Detailed information
Bioinformatically predicted
Overview
| Name | ccrA | Type | Machinery gene |
| Locus tag | LUY91_RS10670 | Genome accession | NZ_CP089495 |
| Coordinates | 2100759..2102105 (+) | Length | 448 a.a. |
| NCBI ID | WP_000816499.1 | Uniprot ID | Q9R3W9 |
| Organism | Staphylococcus aureus strain E1202_II_ST496 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| SCCmec | 2100759..2156362 | 2100759..2102105 | within | 0 |
Gene organization within MGE regions
Location: 2100759..2156362
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LUY91_RS10670 | ccrA | 2100759..2102105 (+) | 1347 | WP_000816499.1 | cassette chromosome recombinase CcrA | Machinery gene |
| LUY91_RS10675 | ccrB | 2102126..2103754 (+) | 1629 | WP_001186596.1 | cassette chromosome recombinase CcrB | Machinery gene |
| LUY91_RS10680 | - | 2104225..2104575 (+) | 351 | WP_000171449.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| LUY91_RS10685 | - | 2104660..2104971 (+) | 312 | WP_000833212.1 | DUF960 family protein | - |
| LUY91_RS10690 | - | 2104990..2105511 (+) | 522 | WP_000836008.1 | DUF1643 domain-containing protein | - |
| LUY91_RS10695 | - | 2105513..2105719 (+) | 207 | WP_001077283.1 | hypothetical protein | - |
| LUY91_RS10700 | - | 2105712..2106035 (+) | 324 | WP_000088091.1 | JAB domain-containing protein | - |
| LUY91_RS10705 | - | 2106230..2108122 (+) | 1893 | WP_002485298.1 | site-specific integrase | - |
| LUY91_RS10710 | - | 2108129..2108506 (+) | 378 | WP_001041908.1 | DUF6262 family protein | - |
| LUY91_RS10715 | - | 2108744..2109109 (+) | 366 | WP_000159127.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| LUY91_RS10720 | - | 2109102..2111516 (+) | 2415 | WP_000378487.1 | cadmium-translocating P-type ATPase CadA | - |
| LUY91_RS10725 | - | 2111597..2112214 (+) | 618 | WP_000562107.1 | CadD family cadmium resistance transporter | - |
| LUY91_RS10730 | - | 2112488..2113126 (-) | 639 | Protein_2084 | sulfite exporter TauE/SafE family protein | - |
| LUY91_RS10735 | cstR | 2113126..2113386 (-) | 261 | WP_000220507.1 | persulfide-sensing transcriptional repressor CstR | - |
| LUY91_RS10740 | - | 2113522..2114586 (+) | 1065 | WP_000438836.1 | DsrE/DsrF/DrsH-like family protein | - |
| LUY91_RS10745 | cstB | 2114619..2115953 (+) | 1335 | Protein_2087 | persulfide dioxygenase-sulfurtransferase CstB | - |
| LUY91_RS10750 | - | 2116067..2117176 (-) | 1110 | WP_000943131.1 | ROK family transcriptional regulator | - |
| LUY91_RS10755 | psm-mec | 2117535..2117603 (+) | 69 | WP_014532405.1 | phenol-soluble modulin PSM-mec | - |
| LUY91_RS10760 | mecI | 2117688..2118059 (-) | 372 | Protein_2090 | mecA-type methicillin resistance repressor MecI | - |
| LUY91_RS10765 | - | 2118059..2119650 (-) | 1592 | Protein_2091 | BlaR1 family beta-lactam sensor/signal transducer | - |
