Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ODQ18_RS12690 Genome accession   NZ_CP107039
Coordinates   2445345..2445986 (-) Length   213 a.a.
NCBI ID   WP_003244318.1    Uniprot ID   P96686
Organism   Bacillus subtilis strain 11060     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2440345..2450986
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ODQ18_RS12675 (ODQ18_12675) ydfK 2440849..2441538 (+) 690 WP_015252719.1 DUF554 domain-containing protein -
  ODQ18_RS12680 (ODQ18_12680) cesA 2441741..2442643 (+) 903 WP_003234180.1 carboxylesterase -
  ODQ18_RS12685 (ODQ18_12685) pleJ 2443055..2445229 (-) 2175 WP_041850750.1 MMPL family transporter -
  ODQ18_RS12690 (ODQ18_12690) vraR 2445345..2445986 (-) 642 WP_003244318.1 two-component system response regulator YdfI Regulator
  ODQ18_RS12695 (ODQ18_12695) ydfH 2445979..2447202 (-) 1224 WP_041850749.1 two-component system sensor histidine kinase YdfH -
  ODQ18_RS12700 (ODQ18_12700) - 2447466..2447609 (+) 144 WP_041850748.1 hypothetical protein -
  ODQ18_RS12705 (ODQ18_12705) - 2447606..2447785 (+) 180 WP_010886421.1 hypothetical protein -
  ODQ18_RS12710 (ODQ18_12710) ydfG 2447871..2448314 (+) 444 WP_014478970.1 carboxymuconolactone decarboxylase family protein -
  ODQ18_RS12715 (ODQ18_12715) ydfF 2448394..2449074 (-) 681 WP_003244115.1 ArsR/SmtB family transcription factor -
  ODQ18_RS12720 (ODQ18_12720) ydfE 2449164..2449787 (+) 624 WP_041850747.1 flavin reductase family protein -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23973.92 Da        Isoelectric Point: 5.4183

>NTDB_id=640289 ODQ18_RS12690 WP_003244318.1 2445345..2445986(-) (vraR) [Bacillus subtilis strain 11060]
MNKVLIVDDHLVVREGLKLLIETNDQYTIIGEAENGKVAVRLADELEPDIILMDLYMPEMSGLEAIKQIKEKHDTPIIIL
TTYNEDHLMIEGIELGAKGYLLKDTSSETLFHTMDAAIRGNVLLQPDILKRLQEIQFERMKKQRNETQLTEKEVIVLKAI
AKGLKSKAIAFDLGVSERTVKSRLTSIYNKLGANSRTEAVTIAMQKGILTIDN

Nucleotide


Download         Length: 642 bp        

>NTDB_id=640289 ODQ18_RS12690 WP_003244318.1 2445345..2445986(-) (vraR) [Bacillus subtilis strain 11060]
ATGAATAAGGTTTTAATCGTTGATGACCATCTTGTCGTGAGGGAAGGTCTGAAGCTTTTAATTGAAACGAATGATCAATA
CACCATTATAGGAGAGGCGGAAAATGGAAAAGTCGCAGTCCGTCTTGCAGATGAATTAGAACCGGATATCATTCTGATGG
ATTTGTATATGCCGGAGATGAGCGGGTTAGAGGCCATTAAACAAATAAAAGAAAAACACGATACCCCCATCATTATTTTG
ACTACATATAATGAAGATCACTTAATGATCGAAGGGATTGAATTAGGAGCGAAAGGATATCTGTTAAAGGATACGAGTTC
AGAAACCCTTTTTCACACAATGGATGCAGCGATCAGAGGAAATGTGCTGTTGCAGCCTGATATCCTCAAACGTCTGCAAG
AAATCCAATTTGAGCGGATGAAAAAGCAGCGCAATGAGACGCAGCTGACAGAAAAGGAAGTCATTGTTCTAAAAGCAATT
GCTAAAGGTCTTAAAAGCAAAGCGATTGCCTTTGATTTGGGCGTCTCTGAGCGAACAGTAAAGTCCAGATTAACGTCCAT
TTACAATAAATTAGGCGCGAATTCAAGAACTGAGGCAGTAACGATTGCCATGCAAAAAGGTATTCTGACAATAGACAACT
AA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Bacterial regulatory proteins, luxR family (GerE)

(148-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P96686

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

36.493

99.061

0.362