Detailed information NTG0643466

Bioinformatically predicted

Overview

• Name: cytR
• Type: Regulator
• Locus tag: OF379_RS22850
• Genome accession: NZ_CP107284
• Coordinates: 4751399..4752424 (+)
• Length: 341 a.a.
• NCBI ID: WP_000644904.1
• Uniprot ID: P0ACN8
• Organism: Escherichia coli strain SW4848
• Function: promote competence gene expression (predicted from homology) Competence regulation

Genomic Context

Location: 4746399..4757424

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OF379_RS22830 (OF379_22830)	metJ	4747584..4747901 (+)	318	WP_000852812.1	met regulon transcriptional regulator MetJ	-
OF379_RS22835 (OF379_22835)	yiiX	4747961..4748569 (+)	609	WP_000702310.1	YiiX family permuted papain-like enzyme	-
OF379_RS22840 (OF379_22840)	rpmE	4748630..4748842 (-)	213	WP_000710769.1	50S ribosomal protein L31	-
OF379_RS22845 (OF379_22845)	priA	4749045..4751243 (+)	2199	WP_001469197.1	primosomal protein N'	Machinery gene
OF379_RS22850 (OF379_22850)	cytR	4751399..4752424 (+)	1026	WP_000644904.1	DNA-binding transcriptional regulator CytR	Regulator
OF379_RS22855 (OF379_22855)	ftsN	4752516..4753475 (+)	960	WP_000068834.1	cell division protein FtsN	-
OF379_RS22860 (OF379_22860)	hslV	4753568..4754098 (+)	531	WP_000208242.1	ATP-dependent protease subunit HslV	-
OF379_RS22865 (OF379_22865)	hslU	4754108..4755439 (+)	1332	WP_001293344.1	HslU--HslV peptidase ATPase subunit	-
OF379_RS22870 (OF379_22870)	menA	4755506..4756432 (+)	927	WP_000139496.1	1,4-dihydroxy-2-naphthoate polyprenyltransferase	-
OF379_RS22875 (OF379_22875)	rraA	4756525..4757010 (+)	486	WP_000872908.1	ribonuclease E activity regulator RraA	-
OF379_RS22880 (OF379_22880)	zapB	4757095..4757340 (-)	246	WP_001296623.1	septal ring assembly protein ZapB	-

Sequence

Protein

• Length: 341 a.a.
• Molecular weight: 37819.78 Da
• Isoelectric Point: 6.3842

>NTDB_id=643466 OF379_RS22850 WP_000644904.1 4751399..4752424(+) (cytR) [Escherichia coli strain SW4848]
MKAKKQETAATMKDVALKAKVSTATVSRALMNPDKVSQATRNRVEKAAREVGYLPQPMGRNVKRNESRTILVIVPDICDP
FFSEIIRGIEVTAANHGYLVLIGDCAHQNQQEKTFIDLIITKQIDGMLLLGSRLPFDASIEEQRNLPPMVMANEFAPELE
LPTVHIDNLTAAFDAVNYLYEQGHKRIGCIAGPEEMPLCHYRLQGYVQALRRCGIMVDPQYIARGDFTFEAGSKAMQQLL
DLPQPPTAVFCHSDVMALGALSQAKRQGLKVPEDLSIIGFDNIDLTQFCDPPLTTIAQPRYEIGREAMLLLLDQMQGQHV
GSGSRLMDCELIIRGSTRALP

Nucleotide

• Length: 1026 bp

>NTDB_id=643466 OF379_RS22850 WP_000644904.1 4751399..4752424(+) (cytR) [Escherichia coli strain SW4848]
GTGAAAGCGAAGAAGCAGGAAACTGCCGCGACCATGAAAGACGTTGCCCTCAAGGCAAAAGTCTCTACAGCGACTGTCTC
CCGAGCATTAATGAATCCCGATAAAGTCTCCCAGGCCACCCGTAATCGGGTTGAAAAAGCGGCCCGGGAAGTGGGTTATT
TACCGCAGCCTATGGGGCGCAACGTCAAGCGTAATGAATCCCGCACCATTCTGGTGATTGTCCCGGATATCTGCGATCCC
TTCTTTAGCGAAATTATTCGCGGTATCGAAGTTACGGCGGCAAATCACGGATATCTGGTGCTGATTGGCGACTGTGCGCA
TCAAAATCAGCAGGAAAAAACCTTTATCGATTTGATCATCACCAAGCAAATTGATGGCATGTTGTTGCTGGGTTCAAGGC
TGCCGTTTGATGCCAGCATTGAGGAACAGCGTAATCTGCCGCCGATGGTGATGGCGAACGAATTTGCACCGGAACTGGAG
CTGCCTACCGTTCATATCGACAATCTGACCGCCGCATTTGATGCAGTAAATTATTTATATGAGCAAGGGCATAAACGGAT
TGGCTGTATAGCCGGTCCCGAAGAGATGCCGCTGTGTCACTACCGCCTGCAAGGCTACGTTCAGGCGCTGCGTCGCTGCG
GCATTATGGTTGATCCGCAATACATCGCCCGTGGCGACTTCACCTTCGAAGCCGGAAGCAAAGCAATGCAACAGCTGCTT
GATCTTCCACAACCGCCTACTGCTGTCTTCTGCCATAGCGATGTGATGGCGCTCGGCGCACTTTCGCAGGCAAAACGCCA
GGGGCTGAAAGTACCGGAAGACCTTTCCATAATCGGTTTTGATAACATCGACCTGACGCAATTTTGTGATCCGCCGCTGA
CAACCATCGCGCAGCCGCGTTACGAAATCGGTCGGGAAGCTATGCTGTTATTGCTTGATCAAATGCAGGGGCAACACGTT
GGCAGTGGCTCTCGTTTAATGGACTGCGAACTTATCATCCGGGGATCAACACGCGCGTTACCTTAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (11-56)

• Periplasmic binding protein-like domain (Peripla_BP_3) (176-337)

3D structure

• AlphaFold DB: P0ACN8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cytR	Vibrio parahaemolyticus RIMD 2210633	64.179	98.24	0.63
cytR	Vibrio cholerae C6706	65.443	95.894	0.628