Detailed information NTG0645344

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: L1A02_RS08210
• Genome accession: NZ_CP090873
• Coordinates: 1650626..1651669 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain SAUR_BFS16
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1645626..1656669

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
L1A02_RS08180 (L1A02_08180)	-	1646052..1646162 (+)	111	WP_001790257.1	hypothetical protein	-
L1A02_RS08185 (L1A02_08185)	-	1646191..1646604 (+)	414	WP_001557448.1	hypothetical protein	-
L1A02_RS08190 (L1A02_08190)	-	1647035..1648021 (-)	987	WP_000999717.1	FUSC family protein	-
L1A02_RS08195 (L1A02_08195)	map	1648552..1649310 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
L1A02_RS08200 (L1A02_08200)	-	1649527..1649913 (+)	387	WP_001110179.1	hypothetical protein	-
L1A02_RS08205 (L1A02_08205)	liaF	1649928..1650629 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
L1A02_RS08210 (L1A02_08210)	vraS	1650626..1651669 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
L1A02_RS08215 (L1A02_08215)	vraR	1651659..1652288 (+)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
L1A02_RS08220 (L1A02_08220)	-	1652401..1653618 (-)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
L1A02_RS08225 (L1A02_08225)	-	1653896..1654171 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
L1A02_RS08230 (L1A02_08230)	-	1654178..1654642 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
L1A02_RS08235 (L1A02_08235)	-	1654789..1654989 (+)	201	WP_000180460.1	DUF1128 family protein	-
L1A02_RS08240 (L1A02_08240)	-	1654992..1656248 (+)	1257	WP_001795108.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=645344 L1A02_RS08210 WP_001017131.1 1650626..1651669(+) (vraS) [Staphylococcus aureus strain SAUR_BFS16]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=645344 L1A02_RS08210 WP_001017131.1 1650626..1651669(+) (vraS) [Staphylococcus aureus strain SAUR_BFS16]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1