Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   LXA46_RS09350 Genome accession   NZ_CP089948
Coordinates   1867658..1868695 (-) Length   345 a.a.
NCBI ID   WP_000727277.1    Uniprot ID   A0A0B7LHQ0
Organism   Streptococcus pneumoniae TIGR4     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 1862658..1873695
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LXA46_RS09325 (LXA46_09310) - 1863459..1864790 (-) 1332 WP_000390039.1 hemolysin family protein -
  LXA46_RS09330 (LXA46_09315) endA 1865019..1865843 (-) 825 WP_001036779.1 DNA-entry nuclease EndA Machinery gene
  LXA46_RS09335 (LXA46_09320) - 1865882..1866070 (-) 189 WP_001036519.1 DNA-directed RNA polymerase subunit beta -
  LXA46_RS09340 (LXA46_09325) murA 1866063..1867346 (-) 1284 WP_000358028.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  LXA46_RS09345 (LXA46_09330) - 1867370..1867600 (-) 231 WP_000250384.1 DUF1146 family protein -
  LXA46_RS09350 (LXA46_09335) sepM 1867658..1868695 (-) 1038 WP_000727277.1 SepM family pheromone-processing serine protease Regulator
  LXA46_RS09355 (LXA46_09340) coaD 1868679..1869167 (-) 489 WP_001280753.1 pantetheine-phosphate adenylyltransferase -
  LXA46_RS09360 (LXA46_09345) rsmD 1869157..1869696 (-) 540 WP_000706963.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  LXA46_RS09365 (LXA46_09350) asnA 1869761..1870753 (-) 993 WP_000747993.1 aspartate--ammonia ligase -
  LXA46_RS09370 (LXA46_09355) - 1870865..1871548 (-) 684 WP_001016917.1 Bax inhibitor-1/YccA family protein -
  LXA46_RS09375 (LXA46_09360) - 1871604..1872344 (-) 741 WP_000152703.1 RNA methyltransferase -
  LXA46_RS09380 (LXA46_09365) - 1872378..1872656 (+) 279 WP_001174612.1 acylphosphatase -
  LXA46_RS09385 (LXA46_09370) yidC 1872734..1873660 (+) 927 WP_000835955.1 membrane protein insertase YidC -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 37537.57 Da        Isoelectric Point: 5.0724

>NTDB_id=639357 LXA46_RS09350 WP_000727277.1 1867658..1868695(-) (sepM) [Streptococcus pneumoniae TIGR4]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=639357 LXA46_RS09350 WP_000727277.1 1867658..1868695(-) (sepM) [Streptococcus pneumoniae TIGR4]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAAATCATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGTCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(130-193)

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(230-296)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7LHQ0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

59.649

99.13

0.591