Detailed information NTG0645303

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: L0999_RS02100
• Genome accession: NZ_CP090870
• Coordinates: 391063..392106 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain SAUR_BFS62
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 386063..397106

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
L0999_RS02070 (L0999_02070)	-	386484..387740 (-)	1257	WP_001795108.1	aminopeptidase	-
L0999_RS02075 (L0999_02075)	-	387743..387943 (-)	201	WP_000180460.1	DUF1128 family protein	-
L0999_RS02080 (L0999_02080)	-	388090..388554 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
L0999_RS02085 (L0999_02085)	-	388561..388836 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
L0999_RS02090 (L0999_02090)	-	389114..390331 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
L0999_RS02095 (L0999_02095)	vraR	390444..391073 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
L0999_RS02100 (L0999_02100)	vraS	391063..392106 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
L0999_RS02105 (L0999_02105)	liaF	392103..392804 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
L0999_RS02110 (L0999_02110)	-	392819..393205 (-)	387	WP_001110179.1	hypothetical protein	-
L0999_RS02115 (L0999_02115)	map	393422..394180 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
L0999_RS02120 (L0999_02120)	-	394711..395697 (+)	987	WP_000999717.1	FUSC family protein	-
L0999_RS02125 (L0999_02125)	-	396128..396541 (-)	414	WP_001557448.1	hypothetical protein	-
L0999_RS02130 (L0999_02130)	-	396570..396680 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=645303 L0999_RS02100 WP_001017131.1 391063..392106(-) (vraS) [Staphylococcus aureus strain SAUR_BFS62]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=645303 L0999_RS02100 WP_001017131.1 391063..392106(-) (vraS) [Staphylococcus aureus strain SAUR_BFS62]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1