Detailed information    

insolico Bioinformatically predicted

Overview

Name   sxy/tfoX   Type   Regulator
Locus tag   L0U94_RS20040 Genome accession   NZ_CP090834
Coordinates   4018205..4018801 (-) Length   198 a.a.
NCBI ID   WP_004150836.1    Uniprot ID   A0A0H3GL50
Organism   Klebsiella pneumoniae strain K-28     
Function   positive regulator of competence gene (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 4013413..4033680 4018205..4018801 within 0


Gene organization within MGE regions


Location: 4013413..4033680
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L0U94_RS20025 (L0U94_20000) helD 4013413..4015467 (-) 2055 WP_002898429.1 DNA helicase IV -
  L0U94_RS20030 (L0U94_20005) - 4015592..4016038 (+) 447 WP_002898425.1 YccF domain-containing protein -
  L0U94_RS20035 (L0U94_20010) yccS 4016056..4018191 (+) 2136 WP_002898422.1 YccS family putative transporter -
  L0U94_RS20040 (L0U94_20015) sxy/tfoX 4018205..4018801 (-) 597 WP_004150836.1 TfoX/Sxy family DNA transformation protein Regulator
  L0U94_RS20045 (L0U94_20020) sulA 4019150..4019659 (+) 510 WP_002898418.1 SOS-induced cell division inhibitor SulA -
  L0U94_RS20050 (L0U94_20025) ompA 4020012..4021082 (+) 1071 WP_062954987.1 porin OmpA -
  L0U94_RS20055 (L0U94_20030) matP 4021214..4021666 (-) 453 WP_002898404.1 macrodomain Ter protein MatP -
  L0U94_RS20060 (L0U94_20035) - 4021852..4023609 (+) 1758 WP_002898401.1 Lon protease family protein -
  L0U94_RS20065 (L0U94_20040) fabA 4023679..4024197 (+) 519 WP_002898398.1 bifunctional 3-hydroxydecanoyl-ACP dehydratase/trans-2-decenoyl-ACP isomerase -
  L0U94_RS20070 (L0U94_20045) rmf 4024266..4024433 (-) 168 WP_002898396.1 ribosome modulation factor -
  L0U94_RS20075 (L0U94_20050) pqiC 4024687..4025250 (-) 564 WP_002898392.1 membrane integrity-associated transporter subunit PqiC -
  L0U94_RS20080 (L0U94_20055) pqiB 4025250..4026888 (-) 1639 Protein_3951 intermembrane transport protein PqiB -
  L0U94_RS20085 (L0U94_20060) pqiA 4026878..4028146 (-) 1269 WP_002898387.1 membrane integrity-associated transporter subunit PqiA -
  L0U94_RS20090 (L0U94_20065) - 4028161..4030068 (-) 1908 WP_004150837.1 ABC transporter ATP-binding protein -
  L0U94_RS20095 (L0U94_20070) rlmKL 4030081..4032186 (-) 2106 WP_004147847.1 bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL -
  L0U94_RS20100 (L0U94_20075) - 4032286..4032435 (+) 150 Protein_3955 MOSC N-terminal beta barrel domain-containing protein -
  L0U94_RS20105 (L0U94_20080) - 4032490..4033680 (+) 1191 WP_256613096.1 IS3-like element ISKpn18 family transposase -

Sequence

Protein


Download         Length: 198 a.a.        Molecular weight: 22576.15 Da        Isoelectric Point: 10.1298

>NTDB_id=645009 L0U94_RS20040 WP_004150836.1 4018205..4018801(-) (sxy/tfoX) [Klebsiella pneumoniae strain K-28]
MRKLVCPRLPQFQACVSPLGQLHTRPLFGGYSLAIDDTVFAMVAEGNIYLKACEQSAAYRVEHRNPLLTLRRHGRIVPLK
YYQIDDTLWRDEQQLFRLSLLSWQSAQREKNYRRASGRLKDLPNISFHMELQLIHAGIPDVRTLREVGAQEAWLRLRVNN
ASLSLSVLLALEGAIAGVHAAALPTPRRQELLEWAATR

Nucleotide


Download         Length: 597 bp        

>NTDB_id=645009 L0U94_RS20040 WP_004150836.1 4018205..4018801(-) (sxy/tfoX) [Klebsiella pneumoniae strain K-28]
ATGAGAAAACTAGTTTGTCCGCGGCTCCCGCAATTTCAGGCCTGCGTCTCACCGCTGGGTCAACTGCATACTCGTCCGCT
CTTTGGCGGCTACAGCCTGGCTATTGATGATACGGTGTTTGCGATGGTGGCCGAGGGGAACATTTATCTGAAGGCCTGCG
AGCAGAGCGCTGCTTATCGGGTGGAACATCGTAATCCTCTGTTAACGCTGCGCCGACACGGCCGCATAGTGCCGCTGAAG
TATTATCAAATTGACGACACTTTATGGCGCGATGAGCAGCAGCTTTTTCGGCTATCGCTACTGTCGTGGCAGAGTGCGCA
GCGCGAAAAGAACTACCGACGGGCGTCGGGCCGCCTGAAGGATTTACCCAATATCAGCTTTCATATGGAATTGCAGCTGA
TTCACGCGGGCATACCGGACGTTAGGACGTTGCGGGAAGTTGGTGCGCAGGAGGCATGGCTGAGGCTACGCGTAAATAAT
GCTTCTTTATCGCTGAGCGTATTGCTGGCGCTGGAGGGGGCGATTGCCGGGGTACATGCCGCCGCGCTCCCGACGCCACG
GCGTCAGGAGCTTCTCGAATGGGCGGCTACCCGGTAG

Domains

Predicted by InterproScan.

TfoX C-terminal domain (TfoX_C)

(117-194)

TfoX N-terminal domain (TfoX_N)

(16-105)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H3GL50

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sxy/tfoX Escherichia coli BW25113 strain K-12

51.269

99.495

0.51