Detailed information NTG0640927

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: LXH20_RS16955
• Genome accession: NZ_CP090150
• Coordinates: 3476463..3477626 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain BR-01
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3471463..3482626

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LXH20_RS16925 (LXH20_16925)	-	3471728..3472147 (-)	420	WP_014419009.1	TIGR03826 family flagellar region protein	-
LXH20_RS16930 (LXH20_16930)	comFC	3472221..3472910 (-)	690	WP_197538213.1	ComF family protein	Machinery gene
LXH20_RS16935 (LXH20_16935)	-	3472916..3473200 (-)	285	WP_022553866.1	late competence development ComFB family protein	-
LXH20_RS16940 (LXH20_16940)	comFA	3473258..3474643 (-)	1386	WP_022553867.1	DEAD/DEAH box helicase	Machinery gene
LXH20_RS16945 (LXH20_16945)	-	3474751..3475599 (-)	849	WP_003151387.1	DegV family protein	-
LXH20_RS16950 (LXH20_16950)	degU	3475697..3476386 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
LXH20_RS16955 (LXH20_16955)	degS	3476463..3477626 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
LXH20_RS16960 (LXH20_16960)	-	3477849..3478496 (+)	648	WP_007407485.1	YigZ family protein	-
LXH20_RS16965 (LXH20_16965)	-	3478501..3479715 (+)	1215	WP_022553868.1	LCP family protein	-
LXH20_RS16970 (LXH20_16970)	-	3479815..3480891 (-)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
LXH20_RS16975 (LXH20_16975)	tuaH	3481023..3482219 (-)	1197	WP_022553869.1	teichuronic acid biosynthesis protein TuaH	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=640927 LXH20_RS16955 WP_007407484.1 3476463..3477626(-) (degS) [Bacillus velezensis strain BR-01]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=640927 LXH20_RS16955 WP_007407484.1 3476463..3477626(-) (degS) [Bacillus velezensis strain BR-01]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTTAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAGCAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTAGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCTGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951