Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   LXN10_RS12105 Genome accession   NZ_CP090177
Coordinates   2404628..2406460 (-) Length   610 a.a.
NCBI ID   WP_375723248.1    Uniprot ID   -
Organism   Arcobacter sp. KX21116     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2399628..2411460
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LXN10_RS12080 (LXN10_12050) - 2400867..2401505 (-) 639 WP_375723243.1 adenylate kinase -
  LXN10_RS12085 (LXN10_12055) - 2401619..2402188 (+) 570 WP_375723244.1 adenylate kinase -
  LXN10_RS12090 (LXN10_12060) - 2402188..2402943 (+) 756 WP_375723245.1 competence/damage-inducible protein A -
  LXN10_RS12095 (LXN10_12065) - 2402940..2403590 (-) 651 WP_375723246.1 tetratricopeptide repeat protein -
  LXN10_RS12100 (LXN10_12070) - 2403587..2404609 (-) 1023 WP_375723247.1 alanine racemase -
  LXN10_RS12105 (LXN10_12075) uvrC 2404628..2406460 (-) 1833 WP_375723248.1 excinuclease ABC subunit UvrC Machinery gene
  LXN10_RS12110 (LXN10_12080) - 2406582..2406974 (+) 393 WP_375723249.1 tautomerase -
  LXN10_RS12115 (LXN10_12085) - 2407025..2407303 (+) 279 WP_375723250.1 antibiotic biosynthesis monooxygenase family protein -
  LXN10_RS12120 (LXN10_12090) - 2407317..2407787 (-) 471 WP_375723251.1 DnaJ domain-containing protein -
  LXN10_RS12125 (LXN10_12095) - 2408156..2408422 (+) 267 WP_375723252.1 DnaJ domain-containing protein -
  LXN10_RS12130 (LXN10_12100) - 2408434..2409303 (+) 870 WP_375723253.1 ADP-ribosylglycohydrolase family protein -
  LXN10_RS12135 (LXN10_12105) - 2409313..2409936 (-) 624 WP_375723254.1 DsbA family protein -
  LXN10_RS12140 (LXN10_12110) - 2410040..2410483 (+) 444 WP_375723255.1 hypothetical protein -
  LXN10_RS12145 (LXN10_12115) - 2410470..2411354 (+) 885 WP_375723256.1 radical SAM protein -

Sequence

Protein


Download         Length: 610 a.a.        Molecular weight: 70959.91 Da        Isoelectric Point: 8.8096

>NTDB_id=640950 LXN10_RS12105 WP_375723248.1 2404628..2406460(-) (uvrC) [Arcobacter sp. KX21116]
MDLENKLKQLPNDAGVYQYFDKDGHLLYVGKAKVLKNRVKSYFKFTPQLRPADKLGPRIYKMISEVKSCEWIVVPNEHDA
LILENSLIKQLKPKYNILLRDDKTYPYIYVDLNEDFPRLEITRKVLKGSNIKYFGPYSTGARDILDSIYETFPLVQKKSC
IKGKEACLFFQIKKCLAPCENRVSKEDYANILNDSMEYIYNKSKLISKLKVKMQEYSDDFRFEEAMKIRDRIKTIEKSEI
KTGMDLATNENLDIFAIKNINSKAVIVRMFIRDGKLASSSHDYLKSNVEETEEFDYEEAYKRAIINYYSNEIPIIPKEIL
IAKELEDIEDIKEFLKNKLVKKINIINPKLGKKKDIVDVALNNCDELLRIDSTKGANTLYEEIKELFNLSQIPNRVESFD
NSHMMGQATVGAMVVWDNDKFVKSDFRHYNLEAHDEYSQMREMLIRRVENFEKNPAPDLWVIDGGSTLLKLAYDIVESVG
VKLDIIAVAKEKIDFKAHRAKGAAKDIVHYKQGDEFVSIKLLTSDRRLHFVQRQRDEAHRFVINFHKKQKRAEDKQISLL
NIKGIGEAKVKKLLLYFGTFENIKEASVETLKEVLNEKDSILISNHFNQN

