Detailed information NTG0639440

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: LXA49_RS09580
• Genome accession: NZ_CP089949
• Coordinates: 1865207..1866244 (-)
• Length: 345 a.a.
• NCBI ID: WP_001813016.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain SN75752
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1860207..1871244

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LXA49_RS09555 (LXA49_09540)	-	1860946..1862277 (-)	1332	WP_000390042.1	hemolysin family protein	-
LXA49_RS09560 (LXA49_09545)	endA	1862568..1863392 (-)	825	WP_001036791.1	DNA-entry nuclease EndA	Machinery gene
LXA49_RS09565 (LXA49_09550)	-	1863431..1863619 (-)	189	WP_001036519.1	DNA-directed RNA polymerase subunit beta	-
LXA49_RS09570 (LXA49_09555)	murA	1863612..1864895 (-)	1284	WP_000358032.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
LXA49_RS09575 (LXA49_09560)	-	1864919..1865149 (-)	231	WP_000250390.1	DUF1146 family protein	-
LXA49_RS09580 (LXA49_09565)	sepM	1865207..1866244 (-)	1038	WP_001813016.1	SepM family pheromone-processing serine protease	Regulator
LXA49_RS09585 (LXA49_09570)	coaD	1866228..1866716 (-)	489	WP_001280746.1	pantetheine-phosphate adenylyltransferase	-
LXA49_RS09590 (LXA49_09575)	rsmD	1866706..1867245 (-)	540	WP_000706963.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
LXA49_RS09595 (LXA49_09580)	asnA	1867310..1868302 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
LXA49_RS09600 (LXA49_09585)	-	1868414..1869097 (-)	684	WP_001016913.1	Bax inhibitor-1/YccA family protein	-
LXA49_RS09605 (LXA49_09590)	-	1869153..1869893 (-)	741	WP_000152679.1	RNA methyltransferase	-
LXA49_RS09610 (LXA49_09595)	-	1869927..1870205 (+)	279	WP_001174614.1	acylphosphatase	-
LXA49_RS09615 (LXA49_09600)	yidC	1870283..1871209 (+)	927	WP_000835955.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37609.64 Da
• Isoelectric Point: 4.9590

>NTDB_id=639440 LXA49_RS09580 WP_001813016.1 1865207..1866244(-) (sepM) [Streptococcus pneumoniae strain SN75752]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKEIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIDLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=639440 LXA49_RS09580 WP_001813016.1 1865207..1866244(-) (sepM) [Streptococcus pneumoniae strain SN75752]
ATGAAAAAAAAGATTAGATGGCCTTTGTATGTCATTGCGGCCTTGATTGTGACCTTCTTGGCATTTGTGGTGCCTTTGCC
CTACTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCTACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGAAATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGACTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAGATTATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGACTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGTCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.357	99.13	0.588