Detailed information NTG0063781

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: U712_RS17305
• Genome accession: NC_022898
• Coordinates: 3463233..3464390 (-)
• Length: 385 a.a.
• NCBI ID: WP_003227983.1
• Uniprot ID: A0A199WDV9
• Organism: Bacillus subtilis PY79
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3458233..3469390

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
U712_RS17275 (U712_17770)	yvyF	3458486..3458905 (-)	420	WP_003227995.1	TIGR03826 family flagellar region protein	-
U712_RS17280 (U712_17775)	comFC	3458979..3459701 (-)	723	WP_003227991.1	comF operon protein ComFC	Machinery gene
U712_RS17285 (U712_17780)	comFB	3459665..3459961 (-)	297	WP_003227989.1	late competence protein ComFB	-
U712_RS17290 (U712_17785)	comFA	3460021..3461412 (-)	1392	WP_003243962.1	ATP-dependent helicase ComFA	Machinery gene
U712_RS17295 (U712_17790)	fakBA	3461518..3462363 (-)	846	WP_003244125.1	DegV family protein	-
U712_RS17300 (U712_17795)	degU	3462461..3463150 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
U712_RS17305 (U712_17800)	degS	3463233..3464390 (-)	1158	WP_003227983.1	two-component sensor histidine kinase DegS	Regulator
U712_RS17310 (U712_17805)	yvyE	3464607..3465260 (+)	654	WP_003227979.1	YigZ family protein	-
U712_RS17315 (U712_17810)	tagV	3465260..3466435 (+)	1176	WP_003244117.1	polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagV	-
U712_RS17320 (U712_17815)	tagO	3466508..3467584 (-)	1077	WP_003227975.1	MraY family glycosyltransferase	-
U712_RS17325 (U712_17820)	tuaH	3467729..3468922 (-)	1194	WP_003243252.1	glycosyltransferase family 1 protein	-

Sequence

Protein

• Length: 385 a.a.
• Molecular weight: 44957.76 Da
• Isoelectric Point: 6.2957

>NTDB_id=63781 U712_RS17305 WP_003227983.1 3463233..3464390(-) (degS) [Bacillus subtilis PY79]
MNKTKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVQTRHARNRLSEVSR
NFHRFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLREVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGAEDGFQEIKNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGETEDQRLAPQFEVALFRLAQEAVSNALKHSESEEITVKVEI
TKDFVILMIKDNGKGFDLKEAKEKKNKSFGLLGMKERVDLLEGTMTIDSKIGLGTFIMIKVPLSL

Nucleotide

• Length: 1158 bp

>NTDB_id=63781 U712_RS17305 WP_003227983.1 3463233..3464390(-) (degS) [Bacillus subtilis PY79]
ATGAATAAAACAAAGATGGATTCCAAAGTGCTGGATTCTATTTTGATGAAGATGCTGAAAACCGTTGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGGGAGCAGTCACGCCAGCAGTATGAACAGCTGGTCGAAGAACTGAAACAAATTAAACAGCAGG
TGTATGAAGTGATTGAGCTTGGCGATAAACTTGAAGTGCAAACTCGCCATGCGAGAAACCGTTTATCCGAGGTCAGCCGT
AATTTTCATAGATTCAGTGAAGAGGAAATCCGCAATGCTTATGAAAAAGCCCATAAGCTGCAGGTAGAATTGACGATGAT
CCAGCAGCGTGAGAAGCAATTGCGCGAACGGCGGGACGATTTGGAGCGCAGATTGCTAGGGCTTCAGGAAATCATTGAGC
GGTCAGAATCATTAGTAAGCCAAATTACAGTTGTGCTCAACTACTTGAATCAGGATTTGCGCGAAGTTGGACTGCTTCTT
GCTGATGCTCAGGCAAAACAGGATTTCGGCTTAAGAATTATTGAGGCGCAGGAAGAAGAGCGAAAAAGAGTCTCAAGAGA
AATCCATGACGGACCCGCTCAAATGCTGGCGAATGTTATGATGAGATCGGAATTAATCGAGCGGATTTTCCGTGACCGGG
GCGCAGAGGACGGATTCCAAGAAATTAAAAATCTCCGCCAAAATGTTCGGAATGCCCTTTACGAAGTGAGAAGGATTATA
TATGATTTAAGACCGATGGCCCTTGATGACCTAGGCCTGATTCCAACTTTAAGAAAATATCTATATACAACCGAGGAATA
TAACGGGAAGGTCAAAATACATTTTCAGTGCATTGGAGAAACAGAGGATCAGAGGCTAGCGCCTCAGTTTGAGGTTGCGC
TCTTCAGGCTCGCACAGGAAGCTGTGTCTAATGCGCTAAAGCATTCTGAATCTGAAGAAATTACAGTCAAAGTTGAGATC
ACAAAGGATTTTGTGATTTTAATGATAAAAGATAACGGTAAAGGGTTCGACCTGAAGGAAGCGAAAGAGAAGAAAAACAA
ATCATTCGGCTTGCTGGGCATGAAAGAAAGAGTAGATTTATTGGAAGGAACGATGACAATAGATTCGAAAATAGGTCTTG
GGACATTTATTATGATTAAGGTTCCGTTATCTCTTTGA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (180-248)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

3D structure

• AlphaFold DB: A0A199WDV9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	100	100	1