Detailed information NTG0638484

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: SLV14_RS16880
• Genome accession: NZ_CP106840
• Coordinates: 3934845..3935969 (+)
• Length: 374 a.a.
• NCBI ID: WP_026170238.1
• Uniprot ID: A0A640THM3
• Organism: Streptomyces sp. Je 1-4
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 3929845..3940969

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SLV14_RS16865 (SLV14_003382)	-	3930395..3931258 (+)	864	WP_208681699.1	hypothetical protein	-
SLV14_RS16870 (SLV14_003383)	-	3931310..3933058 (-)	1749	WP_263269929.1	sigma-70 family RNA polymerase sigma factor	-
SLV14_RS16875 (SLV14_003384)	radA	3933307..3934719 (+)	1413	WP_263269931.1	DNA repair protein RadA	Machinery gene
SLV14_RS16880 (SLV14_003385)	disA	3934845..3935969 (+)	1125	WP_026170238.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
SLV14_RS16885 (SLV14_003386)	-	3935994..3936497 (-)	504	WP_411577458.1	pyridoxamine 5'-phosphate oxidase family protein	-
SLV14_RS16890 (SLV14_003387)	-	3936579..3937904 (-)	1326	WP_263269933.1	globin domain-containing protein	-
SLV14_RS16895 (SLV14_003388)	-	3938187..3938888 (+)	702	WP_263269935.1	response regulator transcription factor	-
SLV14_RS16900 (SLV14_003389)	-	3938995..3940629 (-)	1635	WP_263273191.1	GAF domain-containing protein	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40289.13 Da
• Isoelectric Point: 4.9306

>NTDB_id=638484 SLV14_RS16880 WP_026170238.1 3934845..3935969(+) (disA) [Streptomyces sp. Je 1-4]
MAANDRASTPGRSGGSSSTESLMRASLSAVAPGTALRDGLERILRGNTGGLIVLGFDKTVETMCTGGFVLDVEFTATRLR
ELCKLDGALVLDKDITKILRAGVQLVPDASIPTEETGTRHRTAQRVSIQAGFPVVSVSQSMRLIALYVDGERRVLEESAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLEELIA
GVEPERELVVRDYVPEPTAKRSRTVAEALAELDALSHTELLELPIVARALGYSGAPETLDSAVSPRGFRLLAKVPRLPGT
VIDRLVDHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=638484 SLV14_RS16880 WP_026170238.1 3934845..3935969(+) (disA) [Streptomyces sp. Je 1-4]
GTGGCAGCCAACGACCGGGCATCGACTCCCGGCAGGTCCGGTGGCAGTTCCTCCACCGAGAGCCTGATGCGCGCCTCGCT
GAGCGCCGTCGCGCCCGGTACGGCCCTGCGCGACGGACTGGAGCGCATCCTGCGCGGCAACACCGGCGGACTGATCGTGC
TGGGCTTCGACAAGACCGTCGAAACCATGTGCACCGGCGGATTCGTCCTCGACGTGGAGTTCACCGCGACCCGGCTGCGC
GAGCTGTGCAAGCTCGACGGTGCGCTGGTCCTCGACAAGGACATCACCAAGATCCTGCGGGCCGGTGTCCAGCTGGTCCC
GGACGCCTCCATCCCGACGGAGGAGACCGGCACCCGCCACCGCACCGCCCAGCGCGTCTCCATCCAGGCCGGCTTCCCGG
TCGTCTCCGTCAGCCAGTCGATGCGCCTGATCGCCCTCTACGTCGACGGCGAGCGCCGCGTCCTGGAGGAGTCGGCCGCG
ATCCTCTCCCGCGCCAACCAGGCCCTGGCGACCCTGGAGCGCTACAAGCTCCGCCTGGACGAGGTCGCCGGCACCCTCTC
CGCCCTGGAGATCGAGGACTTGGTGACGGTCCGCGATGTCACCGCGGTCGCCCAGCGCCTGGAGATGGTCCGCCGGATCG
CCACCGAGATCGCCGAGTACGTCGTCGAACTCGGCACGGACGGCCGGCTGCTCGCCCTCCAGCTGGAGGAGCTGATCGCC
GGCGTGGAGCCCGAGCGGGAGCTGGTCGTCCGCGACTACGTCCCCGAGCCGACCGCCAAGCGCTCCCGTACGGTCGCCGA
GGCGCTCGCCGAGCTGGACGCCCTCAGCCACACCGAGCTCCTCGAACTCCCCATCGTGGCCCGCGCGCTGGGCTACAGCG
GCGCCCCCGAGACCCTGGACTCCGCGGTCTCGCCGCGCGGCTTCCGCCTGCTGGCGAAGGTCCCCCGGCTGCCCGGCACG
GTCATCGACCGCCTCGTCGACCACTTCGGCGGCCTGCAGAAGCTCCTCGCGGCCAGCGTCGACGACCTCCAGACGGTCGA
CGGCGTCGGCGAGGCCCGCGCCCGCTCGGTCCGCGAGGGCCTGTCGCGGCTCGCGGAGTCGTCGATCCTGGAGCGGTACG
TCTGA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-296)

3D structure

• AlphaFold DB: A0A640THM3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	45.665	92.513	0.422