Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   LUZ02_RS10935 Genome accession   NZ_CP089491
Coordinates   2273570..2274286 (-) Length   238 a.a.
NCBI ID   WP_216763266.1    Uniprot ID   -
Organism   Staphylococcus aureus strain 0242_IV_ST30     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2268570..2279286
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LUZ02_RS10915 - 2269663..2270613 (+) 951 WP_000790322.1 LacI family DNA-binding transcriptional regulator -
  LUZ02_RS10920 - 2270762..2272246 (+) 1485 WP_000141410.1 sucrose-6-phosphate hydrolase -
  LUZ02_RS10925 - 2272243..2273202 (+) 960 WP_001253301.1 carbohydrate kinase -
  LUZ02_RS10930 - 2273391..2273498 (-) 108 WP_031789494.1 hypothetical protein -
  LUZ02_RS10935 agrA 2273570..2274286 (-) 717 WP_216763266.1 quorum-sensing response regulator AgrA Regulator
  LUZ02_RS10940 agrC 2274305..2275597 (-) 1293 WP_001670396.1 quorum-sensing sensor histidine kinase AgrC -
  LUZ02_RS10945 agrD 2275622..2275762 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  LUZ02_RS10950 agrB 2275759..2276328 (-) 570 WP_001105713.1 accessory gene regulator AgrB -
  LUZ02_RS10955 hld 2276618..2276698 (+) 81 WP_000046022.1 delta-hemolysin -
  LUZ02_RS10960 - 2277297..2278082 (-) 786 WP_000867943.1 carbon-nitrogen family hydrolase -
  LUZ02_RS10965 - 2278352..2278978 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27953.99 Da        Isoelectric Point: 6.3001

>NTDB_id=637437 LUZ02_RS10935 WP_216763266.1 2273570..2274286(-) (agrA) [Staphylococcus aureus strain 0242_IV_ST30]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLYDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=637437 LUZ02_RS10935 WP_216763266.1 2273570..2274286(-) (agrA) [Staphylococcus aureus strain 0242_IV_ST30]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATCCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCATAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACACGTATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTATATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATCGAATCTATAG
ATTCGAAAGAGCGCATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996