Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   U722_RS05615 Genome accession   NC_023073
Coordinates   1133745..1134401 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus amyloliquefaciens LFB112     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1128745..1139401
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U722_RS05590 (U722_05845) oppF 1129273..1130190 (+) 918 WP_003155037.1 oligopeptide ABC transporter ATP-binding protein OppF -
  U722_RS05595 (U722_05850) - 1130297..1131484 (+) 1188 WP_003155036.1 putative glycoside hydrolase -
  U722_RS05600 (U722_05855) - 1131603..1132181 (+) 579 WP_024085122.1 GNAT family N-acetyltransferase -
  U722_RS05605 (U722_05860) spx 1132360..1132755 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  U722_RS05610 (U722_05865) - 1132813..1133469 (-) 657 WP_003155033.1 TerC family protein -
  U722_RS19975 - 1133652..1133762 (+) 111 Protein_1058 adaptor protein MecA -
  U722_RS05615 (U722_05870) mecA 1133745..1134401 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  U722_RS05620 (U722_05880) - 1134552..1135712 (+) 1161 WP_024085124.1 competence protein CoiA family protein -
  U722_RS05625 (U722_05885) pepF 1135940..1137769 (+) 1830 WP_024085125.1 oligoendopeptidase F Regulator
  U722_RS19980 (U722_05890) - 1137807..1137974 (-) 168 WP_003155026.1 hypothetical protein -
  U722_RS05635 (U722_05895) spxH 1138260..1139162 (-) 903 WP_024085126.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=64183 U722_RS05615 WP_003155032.1 1133745..1134401(+) (mecA) [Bacillus amyloliquefaciens LFB112]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=64183 U722_RS05615 WP_003155032.1 1133745..1134401(+) (mecA) [Bacillus amyloliquefaciens LFB112]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTAGTGATCGCTGATCATGCGTTATATACAATAAAAA
AGCACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment