Detailed information NTG0640007

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: LV622_RS13090
• Genome accession: NZ_CP090001
• Coordinates: 2636046..2636933 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain RN6390
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2631046..2641933

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LV622_RS13060 (LV622_13060)	-	2631065..2631157 (+)	93	WP_010956583.1	hypothetical protein	-
LV622_RS13065 (LV622_13065)	-	2631265..2631762 (-)	498	WP_001065268.1	glutathione peroxidase	-
LV622_RS13070 (LV622_13070)	-	2631772..2632032 (-)	261	WP_001789910.1	hypothetical protein	-
LV622_RS13075 (LV622_13075)	-	2632414..2632527 (-)	114	WP_011447078.1	hypothetical protein	-
LV622_RS13080 (LV622_13080)	-	2633186..2635186 (-)	2001	WP_000776751.1	ABC transporter permease	-
LV622_RS13085 (LV622_13085)	-	2635183..2635938 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
LV622_RS13090 (LV622_13090)	braS	2636046..2636933 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
LV622_RS13095 (LV622_13095)	braR	2636944..2637609 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
LV622_RS13100 (LV622_13100)	-	2637635..2637835 (-)	201	WP_000604728.1	hypothetical protein	-
LV622_RS13105 (LV622_13105)	-	2638033..2639457 (+)	1425	WP_000953744.1	alkaline phosphatase	-
LV622_RS13635	-	2639517..2639618 (-)	102	WP_000731972.1	SE2200 family small protein	-
LV622_RS13115 (LV622_13115)	-	2639740..2640195 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
LV622_RS13120 (LV622_13120)	-	2640440..2641201 (-)	762	WP_000323455.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=640007 LV622_RS13090 WP_000143419.1 2636046..2636933(-) (braS) [Staphylococcus aureus strain RN6390]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=640007 LV622_RS13090 WP_000143419.1 2636046..2636933(-) (braS) [Staphylococcus aureus strain RN6390]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997