Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   LUZ01_RS14100 Genome accession   NZ_CP089504
Coordinates   2842514..2843230 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain 3581_IA_ST247     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2837514..2848230
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LUZ01_RS14080 - 2838608..2839558 (+) 951 WP_000790330.1 LacI family DNA-binding transcriptional regulator -
  LUZ01_RS14085 - 2839707..2841191 (+) 1485 WP_023487214.1 sucrose-6-phosphate hydrolase -
  LUZ01_RS14090 - 2841188..2842147 (+) 960 WP_001253312.1 carbohydrate kinase -
  LUZ01_RS14095 - 2842335..2842442 (-) 108 WP_033841749.1 hypothetical protein -
  LUZ01_RS14100 agrA 2842514..2843230 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  LUZ01_RS14105 agrC 2843249..2844541 (-) 1293 WP_001554031.1 quorum-sensing sensor histidine kinase AgrC -
  LUZ01_RS14110 agrD 2844566..2844706 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  LUZ01_RS14115 agrB 2844703..2845272 (-) 570 WP_001105707.1 accessory gene regulator AgrB -
  LUZ01_RS14120 hld 2845562..2845642 (+) 81 WP_000046022.1 delta-hemolysin -
  LUZ01_RS14125 - 2846239..2847024 (-) 786 WP_000867960.1 carbon-nitrogen family hydrolase -
  LUZ01_RS14130 - 2847385..2848011 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=637756 LUZ01_RS14100 WP_000688492.1 2842514..2843230(-) (agrA) [Staphylococcus aureus strain 3581_IA_ST247]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=637756 LUZ01_RS14100 WP_000688492.1 2842514..2843230(-) (agrA) [Staphylococcus aureus strain 3581_IA_ST247]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1