Nucleotide


Download         Length: 1833 bp        

>NTDB_id=640950 LXN10_RS12105 WP_375723248.1 2404628..2406460(-) (uvrC) [Arcobacter sp. KX21116]
ATGGATTTAGAAAACAAACTTAAACAGCTTCCAAATGATGCAGGTGTATATCAATACTTTGATAAAGATGGACATTTACT
TTATGTAGGAAAAGCAAAAGTTTTAAAAAATAGAGTTAAATCATACTTTAAATTTACTCCCCAACTTCGACCTGCTGATA
AACTAGGTCCTAGAATTTATAAAATGATAAGTGAAGTCAAATCATGTGAATGGATTGTAGTACCAAATGAACATGATGCA
CTAATTTTAGAAAATTCCCTAATAAAACAATTAAAACCAAAATATAATATTCTTCTTCGTGACGATAAAACTTACCCTTA
TATTTATGTTGATTTAAATGAGGATTTTCCAAGATTAGAGATTACAAGAAAAGTTTTAAAAGGCTCAAATATAAAATACT
TTGGTCCCTACTCAACTGGGGCTAGAGATATATTAGATTCAATATACGAAACCTTTCCACTTGTACAAAAAAAATCATGT
ATAAAAGGAAAAGAGGCTTGTTTATTTTTTCAAATCAAAAAATGTTTAGCTCCCTGTGAAAATAGAGTTTCGAAAGAAGA
TTATGCAAATATTTTAAATGATTCTATGGAGTATATTTACAACAAATCAAAACTAATCTCAAAACTTAAAGTAAAAATGC
AAGAGTATTCAGATGATTTTCGTTTTGAAGAGGCTATGAAAATAAGAGATAGAATAAAAACTATAGAAAAATCAGAGATA
AAAACGGGTATGGATTTAGCTACAAATGAAAACCTAGATATCTTTGCTATTAAAAATATCAACTCAAAAGCTGTGATTGT
AAGAATGTTTATTAGAGATGGGAAATTGGCTTCTTCTTCACATGATTATCTTAAGTCAAATGTAGAAGAAACTGAAGAGT
TTGATTACGAAGAAGCATATAAAAGAGCTATAATCAACTATTATTCAAATGAAATTCCTATCATTCCAAAAGAGATACTT
ATTGCTAAAGAACTTGAAGATATTGAAGATATAAAAGAGTTCTTAAAAAATAAACTTGTTAAAAAGATAAATATTATCAA
TCCAAAACTTGGAAAGAAAAAAGACATAGTAGATGTTGCTTTAAACAACTGTGACGAATTATTGAGAATAGATAGCACAA
AAGGTGCAAATACACTTTATGAAGAGATTAAAGAGTTATTTAATCTCTCTCAAATACCAAATAGAGTTGAAAGCTTTGAT
AACTCACATATGATGGGACAAGCAACTGTTGGTGCAATGGTTGTATGGGATAATGATAAATTTGTAAAAAGTGACTTTAG
ACACTACAACTTAGAAGCCCATGATGAATACTCACAAATGAGAGAGATGCTAATACGAAGAGTCGAAAACTTTGAAAAAA
ATCCTGCACCAGACTTATGGGTTATTGATGGTGGTTCTACTTTATTAAAACTTGCATATGACATAGTTGAATCAGTTGGA
GTAAAGCTAGATATTATTGCAGTTGCAAAAGAGAAAATTGATTTTAAAGCACATAGAGCAAAAGGTGCGGCAAAAGATAT
TGTGCATTATAAACAAGGTGATGAATTTGTTTCTATTAAATTATTGACTTCAGATAGAAGATTACACTTTGTACAAAGAC
AAAGGGATGAAGCCCATAGATTTGTTATTAATTTTCATAAAAAACAAAAAAGAGCAGAAGACAAACAAATATCTTTATTA
AATATAAAAGGTATTGGGGAAGCAAAGGTGAAAAAACTACTTCTTTATTTTGGAACTTTTGAGAATATAAAAGAGGCATC
TGTTGAAACTCTAAAAGAGGTTTTAAATGAAAAAGATAGTATTCTAATATCAAATCATTTTAATCAAAACTAA

Domains

Predicted by InterproScan.

UvrB/uvrC motif (UVR)

(204-237)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(384-543)

GIY-YIG catalytic domain (GIY-YIG)

(15-96)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

50.417

98.197

0.495