quorum-sensing response regulator AgrA Regulator
  L0998_RS00940 (L0998_00940) agrC 199905..201197 (-) 1293 WP_054189592.1 quorum-sensing sensor histidine kinase AgrC -
  L0998_RS00945 (L0998_00945) agrD 201222..201362 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  L0998_RS00950 (L0998_00950) - 201359..201928 (-) 570 WP_054189593.1 accessory gene regulator AgrB -
  L0998_RS13485 (L0998_00955) hld 202218..202298 (+) 81 WP_000046022.1 delta-hemolysin -
  L0998_RS00960 (L0998_00960) - 202894..203679 (-) 786 WP_054189594.1 carbon-nitrogen family hydrolase -
  L0998_RS00965 (L0998_00965) - 204000..204626 (-) 627 WP_054189595.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27904.92 Da        Isoelectric Point: 6.3001

>NTDB_id=645375 L0998_RS00935 WP_054189591.1 199170..199886(-) (agrA) [Staphylococcus aureus strain SAUR_BFS12]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDNRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=645375 L0998_RS00935 WP_054189591.1 199170..199886(-) (agrA) [Staphylococcus aureus strain SAUR_BFS12]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACCGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGATCCA
GTTGGTAACATTATATTTGTTACGAGTCACAGTGAACTTACCTATTTAACTTTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCCGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACTAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATAATCGCTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996