| LUY91_RS10770 | mecA | 2119747..2121756 (+) | 2010 | WP_078056515.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| LUY91_RS10775 | - | 2121802..2122230 (-) | 429 | WP_000872606.1 | MaoC family dehydratase | - |
| LUY91_RS10780 | - | 2122327..2123070 (-) | 744 | WP_000958858.1 | glycerophosphoryl diester phosphodiesterase | - |
| LUY91_RS10785 | - | 2123947..2124336 (-) | 390 | WP_020444595.1 | hydroxymethylglutaryl-CoA synthase | - |
| LUY91_RS10790 | - | 2124372..2125046 (+) | 675 | WP_001106057.1 | IS6-like element IS257 family transposase | - |
| LUY91_RS10795 | - | 2125135..2126089 (-) | 955 | Protein_2097 | replication initiation factor domain-containing protein | - |
| LUY91_RS10800 | mobV | 2126616..2127858 (-) | 1243 | Protein_2098 | MobV family relaxase | - |
| LUY91_RS10805 | tet(K) | 2128044..2129423 (-) | 1380 | WP_000492283.1 | tetracycline efflux MFS transporter Tet(K) | - |
| LUY91_RS10810 | - | 2129620..2130294 (+) | 675 | WP_001106055.1 | IS6-like element IS257 family transposase | - |
| LUY91_RS10815 | - | 2130426..2130668 (+) | 243 | WP_001803415.1 | LytTR family DNA-binding domain-containing protein | - |
| LUY91_RS10820 | - | 2130739..2131029 (+) | 291 | WP_169301211.1 | DUF3021 domain-containing protein | - |
| LUY91_RS10825 | - | 2131462..2132136 (+) | 675 | WP_001105999.1 | IS6-like element IS257 family transposase | - |
| LUY91_RS10830 | - | 2132172..2132702 (+) | 531 | WP_041205518.1 | hypothetical protein | - |
| LUY91_RS10835 | merB | 2132897..2133547 (-) | 651 | WP_000790333.1 | organomercurial lyase MerB | - |
| LUY91_RS10840 | merA | 2133629..2135272 (-) | 1644 | WP_000193219.1 | mercury(II) reductase | - |
| LUY91_RS10845 | - | 2135330..2135668 (-) | 339 | WP_000968575.1 | hypothetical protein | - |
| LUY91_RS10850 | - | 2135803..2136483 (-) | 681 | WP_033842288.1 | cytochrome c biogenesis CcdA family protein | - |
| LUY91_RS10855 | - | 2136480..2136833 (-) | 354 | WP_033842287.1 | TlpA disulfide reductase family protein | - |
| LUY91_RS10860 | merR | 2136850..2137257 (-) | 408 | WP_000425271.1 | Hg(II)-responsive transcriptional regulator MerR | - |
| LUY91_RS10865 | - | 2137557..2138902 (-) | 1346 | Protein_2111 | dihydrolipoyl dehydrogenase family protein | - |
| LUY91_RS10870 | - | 2139185..2139859 (+) | 675 | WP_001105999.1 | IS6-like element IS257 family transposase | - |
| LUY91_RS10875 | - | 2139921..2142134 (+) | 2214 | Protein_2113 | type I restriction endonuclease subunit R | - |
| LUY91_RS10880 | - | 2142212..2142535 (-) | 324 | WP_001176049.1 | PepSY domain-containing protein | - |
| LUY91_RS10885 | - | 2142929..2143150 (-) | 222 | WP_002504703.1 | hypothetical protein | - |
| LUY91_RS10890 | - | 2143099..2143542 (-) | 444 | WP_000941333.1 | hypothetical protein | - |
| LUY91_RS10895 | - | 2143604..2144131 (-) | 528 | WP_000717929.1 | hypothetical protein | - |
| LUY91_RS10900 | - | 2144266..2144754 (-) | 489 | WP_000393586.1 | hypothetical protein | - |
