Detailed information NTG0640227

Bioinformatically predicted

Overview

• Name: comGA
• Type: Machinery gene
• Locus tag: FH104_RS10525
• Genome accession: NZ_CP090014
• Coordinates: 2105862..2106836 (+)
• Length: 324 a.a.
• NCBI ID: WP_049415532.1
• Uniprot ID: -
• Organism: Staphylococcus hominis strain acrlk
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2100862..2111836

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FH104_RS10490 (FH104_10465)	rpmG	2101322..2101471 (+)	150	WP_002449881.1	50S ribosomal protein L33	-
FH104_RS10495 (FH104_10470)	-	2101682..2102233 (+)	552	WP_017176231.1	5-formyltetrahydrofolate cyclo-ligase	-
FH104_RS10500 (FH104_10475)	-	2102233..2103690 (+)	1458	WP_017176232.1	rhomboid family protein	-
FH104_RS10505 (FH104_10480)	-	2103674..2103877 (+)	204	WP_017176233.1	YqgQ family protein	-
FH104_RS10510 (FH104_10485)	-	2103874..2104860 (+)	987	WP_002449785.1	ROK family glucokinase	-
FH104_RS10515 (FH104_10490)	-	2104860..2105183 (+)	324	WP_054105767.1	MTH1187 family thiamine-binding protein	-
FH104_RS10520 (FH104_10495)	-	2105185..2105811 (+)	627	WP_017176235.1	MBL fold metallo-hydrolase	-
FH104_RS10525 (FH104_10500)	comGA	2105862..2106836 (+)	975	WP_049415532.1	competence type IV pilus ATPase ComGA	Machinery gene
FH104_RS10530 (FH104_10505)	comGB	2106814..2107872 (+)	1059	WP_048681721.1	competence type IV pilus assembly protein ComGB	-
FH104_RS10535 (FH104_10510)	comGC	2107892..2108203 (+)	312	WP_017176238.1	competence type IV pilus major pilin ComGC	Machinery gene
FH104_RS10540 (FH104_10515)	comGD	2108193..2108627 (+)	435	WP_054105766.1	competence type IV pilus minor pilin ComGD	-
FH104_RS10545 (FH104_10520)	-	2108819..2109316 (+)	498	WP_017176240.1	competence protein ComG	-
FH104_RS10550 (FH104_10525)	-	2109481..2109990 (+)	510	WP_017176242.1	shikimate kinase	-
FH104_RS10555 (FH104_10530)	gcvT	2110185..2111276 (+)	1092	WP_017176243.1	glycine cleavage system aminomethyltransferase GcvT	-

Sequence

Protein

• Length: 324 a.a.
• Molecular weight: 36880.87 Da
• Isoelectric Point: 8.4444

>NTDB_id=640227 FH104_RS10525 WP_049415532.1 2105862..2106836(+) (comGA) [Staphylococcus hominis strain acrlk]
MKLLFQEIINKAISKNASDVHFIPSEDKVHIKFRVNDILETYEMFSNDIYEKLLIYMKFKANLDVSTHQIAQSGRYTYHA
KSIFYLRISTLPLSLGIESCVIRLIPQYFTSKREYKDFNDFKSLMNKKQGLILLTGPTGSGKSTLMYQLVLYAFQELNLN
VITIENPVEQLLKGITQVSVNHKAGIDYVSSFKAILRCDPDVILIGEIRDAEVAKCVIQASLSGHLVLTTMHSSNCKGAI
LRLLEMGISVQEISQAINVISNQRLVTTTSNQRKLVCESITNNQIQYFFEHNHTLPKTFNNLKEKLLSLSKEGLICEDVV
EKYI

Nucleotide

• Length: 975 bp

>NTDB_id=640227 FH104_RS10525 WP_049415532.1 2105862..2106836(+) (comGA) [Staphylococcus hominis strain acrlk]
TTGAAATTATTATTTCAAGAAATAATTAATAAAGCAATTTCAAAAAATGCAAGTGACGTACACTTTATTCCTTCAGAGGA
TAAAGTACATATTAAATTCAGAGTGAATGATATATTAGAGACATATGAAATGTTTAGTAATGACATTTATGAAAAATTAT
TAATTTATATGAAATTTAAAGCAAATTTAGATGTATCAACACATCAAATAGCTCAAAGTGGTAGATATACTTATCATGCT
AAATCAATATTTTATTTAAGAATTTCTACTTTACCTTTGTCATTAGGAATAGAAAGTTGTGTTATTAGACTTATCCCTCA
ATATTTCACTTCTAAAAGAGAGTATAAGGACTTTAATGACTTTAAATCTCTAATGAATAAAAAGCAAGGTCTCATTTTAC
TTACTGGTCCAACAGGTTCAGGTAAAAGTACTTTGATGTATCAATTAGTACTCTATGCTTTTCAAGAATTAAATTTAAAT
GTTATTACAATTGAAAATCCTGTTGAACAATTATTAAAAGGCATAACACAAGTGTCAGTAAATCATAAAGCCGGTATAGA
TTATGTTAGTTCATTTAAAGCAATATTAAGATGTGATCCAGATGTTATTTTAATTGGTGAAATTAGAGATGCTGAAGTGG
CAAAATGTGTTATTCAAGCAAGTTTAAGTGGTCATTTAGTGCTCACTACTATGCATTCAAGCAATTGTAAGGGCGCAATA
CTCAGATTGTTAGAGATGGGGATTAGTGTTCAAGAAATTTCACAAGCAATAAATGTTATTTCAAATCAAAGATTAGTTAC
AACTACTTCAAATCAAAGAAAGCTTGTTTGTGAGTCTATTACAAATAATCAAATTCAATATTTTTTTGAACATAACCATA
CGCTTCCTAAGACATTTAATAATTTAAAAGAAAAATTGTTATCGCTATCGAAAGAAGGTCTTATATGTGAAGATGTGGTT
GAAAAATATATTTAA

Domains

Predicted by InterproScan.

• Type II/IV secretion system protein (T2SSE) (7-267)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGA	Staphylococcus aureus MW2	69.136	100	0.691
comGA	Staphylococcus aureus N315	69.136	100	0.691