Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   SLV14_RS17345 Genome accession   NZ_CP106840
Coordinates   4032881..4033549 (+) Length   222 a.a.
NCBI ID   WP_208681831.1    Uniprot ID   -
Organism   Streptomyces sp. Je 1-4     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4027881..4038549
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SLV14_RS17330 (SLV14_003475) - 4029324..4029716 (+) 393 WP_026169715.1 RidA family protein -
  SLV14_RS17335 (SLV14_003476) - 4030020..4031282 (-) 1263 WP_259670381.1 acyltransferase family protein -
  SLV14_RS17340 (SLV14_003477) - 4031645..4032529 (-) 885 WP_263270003.1 glycerophosphodiester phosphodiesterase -
  SLV14_RS17345 (SLV14_003478) vraR 4032881..4033549 (+) 669 WP_208681831.1 response regulator Regulator
  SLV14_RS17350 (SLV14_003479) - 4033606..4034811 (+) 1206 WP_259670382.1 sensor histidine kinase -
  SLV14_RS17355 (SLV14_003480) - 4034899..4035327 (+) 429 WP_263270005.1 hypothetical protein -
  SLV14_RS17360 (SLV14_003481) - 4035496..4035987 (+) 492 WP_263270006.1 hypothetical protein -
  SLV14_RS17365 (SLV14_003482) - 4036003..4036467 (+) 465 WP_263270007.1 hypothetical protein -
  SLV14_RS17370 (SLV14_003483) - 4036464..4037141 (+) 678 WP_208681839.1 response regulator transcription factor -
  SLV14_RS17375 (SLV14_003484) - 4037147..4038349 (+) 1203 WP_263270009.1 sensor histidine kinase -

Sequence

Protein


Download         Length: 222 a.a.        Molecular weight: 24214.14 Da        Isoelectric Point: 10.7915

>NTDB_id=638488 SLV14_RS17345 WP_208681831.1 4032881..4033549(+) (vraR) [Streptomyces sp. Je 1-4]
MTIRLLIADDQEMVRRGIRRIVESQPDMEVVGEAANGLDAVAMGRALKPDVALVDIRMPRMDGLEVTRRLADPALADPVR
IVIVTTFDLDEYVYPALRFGASGFLLKRSGPTLLVEAVRAAMAGDSLISPSVTVRLLRHVTGPTAGRRPRRRDAVLTERE
VEIAGKVAEGKTNADIARELFISAGTVKTHVASIQRKLQVRNRVGIAVRAWELGYATGRTPG

Nucleotide


Download         Length: 669 bp        

>NTDB_id=638488 SLV14_RS17345 WP_208681831.1 4032881..4033549(+) (vraR) [Streptomyces sp. Je 1-4]
GTGACGATTCGCTTATTGATCGCCGACGACCAGGAGATGGTCCGCCGGGGAATACGCCGCATCGTGGAGAGCCAGCCCGA
CATGGAAGTGGTCGGCGAGGCGGCGAACGGCCTGGACGCCGTGGCGATGGGGCGCGCGCTGAAGCCGGATGTGGCGCTGG
TGGACATCCGGATGCCGCGGATGGACGGCCTGGAGGTGACCCGCCGGCTGGCGGACCCCGCGCTGGCCGACCCGGTCCGG
ATCGTCATCGTGACCACCTTCGACCTCGATGAATACGTCTATCCCGCGCTGCGCTTCGGCGCCTCCGGCTTTCTGCTCAA
GCGCTCGGGGCCGACGCTGCTGGTCGAGGCGGTCCGGGCGGCGATGGCCGGCGACAGTCTGATCAGCCCCTCGGTCACCG
TCCGGCTGCTGCGGCATGTCACCGGCCCCACGGCCGGCCGCCGCCCCCGCCGCCGCGACGCGGTGCTGACCGAGCGGGAG
GTGGAGATCGCCGGGAAGGTCGCCGAGGGGAAGACCAATGCCGATATCGCCCGGGAGTTGTTCATCTCGGCGGGCACCGT
GAAGACCCATGTCGCCAGCATTCAGCGCAAGCTGCAGGTCCGTAACCGGGTCGGAATCGCCGTACGGGCCTGGGAGTTGG
GATATGCCACGGGGCGGACACCGGGGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(6-119)

Bacterial regulatory proteins, luxR family (GerE)

(155-209)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

37.383

96.396

0.36