| LUY91_RS10905 | - | 2144770..2145060 (-) | 291 | WP_000065261.1 | hypothetical protein | - |
| LUY91_RS10910 | - | 2145117..2145989 (-) | 873 | WP_000373149.1 | HTH domain-containing protein | - |
| LUY91_RS10915 | - | 2146159..2146305 (-) | 147 | Protein_2121 | JAB domain-containing protein | - |
| LUY91_RS10920 | - | 2146537..2147199 (-) | 663 | WP_001092058.1 | class I SAM-dependent methyltransferase | - |
| LUY91_RS10925 | - | 2147591..2147650 (+) | 60 | WP_181875734.1 | erythromycin resistance leader peptide | - |
| LUY91_RS10930 | erm(A) | 2147708..2148439 (+) | 732 | WP_001072197.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(A) | - |
| LUY91_RS10935 | - | 2148565..2149347 (-) | 783 | WP_000067268.1 | aminoglycoside nucleotidyltransferase ANT(9)-Ia | - |
| LUY91_RS10940 | - | 2149498..2149875 (-) | 378 | WP_000361059.1 | DUF6262 family protein | - |
| LUY91_RS10945 | - | 2149882..2151774 (-) | 1893 | WP_001557544.1 | site-specific integrase | - |
| LUY91_RS10950 | - | 2151771..2152856 (-) | 1086 | WP_000868132.1 | tyrosine-type recombinase/integrase | - |
| LUY91_RS10955 | - | 2152975..2153292 (-) | 318 | WP_130825069.1 | JAB domain-containing protein | - |
| LUY91_RS10960 | - | 2153313..2153819 (-) | 507 | WP_000849085.1 | DUF1643 domain-containing protein | - |
| LUY91_RS10965 | - | 2153835..2154146 (-) | 312 | WP_001083108.1 | DUF960 family protein | - |
| LUY91_RS10970 | - | 2154242..2154580 (-) | 339 | WP_000171557.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| LUY91_RS10975 | ccrC | 2154686..2156362 (-) | 1677 | WP_000676597.1 | cassette chromosome recombinase CcrC | - |
Sequence
Protein
Download Length: 448 a.a. Molecular weight: 52138.19 Da Isoelectric Point: 10.1760
>NTDB_id=637533 LUY91_RS10670 WP_000816499.1 2100759..2102105(+) (ccrA) [Staphylococcus aureus strain E1202_II_ST496]
MKRAIGYLRQSTTKQQSLPAQKQAIELLAPKHNIQNIQYISDKQSGRTDNRTGYQQVTERIQQRQCDVLCCYRLNRLHRN
LKNALKLMKLCQKYHVHILSVHDGYFDMDKAFDRLKLNIFMSLAELESDNIGEQVKNGLREKAKQGKLITTHAPFGYHYQ
NGTFIINNDESPTVKAVFNYYLQGYGYKKIAQYLEDDNKLITRKPYQVRNIIMNPNYCGRVINQYGQYNNMVPPIVSATK
YEHAQAIRNKKQLHCIPSENQLKQKIKCPCCDSTLTNMTIRKKHTLRYYICPKNMNESRFVCSFKGINAQKLEVQVLATC
QNFFQNQQLYSKINNAIHQRLKKQRVIEAKSTLTQEQLIDKLAKGMIDAESFRKQTHLMNQKHKTISSISDNQLQTSLQK
VIQKSFTLNMLHPYIDEIRITKNKALVGIYFKNEPLNIVNQTSQSSIA
MKRAIGYLRQSTTKQQSLPAQKQAIELLAPKHNIQNIQYISDKQSGRTDNRTGYQQVTERIQQRQCDVLCCYRLNRLHRN
LKNALKLMKLCQKYHVHILSVHDGYFDMDKAFDRLKLNIFMSLAELESDNIGEQVKNGLREKAKQGKLITTHAPFGYHYQ
NGTFIINNDESPTVKAVFNYYLQGYGYKKIAQYLEDDNKLITRKPYQVRNIIMNPNYCGRVINQYGQYNNMVPPIVSATK
YEHAQAIRNKKQLHCIPSENQLKQKIKCPCCDSTLTNMTIRKKHTLRYYICPKNMNESRFVCSFKGINAQKLEVQVLATC
QNFFQNQQLYSKINNAIHQRLKKQRVIEAKSTLTQEQLIDKLAKGMIDAESFRKQTHLMNQKHKTISSISDNQLQTSLQK
VIQKSFTLNMLHPYIDEIRITKNKALVGIYFKNEPLNIVNQTSQSSIA
Nucleotide
Download Length: 1347 bp
>NTDB_id=637533 LUY91_RS10670 WP_000816499.1 2100759..2102105(+) (ccrA) [Staphylococcus aureus strain E1202_II_ST496]
