Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   LUU82_RS13670 Genome accession   NZ_CP089586
Coordinates   2746717..2747433 (-) Length   238 a.a.
NCBI ID   WP_000688498.1    Uniprot ID   Q2VG52
Organism   Staphylococcus aureus strain E1185_IV_ST12     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2741717..2752433
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LUU82_RS13650 (LUU82_13650) - 2742809..2743759 (+) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -
  LUU82_RS13655 (LUU82_13655) - 2743908..2745392 (+) 1485 WP_000141416.1 sucrose-6-phosphate hydrolase -
  LUU82_RS13660 (LUU82_13660) - 2745389..2746348 (+) 960 WP_001253309.1 carbohydrate kinase family protein -
  LUU82_RS13665 (LUU82_13665) - 2746536..2746645 (-) 110 Protein_2658 hypothetical protein -
  LUU82_RS13670 (LUU82_13670) agrA 2746717..2747433 (-) 717 WP_000688498.1 quorum-sensing response regulator AgrA Regulator
  LUU82_RS13675 (LUU82_13675) agrC 2747452..2748735 (-) 1284 WP_000447893.1 quorum-sensing sensor histidine kinase AgrC -
  LUU82_RS13680 (LUU82_13680) agrD 2748765..2748908 (-) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  LUU82_RS13685 (LUU82_13685) - 2748911..2749474 (-) 564 WP_001105696.1 accessory gene regulator AgrB -
  LUU82_RS13690 (LUU82_13690) hld 2749764..2749844 (+) 81 WP_000046022.1 delta-hemolysin -
  LUU82_RS13695 (LUU82_13695) - 2750444..2751229 (-) 786 WP_000867951.1 carbon-nitrogen family hydrolase -
  LUU82_RS13700 (LUU82_13700) - 2751590..2752216 (-) 627 WP_000522376.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.91 Da        Isoelectric Point: 6.0927

>NTDB_id=638163 LUU82_RS13670 WP_000688498.1 2746717..2747433(-) (agrA) [Staphylococcus aureus strain E1185_IV_ST12]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=638163 LUU82_RS13670 WP_000688498.1 2746717..2747433(-) (agrA) [Staphylococcus aureus strain E1185_IV_ST12]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGTTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2VG52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996