Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   LT978_RS13540 Genome accession   NZ_CP090838
Coordinates   2794177..2794833 (-) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus amyloliquefaciens strain TL106     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 2789177..2799833
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LT978_RS13520 (LT978_13515) spxH 2789416..2790318 (+) 903 WP_024085126.1 protease adaptor protein SpxH -
  LT978_RS13525 (LT978_13520) - 2790604..2790771 (+) 168 WP_003155026.1 hypothetical protein -
  LT978_RS13530 (LT978_13525) pepF 2790809..2792638 (-) 1830 WP_024085125.1 oligoendopeptidase F Regulator
  LT978_RS13535 (LT978_13530) - 2792866..2794026 (-) 1161 WP_044053100.1 competence protein CoiA family protein -
  LT978_RS13540 (LT978_13535) mecA 2794177..2794833 (-) 657 WP_003155032.1 adaptor protein MecA Regulator
  LT978_RS13550 (LT978_13545) - 2795109..2795765 (+) 657 WP_057080091.1 TerC family protein -
  LT978_RS13555 (LT978_13550) spx 2795823..2796218 (-) 396 WP_003155034.1 transcriptional regulator Spx -
  LT978_RS13560 (LT978_13555) - 2796397..2796975 (-) 579 WP_003155035.1 GNAT family N-acetyltransferase -
  LT978_RS13565 (LT978_13560) - 2797093..2798280 (-) 1188 WP_058905933.1 putative glycoside hydrolase -
  LT978_RS13570 (LT978_13565) oppF 2798387..2799304 (-) 918 WP_003155037.1 oligopeptide ABC transporter ATP-binding protein OppF -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=645082 LT978_RS13540 WP_003155032.1 2794177..2794833(-) (mecA) [Bacillus amyloliquefaciens strain TL106]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=645082 LT978_RS13540 WP_003155032.1 2794177..2794833(-) (mecA) [Bacillus amyloliquefaciens strain TL106]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCTGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCTTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGAAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895