Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   LUY93_RS09640 Genome accession   NZ_CP089500
Coordinates   1873854..1874570 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain 3144_IIV_ST8     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1868854..1879570
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LUY93_RS09610 - 1869073..1869699 (+) 627 WP_000522384.1 nitroreductase family protein -
  LUY93_RS09615 - 1870060..1870845 (+) 786 WP_000867960.1 carbon-nitrogen family hydrolase -
  LUY93_RS09620 hld 1871442..1871522 (-) 81 WP_000046022.1 delta-hemolysin -
  LUY93_RS09625 agrB 1871812..1872381 (+) 570 WP_001105707.1 accessory gene regulator AgrB -
  LUY93_RS09630 agrD 1872378..1872518 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  LUY93_RS09635 agrC 1872543..1873835 (+) 1293 WP_001554031.1 quorum-sensing sensor histidine kinase AgrC -
  LUY93_RS09640 agrA 1873854..1874570 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  LUY93_RS09645 - 1874642..1874749 (+) 108 WP_001790167.1 hypothetical protein -
  LUY93_RS09650 - 1874937..1875896 (-) 960 WP_001253313.1 carbohydrate kinase -
  LUY93_RS09655 - 1875893..1877377 (-) 1485 WP_000141417.1 sucrose-6-phosphate hydrolase -
  LUY93_RS09660 - 1877526..1878476 (-) 951 WP_000790330.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=637663 LUY93_RS09640 WP_000688492.1 1873854..1874570(+) (agrA) [Staphylococcus aureus strain 3144_IIV_ST8]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=637663 LUY93_RS09640 WP_000688492.1 1873854..1874570(+) (agrA) [Staphylococcus aureus strain 3144_IIV_ST8]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1