ATGAAACGAGCCATTGGTTATTTGCGCCAAAGTACAACGAAACAACAATCACTCCCAGCTCAAAAGCAAGCAATAGAATT
ATTAGCTCCAAAGCACAATATTCAAAATATCCAATACATTAGTGATAAGCAATCAGGCAGAACAGATAATCGAACAGGCT
ATCAACAAGTCACCGAACGCATCCAACAAAGACAATGTGACGTATTATGTTGTTATCGCTTGAATCGACTTCATCGCAAC
TTGAAAAATGCATTAAAACTCATGAAACTCTGTCAAAAATATCATGTTCATATTCTAAGTGTTCATGATGGCTATTTTGA
TATGGATAAAGCGTTTGATCGCCTAAAACTCAATATATTCATGAGTCTGGCTGAACTTGAATCCGATAATATTGGAGAAC
AAGTCAAAAATGGACTTAGAGAAAAGGCAAAACAAGGTAAACTCATAACGACCCATGCGCCTTTCGGTTATCACTATCAA
AATGGTACTTTCATCATTAATAATGATGAATCACCTACCGTCAAAGCTGTATTCAATTATTATCTTCAAGGATATGGCTA
CAAGAAGATTGCACAATATTTAGAAGACGATAATAAACTTATTACCCGCAAGCCTTATCAGGTACGAAATATAATTATGA
ACCCAAATTATTGTGGTCGTGTCATCAATCAATATGGTCAATATAACAATATGGTACCACCTATTGTTTCGGCAACGAAA
TATGAACATGCTCAAGCAATCCGTAATAAGAAGCAACTTCACTGTATACCTTCAGAGAATCAGCTGAAACAAAAGATCAA
ATGTCCTTGTTGTGACTCAACACTGACAAATATGACAATAAGAAAAAAACATACATTGCGATATTATATTTGTCCTAAAA
ATATGAATGAATCTCGCTTTGTCTGTTCATTCAAAGGAATAAATGCACAAAAATTAGAAGTTCAAGTCTTAGCTACATGT
CAGAACTTCTTTCAAAACCAACAGCTCTATTCAAAAATTAATAATGCAATTCATCAACGCCTCAAAAAACAAAGAGTGAT
AGAAGCTAAAAGTACGCTAACTCAAGAACAACTGATAGATAAACTTGCCAAAGGTATGATTGATGCTGAATCATTCAGAA
AACAGACTCATTTGATGAATCAAAAGCACAAAACCATATCCTCCATAAGTGATAATCAGTTACAAACATCACTACAAAAG
GTTATACAGAAAAGTTTCACGTTAAACATGCTGCATCCCTATATTGATGAAATTCGCATTACAAAAAATAAAGCCCTTGT
TGGGATCTATTTCAAAAATGAACCATTGAACATTGTGAACCAAACCTCGCAATCATCGATTGCTTAA
ATGAAACGAGCCATTGGTTATTTGCGCCAAAGTACAACGAAACAACAATCACTCCCAGCTCAAAAGCAAGCAATAGAATT
ATTAGCTCCAAAGCACAATATTCAAAATATCCAATACATTAGTGATAAGCAATCAGGCAGAACAGATAATCGAACAGGCT
ATCAACAAGTCACCGAACGCATCCAACAAAGACAATGTGACGTATTATGTTGTTATCGCTTGAATCGACTTCATCGCAAC
TTGAAAAATGCATTAAAACTCATGAAACTCTGTCAAAAATATCATGTTCATATTCTAAGTGTTCATGATGGCTATTTTGA
TATGGATAAAGCGTTTGATCGCCTAAAACTCAATATATTCATGAGTCTGGCTGAACTTGAATCCGATAATATTGGAGAAC
AAGTCAAAAATGGACTTAGAGAAAAGGCAAAACAAGGTAAACTCATAACGACCCATGCGCCTTTCGGTTATCACTATCAA
AATGGTACTTTCATCATTAATAATGATGAATCACCTACCGTCAAAGCTGTATTCAATTATTATCTTCAAGGATATGGCTA
CAAGAAGATTGCACAATATTTAGAAGACGATAATAAACTTATTACCCGCAAGCCTTATCAGGTACGAAATATAATTATGA
ACCCAAATTATTGTGGTCGTGTCATCAATCAATATGGTCAATATAACAATATGGTACCACCTATTGTTTCGGCAACGAAA
TATGAACATGCTCAAGCAATCCGTAATAAGAAGCAACTTCACTGTATACCTTCAGAGAATCAGCTGAAACAAAAGATCAA
ATGTCCTTGTTGTGACTCAACACTGACAAATATGACAATAAGAAAAAAACATACATTGCGATATTATATTTGTCCTAAAA
ATATGAATGAATCTCGCTTTGTCTGTTCATTCAAAGGAATAAATGCACAAAAATTAGAAGTTCAAGTCTTAGCTACATGT
CAGAACTTCTTTCAAAACCAACAGCTCTATTCAAAAATTAATAATGCAATTCATCAACGCCTCAAAAAACAAAGAGTGAT
AGAAGCTAAAAGTACGCTAACTCAAGAACAACTGATAGATAAACTTGCCAAAGGTATGATTGATGCTGAATCATTCAGAA
AACAGACTCATTTGATGAATCAAAAGCACAAAACCATATCCTCCATAAGTGATAATCAGTTACAAACATCACTACAAAAG
GTTATACAGAAAAGTTTCACGTTAAACATGCTGCATCCCTATATTGATGAAATTCGCATTACAAAAAATAAAGCCCTTGT
TGGGATCTATTTCAAAAATGAACCATTGAACATTGTGAACCAAACCTCGCAATCATCGATTGCTTAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrA | Staphylococcus aureus COL |
78.174 |
100 |
0.783 |
| ccrA | Staphylococcus aureus N315 |
72.383 |
100 |
0.725 |