Detailed information NTG0644986

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: LL229_RS12440
• Genome accession: NZ_CP090823
• Coordinates: 2385694..2386722 (-)
• Length: 342 a.a.
• NCBI ID: WP_010906347.1
• Uniprot ID: A0AAP4JQE3
• Organism: Lactococcus lactis subsp. lactis strain 229
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 2380694..2391722

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LL229_RS12415 (LL229_2369)	-	2380980..2381477 (-)	498	WP_021214977.1	nitroreductase family protein	-
LL229_RS12420 (LL229_2370)	-	2381464..2381673 (-)	210	WP_003132661.1	hypothetical protein	-
LL229_RS12425 (LL229_2371)	-	2381670..2382497 (-)	828	WP_081172259.1	radical SAM protein	-
LL229_RS12430 (LL229_2372)	-	2382490..2384613 (-)	2124	WP_010906345.1	radical SAM protein	-
LL229_RS12435 (LL229_2373)	-	2384716..2385573 (-)	858	WP_010906346.1	transcriptional regulator	-
LL229_RS12440 (LL229_2374)	sepM	2385694..2386722 (-)	1029	WP_010906347.1	SepM family pheromone-processing serine protease	Regulator
LL229_RS12445 (LL229_2375)	coaD	2386709..2387206 (-)	498	WP_010906348.1	pantetheine-phosphate adenylyltransferase	-
LL229_RS12450 (LL229_2376)	rsmD	2387254..2387793 (-)	540	WP_015427191.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
LL229_RS12455 (LL229_2377)	-	2387964..2389184 (-)	1221	WP_003132654.1	MFS transporter	-
LL229_RS12460 (LL229_2378)	lmrP	2389268..2390494 (-)	1227	WP_021214981.1	multidrug efflux MFS transporter LmrP	-
LL229_RS12465 (LL229_2379)	-	2390682..2391176 (+)	495	WP_010906351.1	RNA polymerase sigma factor	-

Sequence

Protein

• Length: 342 a.a.
• Molecular weight: 37379.98 Da
• Isoelectric Point: 9.9183

>NTDB_id=644986 LL229_RS12440 WP_010906347.1 2385694..2386722(-) (sepM) [Lactococcus lactis subsp. lactis strain 229]
MKKNKKINPKLKWGISIGLIVVALLALFYPTSYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYSH
FNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAIYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELADTITAV
NGQQFTSSADMIAYVSKQKVGDSVTIEYTRIDGTKHKSTGKYIKIANGKTGIGISLVDHTEVVTTPKVTVNAGSIGGPSA
GMMFTLEIYSQLTGKDLRNGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKTAAKK
LKTKMKIVPVKTIQDALDYLEK

Nucleotide

• Length: 1029 bp

>NTDB_id=644986 LL229_RS12440 WP_010906347.1 2385694..2386722(-) (sepM) [Lactococcus lactis subsp. lactis strain 229]
ATGAAAAAAAATAAAAAAATTAATCCCAAATTAAAATGGGGAATCTCGATTGGTCTAATTGTTGTTGCCCTTTTAGCTTT
ATTTTATCCAACGAGTTACTATGTGGAAATGCCCGGAACAACCGAGCCTTTAGGGAAAATGGTCAAAGTTGAAGGCAAAA
AAGATGAACATAAAGGTGATTTTTTCCTGACGACTGTCCAAATTGCACGAGCAAATCTTGCTACAATGATTTACAGCCAT
TTTAATAGTTTTACAAGCATTTACAGTGAGCAAGAAATGACTGGTGGACTTAACGACGCACAGTTCAACCGTGTCAACCA
GTTTTACATGGAAACGGCACAGAATACAGCGATTTATCAAGCTTTTAAATTAGCTAATAAACCTTATGAACTTAAATATG
AAGGCGTTTATGTCCTTGATATTGCCAAAAATTCGACCTTTAAAAATAAGCTAGAACTTGCAGATACGATTACAGCAGTC
AATGGTCAACAGTTTACATCAAGTGCCGACATGATTGCTTATGTTTCCAAACAAAAAGTCGGTGATTCAGTAACGATTGA
ATACACGAGAATTGACGGCACAAAGCACAAGTCAACTGGCAAATACATCAAAATTGCTAATGGAAAAACAGGAATTGGGA
TCAGCCTAGTTGACCATACTGAAGTCGTGACGACTCCAAAAGTTACTGTCAACGCGGGTTCAATCGGTGGTCCCTCTGCG
GGGATGATGTTTACACTAGAAATTTACAGTCAGTTGACAGGAAAAGATTTGCGAAACGGTCGCGAAATTGCTGGAACTGG
AACGATTGAACATGACGGAAGCATTGGCCAAATCGGCGGTGTTGATAAAAAAGTAGCCACAGCGAGCAAAGAAGGGGCAA
AGGTCTTCTTAGTGCCTGACTCAGGCACCAAAAAGGAAAGCAGCAACAATTACCTTGGAGCCAAAACCGCAGCTAAAAAA
CTAAAAACGAAGATGAAAATCGTTCCCGTCAAAACTATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (134-194)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (227-338)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	48.696	100	0.491