Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   LUZ06_RS14360 Genome accession   NZ_CP089493
Coordinates   2881933..2882649 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain 0308_IA_ST247     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2876933..2887649
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LUZ06_RS14340 - 2878027..2878977 (+) 951 WP_000790330.1 LacI family DNA-binding transcriptional regulator -
  LUZ06_RS14345 - 2879126..2880610 (+) 1485 WP_000141414.1 sucrose-6-phosphate hydrolase -
  LUZ06_RS14350 - 2880607..2881566 (+) 960 WP_001253312.1 carbohydrate kinase -
  LUZ06_RS14355 - 2881754..2881861 (-) 108 WP_001790167.1 hypothetical protein -
  LUZ06_RS14360 agrA 2881933..2882649 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  LUZ06_RS14365 agrC 2882668..2883960 (-) 1293 WP_001554031.1 quorum-sensing sensor histidine kinase AgrC -
  LUZ06_RS14370 agrD 2883985..2884125 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  LUZ06_RS14375 - 2884285..2885889 (-) 1605 WP_000284571.1 IS1182-like element IS1182 family transposase -
  LUZ06_RS14380 agrB 2886048..2886536 (-) 489 Protein_2789 accessory gene regulator AgrB -
  LUZ06_RS14385 hld 2886826..2886906 (+) 81 WP_000046022.1 delta-hemolysin -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=637499 LUZ06_RS14360 WP_000688492.1 2881933..2882649(-) (agrA) [Staphylococcus aureus strain 0308_IA_ST247]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=637499 LUZ06_RS14360 WP_000688492.1 2881933..2882649(-) (agrA) [Staphylococcus aureus strain 0308_IA_ST247]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1